Abstract: The present invention relates to immobilized procainamide analogs, as well as to a method of making immobilized procainamide analogs. These immobilized analogs are prepared by activating the carboxyl group on a substituted p-benzoic acid derivative toward nucleophilic attack; reacting the activated benzoic acid derivative with a polyamine to produce the benzoic acid derivative of Formula 3: and binding the benzoic acid derivative of Formula 3 to a latex polymer having functional groups that react with aliphatic amino groups. A method of conducting an immunoassay using the immobilized procainamide analog Formula 3 is described, comprising the steps of preparing a solution comprising said immobilized procainamide analog; adding a sample suspected of containing procainamide to said solution; adding an anti-procainamide antibody to said solution and observing the rate of increase in solution turbidity following antibody addition.

Abstract: Lidocaine analogs, latex particle-analog conjugates, and methods of making and using the same. The analogs have the formula: wherein Z comprises a nucleophilic group and optionally a protecting group; L is a linker; R1, R2, R3, R4, R5 are each independently H, a protecting group, or C1 to C6 alkyls, provided that R1 and R3 may form a six membered ring with the nitrogen and carbon atom to which R1 and R3 are attached; R6 and R7 are each independently H or C1 to C20 alkyls; and including salts thereof. The analogs are immobilized on latex particles and prepared for use in assays for lidocaine.

Abstract: A method and apparatus of manufacturing a web which is striped with add-on material, comprising: a first arrangement which establishes a sheet of base web from a first slurry and moves the established sheet along a first path; a second arrangement for preparing a second slurry; a moving orifice applicator operative so as to repetitively discharge the second slurry upon the moving sheet of base web, the moving orifice applicator comprising: a chamber box arranged to establish a reservoir of the second slurry across the first path; an endless belt having an orifice, the endless belt received through the chamber box; a drive arrangement operative upon the endless belt to continuously move the orifice along an endless path and repetitively through the chamber box, the orifice when communicated with the reservoir being operative to discharge the second slurry from the reservoir through the orifice; a flow distribution system for introducing the second slurry into the chamber box at spaced-apart feed locations alon

Abstract: An improved nail transfer device includes an inlet and an outlet with a transfer passage disposed therebetween. A cycling indexer transfers nails one at a time from the inlet to the outlet. A first magnet draws a nail from the inlet to the transfer passage and a second magnet adjacent to the outlet dislodges the nails from the transfer passage and loads the nail into the automatic nail gun.

Abstract: An improved apparatus and process for the operation of a down-flow granular medium bed filter is disclosed. A splash plate for dissipating the force of influent liquid is rotatably connected to support means, allowing the plate to rotate from a position parallel to the bed surface to a position perpendicular to the bed surface upon the liquid above the bed rising to a selected first level. The splash plate is maintained in the perpendicular position for the remainder of the filtration cycle, the backwash cycle and any chemical cleaning cycle, allowing unobstructed operation of the filter bed. The splash plate returns to the original position at the start of another filtration cycle.

Abstract: An improved method for maintaining a granular medium filter in a clean, operable condition is disclosed. The time interval required for the level of liquid above the filter bed to drain from a backwash outlet level to the upper bed surface level following a backwash cycle is monitored. Upon this measured draindown time exceeding a predetermined interval of time, a chemical cleaning cycle is initiated for the granular medium bed filter.

Abstract: A tobacco leaf mixture containing lighter and heavier fractions is fed into one side of a housing while an airstream flow is introduced at the other side of the housing and in an upwardly directed flow course so as to cause it to entrain the lighter fraction of the mixture therein, with the heavier fraction falling to the bottom of the housing. A suction lift is maintained at the top of the housing to increase the velocity of the lighter fraction containing air flow outwardly from the housing. The lighter fraction containing air flow is then delivered to a separator unit to recover the lighter fraction. The lighter fraction can, for example, be the laminae material from which shredded cigarette tobacco filler is made.