Abstract: An expandable mechanical device for use during a thrombectomy medical procedure having enhanced visibility during imaging. Furthermore, the configuration of the eyelet and/or strut optimizes retention of the marker in the eyelet during the medical procedure without increasing overall profile of strut.

Abstract: A balloon guide catheter including a catheter shaft having a main lumen defined therein extending axially therethrough to receive a guidewire therein and an inflation lumen defined axially therein arranged semi-encircling the main lumen. The inflation lumen having an inlet port radially outward from the catheter shaft and an exhaust vent(s) disposed proximate the distal end of the catheter shaft. The exhaust vent(s) being disposed longitudinally through a distal terminating end of the inflation lumen or radially inward in fluid communication with the main lumen. A porous membrane is disposed at the exhaust vent(s) to permit only gas to pass therethrough. Secured about the outer surface proximate the distal end of the catheter shaft and coinciding with the inlet port is a balloon.

Abstract: A balloon guide catheter system including a balloon guide catheter having a catheter shaft that includes: (i) a main lumen; (ii) an inflation lumen; and (iii) an exhaust lumen. The terminating distal end of the inflation lumen and the terminating distal end of the exhaust lumen being in localized fluid communication with one another underneath the balloon while in a non-inflated state. A balloon is disposed about a distal region of an outer surface of the catheter shaft. The exhaust lumen is configured to purge the residual air in a proximal direction and out from a proximal region of the balloon guide catheter.

Abstract: A balloon catheter including a heating element disposed about a portion of an outer surface of a catheter shaft; a balloon mounted about the outer surface of the catheter shaft to coincide with the heating element; and thermally expandable material disposed inside the mounted balloon. The balloon catheter eliminating the need for pressurized liquid inflation media to be dispensed into/expelled from the balloon in order to inflate/deflate, respectively, the balloon.

Abstract: A balloon guide catheter having a sleeved inflation lumen secured with a wire wrap for improved inflation lumen kink protection and a welded balloon construction provides a robust and flexible catheter with an exceptionally large inner lumen relative to its outer profile and enables rapid and reliable balloon inflation and deflation in a highly deliverable and kink resistant catheter. Balloon guide catheters having multiple sleeved inflation lumens and proximal luers for utilizing the multiple inflation lumens are also provided.

Abstract: A gaming machine identifies a first pattern within a first play area including a plurality of first positions arranged in a plurality of first columns, determines whether the first pattern satisfies a predetermined first threshold based on a first position and a first symbol, identifies a second position associated with the first symbol in a second play area including a plurality of second positions arranged in a plurality of second columns, and associates the second position with a second symbol. Each first position is associated with a respective symbol of a plurality of symbols including the first symbol and the second symbol. The first pattern is associated with the first position. The first position is associated with the first symbol. Each second position is associated with a respective symbol of the plurality of symbols.

Abstract: Devices described herein include an actuated clot retrieval catheter system. The system includes a catheter having a frame disposed proximate the distal end of the catheter. The frame expands to form a seal with the inner wall of a vessel. In some examples, the frame also captures a clot for removal from the vessel. The frame is manufactured from a shape memory material that can be heat set into a predetermined shape. An electrical connection to an electronic circuit causes a current to run through the frame. The electrical resistance of the shape memory material causes the frame to heat and transition from a martensite to an austenite phase. When the frame is heat set into an expanded configuration, the current causes the frame heat and expand. When the frame is heat set into a closed configuration, the current causes the frame heat and collapse upon a clot.

Abstract: According to the present disclosure, there is provided a device which can have a funnel catheter having an expandable distal tip. The funnel catheter can originally be placed in a collapsed configuration for delivery through vasculature to a target thrombus location. Once positioned, the expandable tip can be radially expanded to create a funnel for aspirating or retrieving clots from a vessel. The funnel catheter can be at least partially enclosed by an outer sheath for purposes of delivery to the target site or to assist in expansion of the funnel catheter tip.

Abstract: A gaming machine identifies a first pattern within a first play area including a plurality of first positions arranged in a plurality of first columns, determines whether the first pattern satisfies a predetermined first threshold based on a first position and a first symbol, identifies a second position associated with the first symbol in a second play area including a plurality of second positions arranged in a plurality of second columns, and associates the second position with a second symbol. Each first position is associated with a respective symbol of a plurality of symbols including the first symbol and the second symbol. The first pattern is associated with the first position. The first position is associated with the first symbol. Each second position is associated with a respective symbol of the plurality of symbols.

Abstract: A gaming machine identifies a first pattern within a first play area including a plurality of first positions arranged in a plurality of first columns, determines whether the first pattern satisfies a predetermined first threshold based on a first position and a first symbol, identifies a second position associated with the first symbol in a second play area including a plurality of second positions arranged in a plurality of second columns, and associates the second position with a second symbol. Each first position is associated with a respective symbol of a plurality of symbols including the first symbol and the second symbol. The first pattern is associated with the first position. The first position is associated with the first symbol. Each second position is associated with a respective symbol of the plurality of symbols.

Abstract: Methods and devices for reducing emboli formation during medical procedures. In accordance with the present invention a first medical device is passed through a stenosed area and activated to block fluid flow through the lumen, a second medical device including a filter is passed through the stenosed area and deployed. The first medical device is then deactivated to restore fluid flow through the lumen.

Abstract: A support 103 for an embolic protection device comprises round wires 116 which may form one or more support hoops for a filter body. The circumferential hoop formed by the wires 116 ensures that in the expanded position, the filter body 102 will be supported by the support frame 103 in circumferential apposition with the interior wall of the vasculature. The wires 116 may have a strain distributing linkage element in the form of a loop 120. The loop 120 acts as a diameter or circumference adjuster allowing an embolic protection device to adapt to different Bessel contours and sizes whilst maintaining apposition with the vessel wall. The strain relieving geometry of the loops enhances the compliance of the bend points without creating a weakened hinge point, thus ensuring that there is no discontinuity in the circumferential seal against the vessel wall.

Abstract: An embolic protection device comprises a collapsible filter body and a filter support for the filter body. The filter support comprises a support frame defined by at least two wire segments having terminations. The terminations of adjacent segments are fixed relative to one another and extend generally parallel in a bifilar manner for enhanced trackability and flexibility.

Abstract: A device and method for liberating plaque from a lumen after a medical procedure has been formed. The device includes a catheter having a first expandable member and a second expandable member.

Abstract: A support 103 for an embolic protection device comprises round wires 116 which may form one or more support hoops for a filter body. The circumferential hoop formed by the wires 116 ensures that in the expanded position, the filter body 102 will be supported by the support frame 103 in circumferential apposition with the interior wall of the vasculature. The wires 116 may have a strain distributing linkage element in the form of a loop 120. The loop 120 acts as a diameter or circumference adjuster allowing an embolic protection device to adapt to different Bessel contours and sizes whilst maintaining apposition with the vessel wall. The strain relieving geometry of the loops enhances the compliance of the bend points without creating a weakened hinge point, thus ensuring that there is no discontinuity in the circumferential seal against the vessel wall.

Abstract: The method comprises the steps of advancing a guidewire from a first intermediate location to a further intermediate location which is proximal of the treatment location and, subsequently, advancing a medical device over the guidewire toward the further intermediate location. The method may comprise repeating these steps for additional intermediate locations. In one case the treatment location is in the carotid artery. The treatment location may be at or adjacent to the carotid bifurcation. An intermediate location may be at or adjacent to the aortic arch. An intermediate location may be at or adjacent to the carotid take-off. The medical device may be delivered over the guidewire using a delivery catheter. The delivery catheter and the medical device may be advanced through the vasculature without the use of a guide catheter.

Abstract: A collapsible filter element (40) for a transcatheter embolic protection device (1). The filter element (40) comprises a collapsible filter body (41) which is movable between a collapsed stored position for movement through a vascular system and an expanded position for extension across a blood vessel such that blood passing through the blood vessel is delivered through the filter element (40). A proximal inlet portion of the filter body (41) has two inlet openings (50) sized to allow blood and embolic material enter the filter body (41), and a distal outlet portion of the filter body (41) has a plurality of small outlet openings (51) to allow through-passage of blood, but to retain embolic material within the filter body (41). The filter body (41) is of an oriented polymeric material.

Abstract: A collapsible filter element (40) for a transcatheter embolic protection device (1). The filter element (40) comprises a collapsible filter body (41) which is movable between a collapsed stored position for movement through a vascular system and an expanded position for extension across a blood vessel such that blood passing through the blood vessel is delivered through the filter element (40). A proximal inlet portion of the filter body (41) has two inlet openings (50) sized to allow blood and embolic material enter the filter body (41), and a distal outlet portion of the filter body (41) has a plurality of small outlet openings (51) to allow through-passage of blood, but to retain embolic material within the filter body (41). The filter body (41) is of an oriented polymeric material.

Abstract: An embolic protection device comprises a collapsible filter element for delivery through a vascular system of a patient The filter element comprises a collapsible filter body 2 and a filter support 3 for the filter body. The filter body has an inlet end 4 and an outlet end 5, the inlet end 4 of the filter body has one or more inlet openings 6 sized to allow blood and embolic material enter the filter body 2 and the outlet end 5 of the filter body has a plurality of outlet openings 107 sized to allow through passage of blood but to retain undesired embolic material within the filter body 2. The filter support 3 is movable between a collapsed position for movement through the vascular system, and an extended outwardly projecting position to support the filter body in an expanded position The filter support 3 comprises a generally tubular support frame defined by at least one wire 16.

Abstract: Methods and devices for reducing emboli formation during medical procedures. In accordance with the present invention a first medical device is passed through a stenosed area and activated to block fluid flow through the lumen, a second medical device including a filter is passed through the stenosed area and deployed. The first medical device is then deactivated to restore fluid flow through the lumen.