Abstract: A cartridge for holding hemostatic clips comprises an outer casing and an elongated body positioned within the casing. The body includes a plurality of sets of pairs of walls on each side of a longitudinal line along the body. Each pair of walls defines a clip-receiving compartment between the walls, and each compartment is transversely aligned with a compartment on the other side of the longitudinal line so that each end of a generally U-shaped hemostatic clip can be received in one of the transversely aligned compartments. The walls of each pair of walls are flexible away from each other so that a clip can be removed by inserting the jaws of applying forceps between the walls and over the clip to flex the walls apart.