Patents by Inventor Ronald J. Biediger

Ronald J. Biediger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic and tetracyclic taxane intermediates
    Patent number: 6861537
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: March 1, 2005
    Assignee: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase Smith, Feng Liang, Krishna Murthi
  • Propanoic acid derivatives that inhibit the binding of integrins to their receptors
    Patent number: 6723711
    Abstract: A compound of the structure A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1(vascular cell adhesion molecule-1) and fibronectin; pharmaceutically active compositions comprising these compounds; and the use of these compounds for the control or prevention of diseases states in which &agr;4&bgr;1 is involved are also disclosed.
    Type: Grant
    Filed: October 9, 2001
    Date of Patent: April 20, 2004
    Assignee: Texas Biotechnology Corporation
    Inventors: Ronald J. Biediger, Brian Dupre, Linda K. Hamaker, George W. Holland, Jamal M. Kassir, Wen Li, Robert V. Market, Noel Nguyen, Ian L. Scott, Chengde Wu, E. Radford Decker
  • Carboxylic acid derivatives that inhibit the binding of integrins to their receptors
    Publication number: 20040063955
    Abstract: A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and to the use of such compounds either a above, or in formulations for the control or prevention of diseases states in which &agr;4&bgr;1 is involved.
    Type: Application
    Filed: October 9, 2001
    Publication date: April 1, 2004
    Inventors: Ronald J. Biediger, Qi Chen, E. Radford Decker, George W. Holland, Jamal M. Kassir, Wen Li, Robert V. Market, Ian L. Scott, Chengde Wu, Jian Li
  • Propanoic acid derivatives that inhibit the binding of integrins to their receptors
    Publication number: 20030199692
    Abstract: A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which &agr;4&bgr;1 is involved.
    Type: Application
    Filed: October 9, 2001
    Publication date: October 23, 2003
    Inventors: Ronald J. Biediger, Brian Dupre, Linda K. Hamaker, George W. Holland, Jamal M. Kassir, Wen Li, Robert V. Market, Noel Nguyen, Ian L. Scott, Chengde Wu, E. Radford Decker
  • Tricyclic and tetracyclic taxane intermediates
    Publication number: 20030050485
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Application
    Filed: July 12, 2002
    Publication date: March 13, 2003
    Applicant: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase C. Smith, Feng Liang, Krishna K. Murthi
  • Tricyclic and tetracyclic taxane intermediates
    Patent number: 6433189
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Grant
    Filed: July 17, 2001
    Date of Patent: August 13, 2002
    Assignee: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase Smith, Feng Liang, Krishna Murthi
  • Tricyclic and tetracyclic taxane intermediates
    Publication number: 20010053857
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Application
    Filed: July 17, 2001
    Publication date: December 20, 2001
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase C. Smith, Feng Liang, Krishna K. Murthi
  • Intermediates for tricyclic or tetracyclic taxanes
    Patent number: 6278026
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Grant
    Filed: June 15, 1999
    Date of Patent: August 21, 2001
    Assignee: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase Smith, Feng Liang, Krishna Murthi
  • Compounds that inhibit the binding of integrins to their receptors
    Patent number: 6262084
    Abstract: A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions thereof; and the use of the compounds either as above, or in formulations for the control or prevention of diseases states in which &agr;4&bgr;1 is involved.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: July 17, 2001
    Assignee: Texas Biotechnology Corporation
    Inventors: Ronald J. Biediger, Vanessa O. Grabbe, George W. Holland, Jamal Kassir, Karin M. Keller, Timothy P. Kogan, Shuqun Lin, Robert V. Market, Bore G. Raju, Ian L. Scott, Chengde Wu
  • N, N-disubstituted amides that inhibit the binding of integrins to their receptors
    Patent number: 6194448
    Abstract: A method for the inhibition of the binding of &agr;4&bgr;1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which &agr;4&bgr;1 is involved.
    Type: Grant
    Filed: October 14, 1999
    Date of Patent: February 27, 2001
    Assignee: Texas Biotechnology Corporation
    Inventors: Ronald J. Biediger, Vanessa O. Grabbe, George W. Holland, Jamal M. Kassir, Timothy P. Kogan, Shuqun Lin, Robert V. Market, Bore G. Raju, Ian L. Scott, Chengde Wu
  • Compounds that inhibit the binding of integrins to their receptors
    Patent number: 6096773
    Abstract: A method for the inhibition of the binding of .alpha..sub.4 .beta..sub.1 integrin to its receptors, for example VCAM-1 (vascular cell adhesion molecule-1) and fibronectin; compounds that inhibit this binding; pharmaceutically active compositions comprising such compounds; and the use of such compounds either as above, or in formulations for the control or prevention of diseases states in which .alpha..sub.4 .beta..sub.1 is involved.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: August 1, 2000
    Assignee: Texas Biotechnology Corporation, Inc.
    Inventors: Ian L. Scott, Bore G. Raju, Ronald J. Biediger, Vanessa O. Grabbe, Jamal Kassir, Karin M. Keller, Timothy P. Kogan, deceased, Shuqun Lin, Robert V. Market
  • Tricyclic and tetracyclic taxanes
    Patent number: 6005120
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Grant
    Filed: January 2, 1997
    Date of Patent: December 21, 1999
    Assignee: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase Smith, Feng Liang, Krishna Murthi
  • Synthetic process for the preparation of tricyclic and tetracyclic taxanes
    Patent number: 5760252
    Abstract: Process for the synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Grant
    Filed: December 19, 1996
    Date of Patent: June 2, 1998
    Assignee: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong Baik Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase Smith, Feng Liang, Krishna Murthi
  • Tricyclic and tetracyclic taxanes
    Patent number: 5637732
    Abstract: The synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Grant
    Filed: February 6, 1995
    Date of Patent: June 10, 1997
    Assignee: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong B. Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase Smith, Feng Liang, Krishna Murthi
  • Synthetic process for the preparation of tricyclic and tetracyclic taxanes
    Patent number: 5618952
    Abstract: Process for the synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Grant
    Filed: February 6, 1995
    Date of Patent: April 8, 1997
    Assignee: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong B. Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase Smith, Feng Liang, Krishna Murthi
  • Synthetic process for the preparation of taxol and other tricyclic and tetracyclic taxanes
    Patent number: 5405972
    Abstract: Process for the synthesis of taxol and other tricyclic and tetracyclic taxanes.
    Type: Grant
    Filed: January 27, 1994
    Date of Patent: April 11, 1995
    Assignee: Florida State University
    Inventors: Robert A. Holton, Carmen Somoza, Hyeong B. Kim, Mitsuru Shindo, Ronald J. Biediger, P. Douglas Boatman, Chase Smith, Feng Liang, Krishna Murthi