Patents by Inventor Ronald Jay Berenson

Ronald Jay Berenson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Thermally-activated self-immolative materials
    Patent number: 9580553
    Abstract: A polymer including a self-immolative polymer segment and a thermally-activated trigger moiety is described. The self-immolative polymer segment includes a head end, a tail end, and a plurality of repeating units. The trigger moiety includes a cycloaddition adduct that is covalently coupled to the head end of the self-immolative polymer segment. When the polymer is exposed to an activation temperature, the cycloaddition adduct undergoes retro-cycloaddition to release the self-immolative polymer segment. The self-immolative polymer segment then decomposes to sequentially release repeating units in a head-to-tail direction.
    Type: Grant
    Filed: December 9, 2013
    Date of Patent: February 28, 2017
    Assignees: University of Washington through its Center for Commercialization, Pacific Lutheran University
    Inventors: Andrew J. Boydston, Neal A. Yakelis, Ronald Jay Berenson, Derek C. Church, Gregory I. Peterson, Michael Larsen
  • THERMALLY-ACTIVATED SELF-IMMOLATIVE MATERIALS
    Publication number: 20150368403
    Abstract: A polymer including a self-immolative polymer segment and a thermally-activated trigger moiety is described. The self-immolative polymer segment includes a head end, a tail end, and a plurality of repeating units. The trigger moiety includes a cycloaddition adduct that is covalently coupled to the head end of the self-immolative polymer segment. When the polymer is exposed to an activation temperature, the cycloaddition adduct undergoes retro-cycloaddition to release the self-immolative polymer segment. The self-immolative polymer segment then decomposes to sequentially release repeating units in a head-to-tail direction.
    Type: Application
    Filed: December 9, 2013
    Publication date: December 24, 2015
    Applicants: University of Washington through its Center for Commercialization, Pacific Lutheran University
    Inventors: Andrew J. Boydston, Neal A. Yakelis, Ronald Jay Berenson, Derek C. Church, Gregory I. Peterson, Michael Larsen
  • Compositions and methods for modulating the activity of complement regulatory proteins on target cells
    Patent number: 8753639
    Abstract: This invention relates to agents capable of reducing the activity, amount or density of complement regulatory proteins (CRPs) on target cells. The invention also provides methods of identification of such agents, methods of making, and uses thereof.
    Type: Grant
    Filed: March 31, 2010
    Date of Patent: June 17, 2014
    Assignees: University of Washington through its Center for Commercialization, Compliment Corporation
    Inventors: André Lieber, Hongjie Wang, Ronald Jay Berenson, Darrick Carter
  • COMPOSITIONS AND METHODS FOR MODULATING THE ACTIVITY OF COMPLEMENT REGULATORY PROTEINS ON TARGET CELLS
    Publication number: 20100255011
    Abstract: This invention relates to agents capable of reducing the activity, amount or density of complement regulatory proteins (CRPs) on target cells. The invention also provides methods of identification of such agents, methods of making, and uses thereof.
    Type: Application
    Filed: March 31, 2010
    Publication date: October 7, 2010
    Applicants: UNIVERSITY OF WASHINGTON, COMPLIMENT CORPORATION
    Inventors: André Lieber, Hongjie Wang, Ronald Jay Berenson, Darrick Carter
  • Maturation of antigen-presenting cells using activated T cells
    Publication number: 20030082806
    Abstract: The present invention relates to methods for maturing antigen-presenting cells, and more particularly, to methods for maturing dendritic cells. Methods for generating mature and/or maturing antigen-presenting cells in vitro and in vivo are disclosed. The present invention also relates to compositions of cells, including mature antigen-presenting cells and/or activated T cells and their use in generating immune responses in vivo, and inhibiting the development of or preventing infectious diseases and cancers.
    Type: Application
    Filed: April 29, 2002
    Publication date: May 1, 2003
    Applicant: XCYTE Therapies, Inc.
    Inventors: Ronald Jay Berenson, Mark Bonyhadi, Stewart Craig, Dale Kalamasz, Tatsue Monji