Patents by Inventor Ronald Kuehne

Ronald Kuehne has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Acyltryptophanols
    Publication number: 20070060573
    Abstract: The present patent application relates to acyltryptophanols of the general formula I, in which Q, X, Y, W, R1, R2, R3, R4, R5, R8 have the meanings stated in the description. The compounds according to the invention are effective FSH antagonists and can be used for example for fertility control in men or in women, or for the prevention and/or treatment of osteoporosis.
    Type: Application
    Filed: August 9, 2006
    Publication date: March 15, 2007
    Inventors: Lars Wortmann, Arwed Cleve, Bernd Menzenbach, Hans-Peter Muhn, Gernot Langer, Anna Schrey, Ronald Kuehne, Marcu Koppitz, Dirk Kosemund
  • Novel tetrahydrocarbazole derivatives having improved biological action and improved solubility as ligands of G-protein coupled receptors (GPCRs)
    Publication number: 20060014818
    Abstract: The present invention provides novel tetrahydrocarbazole derivatives which have improved properties and which can be employed as inhibitors of GPCRs. This results in the possibility of using the novel compounds to treat pathological conditions whose severity depends on the pathobiochemical effect of GPCRs. The compounds of the invention act in particular via an antagonistic inhibition of the LHRH receptor. The invention further provides medicaments which comprise one or more of the novel compounds as active ingredient. The medicaments are suitable in particular to be employed in an oral dosage form for a mammal, in particular a human.
    Type: Application
    Filed: June 30, 2005
    Publication date: January 19, 2006
    Inventors: Klaus Paulini, Matthias Gerlach, Eckhard Günther, Emmanuel Polymeropoulos, Silke Baasner, Peter Schmidt, Ronald Kühne, Arvid Soderhall