Abstract: A tool assembly for use with an electrosurgical device for cutting tissue includes a base portion, a return lead, an electrical insulator, a center pin, and an active lead. The center pin extends from the base portion and through a lumen of the electrical insulator. The active lead is securely fixed to the base portion and extends between the base portion and a distal portion of the center pin such that a portion of the active lead extends around the distal portion of the center pin and first and second segments of the active lead are spaced apart from the return lead. Upon activation, electrosurgical energy is transmitted from the active lead through tissue to the return lead to cut tissue in contact with the active lead.

Abstract: An electrosurgical device for cutting tissue includes a body portion and a tool portion extending distally from the body portion. The tool portion defines a longitudinal axis. The tool portion includes a return lead adapted to be electrically coupled to a return terminal of an electrosurgical energy source, first and second electrical insulators disposed on a first surface of the return lead, and an active lead adapted to be electrically coupled to an active terminal of the electrosurgical energy source. The first electrical insulator is disposed distal of the second electrical insulator. The active lead extends through the first and second electrical insulators such that the active lead and the first surface of the return lead define a gap therebetween. Upon activation of the electrosurgical energy source, electrosurgical energy is transmitted from the active lead through tissue to the return lead to cut the tissue.

Abstract: An electrophoretic device for detecting biomarkers in collected bodily fluid and methods of using the same.

Abstract: An electrophoretic device for detecting biomarkers in collected bodily fluid and methods of using the same.

Abstract: A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a first treatment device having a plurality of electrodes. The electrodes are maintained in axial alignment and fixed radial spacing in retracted and extended positions. The device includes a basket having a plurality of arms. The arms are maintained in a fixed radial spacing in the collapsed position of the basket.

Abstract: A tool assembly for use with an electrosurgical device for cutting tissue includes a base portion, a return lead, an electrical insulator, a center pin, and an active lead. The center pin extends from the base portion and through a lumen of the electrical insulator. The active lead is securely fixed to the base portion and extends between the base portion and a distal portion of the center pin such that a portion of the active lead extends around the distal portion of the center pin and first and second segments of the active lead are spaced apart from the return lead. Upon activation, electrosurgical energy is transmitted from the active lead through tissue to the return lead to cut tissue in contact with the active lead.

Abstract: A tool assembly for use with an electrosurgical device for cutting tissue includes a base portion, a return lead, an electrical insulator, a center pin, and an active lead. The center pin extends from the base portion and through a lumen of the electrical insulator. The active lead is securely fixed to the base portion and extends between the base portion and a distal portion of the center pin such that a portion of the active lead extends around the distal portion of the center pin and first and second segments of the active lead are spaced apart from the return lead. Upon activation, electrosurgical energy is transmitted from the active lead through tissue to the return lead to cut tissue in contact with the active lead.

Abstract: A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a first treatment device having a plurality of electrodes. The electrodes are maintained in axial alignment and fixed radial spacing in retracted and extended positions. The device includes a basket having a plurality of arms. The arms are maintained in a fixed radial spacing in the collapsed position of the basket.

Abstract: The present invention provides gastrointestinal devices for limiting transfer and contact of material across luminal walls along a segment of the gastrointestinal tract (e.g., at the duodenum and/or upper jejunum). Devices of the invention include a gastrointestinal sleeve, an anchor, and a flange for attachment to a luminal wall proximal to the pyloric orifice. The invention also provides methods of use associated with such gastrointestinal devices, including methods for delivery, removal, and treatment of metabolic disorders, such as type 2 diabetes, non-alcoholic steatohepatitis, non-alcoholic fatty liver disease, obesity, and related comorbidities thereof by implanting gastrointestinal devices.

Abstract: An electrosurgical device for cutting tissue includes a body portion and a tool portion extending distally from the body portion. The tool portion defines a longitudinal axis. The tool portion includes a return lead adapted to be electrically coupled to a return terminal of an electrosurgical energy source, first and second electrical insulators disposed on a first surface of the return lead, and an active lead adapted to be electrically coupled to an active terminal of the electrosurgical energy source. The first electrical insulator is disposed distal of the second electrical insulator. The active lead extends through the first and second electrical insulators such that the active lead and the first surface of the return lead define a gap therebetween. Upon activation of the electrosurgical energy source, electrosurgical energy is transmitted from the active lead through tissue to the return lead to cut the tissue.

Abstract: An electrosurgical device for cutting tissue includes a body portion and a tool portion extending distally from the body portion. The tool portion includes a return lead, first and second electrical insulators, and an active lead. The return lead is adapted to be electrically coupled to a return terminal of an electrosurgical energy source. The return lead defines a recess between proximal and distal portions of the return lead. The first and second electrical insulators are disposed on the respective proximal and distal portions of the return lead. The active lead extends through the first and second electrical insulators and across the recess of the return lead. Upon activation of the electrosurgical energy source, electrosurgical energy is transmitted from the active lead through tissue in contact with the active lead to the return lead to cut tissue in contact with the active lead.

Abstract: A tool assembly for use with an electrosurgical device for cutting tissue includes a base portion, a return lead, an electrical insulator, a center pin, and an active lead. The center pin extends from the base portion and through a lumen of the electrical insulator. The active lead is securely fixed to the base portion and extends between the base portion and a distal portion of the center pin such that a portion of the active lead extends around the distal portion of the center pin and first and second segments of the active lead are spaced apart from the return lead. Upon activation, electrosurgical energy is transmitted from the active lead through tissue to the return lead to cut tissue in contact with the active lead.

Abstract: The present invention provides gastrointestinal devices for limiting transfer and contact of material across luminal walls along a segment of the gastrointestinal tract (e.g., at the duodenum and/or upper jejunum). Devices of the invention include a gastrointestinal sleeve, an anchor, and a flange for attachment to a luminal wall proximal to the pyloric orifice. The invention also provides methods of use associated with such gastrointestinal devices, including methods for delivery, removal, and treatment of metabolic disorders, such as type 2 diabetes, non-alcoholic steatohepatitis, non-alcoholic fatty liver disease, obesity, and related comorbidities thereof by implanting gastrointestinal devices.

Abstract: A surgical instrument includes a housing and a motor. An elongated member extends from the housing. An end effector is at a distal end of the elongated member. The end effector includes a jaw member including a guard. The guard has a number of serrations extending from a proximal end of the jaw member to a distal end of the jaw member. The guard defines corresponding pockets between the serrations. The guard is coupled to the motor to induce reciprocation of the guard relative to the blade upon activation of the motor. A blade is recessed within the guard to expose a cutting edge of the blade between the pockets. The pockets engage tissue. A treatment tip is at a distal end of the guard. The treatment tip connects to an energy source. The treatment tip treats tissue upon activation of the treatment tip.

Abstract: An electrophoretic device for detecting biomarkers in collected bodily fluid and methods of using the same.

Abstract: An electrophoretic device for detecting biomarkers in collected bodily fluid and methods of using the same.

Abstract: A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a first treatment device having a plurality of electrodes. The electrodes are maintained in axial alignment and fixed radial spacing in retracted and extended positions. The device includes a basket having a plurality of arms. The arms are maintained in a fixed radial spacing in the collapsed position of the basket.

Abstract: An electrophoretic device for detecting biomarkers in collected bodily fluid and methods of using the same.

Abstract: A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a first treatment device having a plurality of electrodes. The electrodes are maintained in axial alignment and fixed radial spacing in retracted and extended positions. The device includes a basket having a plurality of arms. The arms are maintained in a fixed radial spacing in the collapsed position of the basket.

Abstract: A system for controlling operation of a radiofrequency treatment device to apply radiofrequency energy to tissue to treat tissue to create lesions without ablating the tissue. The system includes a device having flexible outer tube, an expandable basket having a plurality of arms movable from a collapsed position to an expanded position, a plurality of electrodes movable from a retracted position to an extended position to extend through the openings in the arms, and an advancer slidably disposed within the outer tube to move the electrodes. An elongated spacer is positioned within the outer tube, the spacer having a central lumen to receive the advancer and to maintain a central position of the advancer.