Patents by Inventor Ronald Lawrence Hayes

Ronald Lawrence Hayes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENDOTHELIAL-MONOCYTE ACTIVATING POLYPEPTIDE II (EMAP-II), A BIOMARKER FOR USE IN DIAGNOSIS AND TREATMENT OF BRAIN INJURY
    Publication number: 20150057193
    Abstract: A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP II) and comparing to a control. An increase of EMAP II indicates the presence of traumatic brain injury and a decrease of EMAP II indicates the presence of ischemic brain injury.
    Type: Application
    Filed: September 26, 2014
    Publication date: February 26, 2015
    Inventors: JITENDRA RAMANLAL DAVE, CHANGPING YAO, ANTHONY JOSEPH WILLIAMS, XI-CHUN MAY-LU, FRANK CASPER TORTELLA, KA-WANG KEVIN WAND, RONALD LAWRENCE HAYES
  • IN VITRO DIAGNOSTIC DEVICES FOR NERVOUS SYSTEM INJURY AND OTHER NEURAL DISORDERS
    Publication number: 20140303041
    Abstract: The present invention relates to an exemplary in vitro diagnostic (IVD) device used to detect the presence of and/or severity of neural injuries or neuronal disorders in a subject. The IVD device relies on an immunoassay which identifies biomarkers that are diagnostic of neural injury and/or neuronal disorders in a biological sample, such as whole blood, plasma, serum, cerebrospinal fluid (CSF). The inventive IVD device may measure one or more of several neural specific markers in a biological sample and output the results to a machine readable format wither to a display device or to a storage device internal or external to the IVD.
    Type: Application
    Filed: May 11, 2012
    Publication date: October 9, 2014
    Applicants: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION INC., BANYAN BIOMARKERS, INC.
    Inventors: Ronald Lawrence Hayes, Ka-Wang (Kevin) Wang, Andreas Jeromin, Ming-Cheng Liu, Monika Oli
  • Endothelial monocyte activation polypeptide II, a biomarker for use in diagnosis and treatment of brain injury
    Publication number: 20110028349
    Abstract: A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury.
    Type: Application
    Filed: August 19, 2010
    Publication date: February 3, 2011
    Inventors: Jitendra Ramanlal Dave, Changping Yao, Anthony Joseph Williams, Xi-Chun May, Frank Casper Tortella, Ka-Wang Kevin Wang, Ronald Lawrence Hayes
  • Endothelial-monocyte activating polypeptide II, a biomarker for use in diagnosis of brain injury
    Patent number: 7799536
    Abstract: A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury. Detection of EMAP-II can be done in brain tissue, biofluids such as cerebrospinal fluid or blood (including plasma and serum).
    Type: Grant
    Filed: October 28, 2008
    Date of Patent: September 21, 2010
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Jitendra Ramanlal Dave, Changping Yao, Anthony Joseph Williams, Xi-Chun May, Frank Casper Tortella, Ka-Wang Kevin Wang, Ronald Lawrence Hayes
  • Endothelial-monocyte activating polypeptide II, a biomarker for use in diagnosis and treatment of brain injury
    Publication number: 20090068691
    Abstract: A diagnostic tool and method of diagnosing brain injury and brain injury type (traumatic vs. ischemic) by detecting the level of expression of endothelial monocyte-activating polypeptide II (EMAP-II) and comparing to a control. An increase of EMAP-II indicates the presence of traumatic brain injury and a decrease of EMAP-II indicates the presence of ischemic brain injury.
    Type: Application
    Filed: October 28, 2008
    Publication date: March 12, 2009
    Inventors: Jitendra Ramanlal Dave, Changping Yao, Anthony Joseph Williams, Xi-Chun May, Frank Casper Tortella, Ka-Wang Kevin Wang, Ronald Lawrence Hayes