Abstract: The present disclosure is directed to a device for redressing a tapered portion of an orthopaedic implant. The device comprises a grinding member adapted to matingly contact or engage at least a portion of the tapered portion; a housing adapted for removably receiving the grinding member therein, the housing having an opening at or towards a distal end to receive the tapered portion therethrough; and a connector at or towards a proximal end for operably connecting the housing to a drill member.

Abstract: Techniques are disclosed for providing method for providing an event timer for event synchronization across Kubernetes clusters. The event timer is configured to provide event synchronization on behalf of microservice instances in the cloud computing environment. In response to a request for an event timer for a timed event, it is determined whether the requested event timer has been started for a second microservice instance. If the requested event timer has been started, a state of the requested event timer is sent to the first microservice instance If the requested event timer has not been started, the requested event timer is instantiated, and a state of the instantiated event timer is stored in a database. The instantiated event timer is independent of the first and second microservice instances. In response to an expiration of the event timer, a single callback for processing of the event is generated.

Abstract: A TAT-FXN fusion polypeptide useful in treating subjects diagnosed with Friedrich's Ataxia, hypertrophic cardiomyopathy, or both are disclosed, as are related methods of treatment and pharmaceutical compositions.

Abstract: A TAT-FXN fusion polypeptide useful in treating subjects diagnosed with Friedrich's Ataxia, hypertrophic cardiomyopathy, or both are disclosed, as are related methods of treatment and pharmaceutical compositions.

Abstract: A computing network comprising a computing service provider and an edge computing network is managed. A trusted device establishes a root of trust at the edge computing network via a trusted component on the trusted device. In response to receiving a first indication of a disconnection or degradation of communications between the computing service provider and the edge computing network, the edge computing network initiates an autonomous mode at the edge computing network. While the edge computing network is operating in the autonomous mode, the trusted device detects new devices that are attempting to access computing resources in the edge computing network. The trusted device stores data pertaining to new devices that were not authorized to access the computing resources in the edge computing network.

Abstract: Disclosed are manufactured articles, and methods therefor, for forming and attaching grips, handles and coverings for tools where a fastener for securing an outer cover is designed in coordination with a complementary shaped opening in the outer cover and the fastener and outer cover both comprise features to mechanically engage one another. In preferred embodiments, the outer cover and fastener are designed together in a common 3D modeling computer application and are then additively manufactured based on the complementary shaped models of the outer cover and the fastener.

Abstract: The present disclosure relates to systems, methods, and computer readable media for facilitating placement of network functions based on a network slice profile that is received and based on internal knowledge of a cloud computing system having network resources thereon. The systems described herein involve tagging the network resources with various characteristics, generating resource management profiles including instructions that may be used to supplement information from the slice profile(s), and matching an incoming slice profile with a resource management profile. The systems described herein facilitate rolling out a deployment of network functions on the network resources in accordance with information from the resource management profile in a way that optimizes resources and allows automated placement of network functions based on a received network slice.

Abstract: The present disclosure relates to systems, methods, and computer readable media for receiving and processing a request to deploy network functions across one or more deployment areas of a telecommunications network. Systems described herein process a request by applying a hierarchical configuration model including a hierarchy of configuration management instructions that can be applied to a request that complies with a format of the hierarchical configuration model. Features described herein facilitate deployment of unique configuration instructions across multiple network functions and across multiple deployment areas based on a single request and without further user interaction with respect to each of multiple network functions.

Abstract: The present disclosure relates to a network function configuration system that efficiently, accurately, and flexibly manages network function configurations in a cloud computing system for a 5G (and beyond) telecommunications network. For example, the network function configuration system utilizes configuration snapshots to perform batches of configuration updates atomically to network functions of a mobile packet core that is implemented in a cloud computing system. To illustrate, in a cloud computing system (such as a core network), network functions run in a current state. To modify the configuration snapshot to a desired state, numerous network function configuration changes must often be applied.

Abstract: Described are examples for providing end-to-end intent definition of network functions for network slice management. Intents are defined for each level of network constituent including slices, slice subnets, and management functions. A system of intent based network slice management includes a network slice management function (NSMF) configured to receive a service profile from a communication service management function (CSMF) and derive an intent for each desired network slice subnet for a network slice subnet management function (NSSMF). The NSSMF is configured to derive requirements for a plurality of network functions (NFs) and provide an intent defining the requirements of a respective NF to a network function management function (NFMF). The NFMF is configured to receive the intent for the respective NF via an intent-based interface for management of NFs and derive a network resource model (NRM) for the respective NF based on the intent.

Abstract: A computing network comprising a computing service provider and an edge computing network is managed. A trusted device establishes a root of trust at the edge computing network via a trusted component on the trusted device. In response to receiving a first indication of a disconnection or degradation of communications between the computing service provider and the edge computing network, the edge computing network initiates an autonomous mode at the edge computing network. While the edge computing network is operating in the autonomous mode, the trusted device detects new devices that are attempting to access computing resources in the edge computing network. The trusted device stores data pertaining to new devices that were not authorized to access the computing resources in the edge computing network.

Abstract: Described are examples for providing intent based network slice management using a management data analytics function (MDAF) to predict deficiencies. A network management system receives an intent for a network slice constituent. The network management system configures computing resources for the network slice constituent to satisfy the intent based on expected performance of the computing resources. The network management system receives feedback with respect to actual performance of the network slice constituent. The network management system determines, based on analysis of the feedback by a management data analytics function (MDAF), a predicted deficiency of the network slice constituent not being able to satisfy the intent. The network management system modifies the configuration of the computing resources based on the feedback and the predicted deficiency to satisfy the intent.

Abstract: The present disclosure relates to systems, methods, and computer readable media for managing and maintaining deployments of configurations on network functions in a telecommunications network. In particular, examples herein relate to implementations of a configuration management system and reconciliation agents that cooperatively perform multi-tiered reconciliation of configuration states for deployments of network functions. The systems described herein can perform multiple levels of reconciliation checks on a plurality of network functions to ensure that configurations of the network functions are effectively maintained and consistent with a desired state (e.g., a goal state) of the deployment(s) of network functions.

Abstract: The present disclosure relates to systems, methods, and computer readable media for receiving and processing a request to deploy network functions across one or more deployment areas of a telecommunications network. Systems described herein process a request by applying a hierarchical configuration model including a hierarchy of configuration management instructions that can be applied to a request that complies with a format of the hierarchical configuration model. Features described herein facilitate deployment of unique configuration instructions across multiple network functions and across multiple deployment areas based on a single request and without further user interaction with respect to each of multiple network functions.

Abstract: The present disclosure relates to systems, methods, and computer-readable media for configuring a network function in a core network of a telecommunications environment. For example, systems described herein involve collecting transmission data including timing and success/failure data for use in generating a retry policy that includes rules and instructions that govern transmission of retries between computing nodes. Once generated, the retry policy may be applied to message packages by selectively transmitting message retries based on specific timing delays that are determined from the collected transmission data. This generation and implementation of the retry policy may improve the latency and success rate of messages transmitted by computing nodes within a core network architecture, thereby improving network conditions in a variety of ways.

Abstract: Methods to assess a pediatric subject having a single ventricle heart include identifying a difference between concentration levels of metabolic biomarkers and reference concentration levels and then assessing the pediatric subject based on the identified differences.

Abstract: Computing resources are managed in a computing network comprising a computing service provider and an edge computing network. The edge computing network receives an indication of a disconnection of communications between the computing service provider and the edge computing network. In response to the indication, the edge computing network initiates an autonomous mode at the edge computing network. The edge computing network is configured to continue providing computing and network services at the edge computing network while the edge computing network is operating in the autonomous mode.

Abstract: Described are examples for providing end-to-end intent definition of network functions for network slice management. Intents are defined for each level of network constituent including slices, slice subnets, and management functions. A system of intent based network slice management includes a network slice management function (NSMF) configured to receive a service profile from a communication service management function (CSMF) and derive an intent for each desired network slice subnet for a network slice subnet management function (NSSMF). The NSSMF is configured to derive requirements for a plurality of network functions (NFs) and provide an intent defining the requirements of a respective NF to a network function management function (NFMF). The NFMF is configured to receive the intent for the respective NF via an intent-based interface for management of NFs and derive a network resource model (NRM) for the respective NF based on the intent.

Abstract: Described are examples for providing intent based network slice management using a management data analytics function (MDAF) to predict deficiencies. A network management system receives an intent for a network slice constituent. The network management system configures computing resources for the network slice constituent to satisfy the intent based on expected performance of the computing resources. The network management system receives feedback with respect to actual performance of the network slice constituent. The network management system determines, based on analysis of the feedback by a management data analytics function (MDAF), a predicted deficiency of the network slice constituent not being able to satisfy the intent. The network management system modifies the configuration of the computing resources based on the feedback and the predicted deficiency to satisfy the intent.

Abstract: Computing resources are managed in a computing network comprising a computing service provider and an edge computing network. The edge computing network receives an indication of a disconnection of communications between the computing service provider and the edge computing network. In response to the indication, the edge computing network initiates an autonomous mode at the edge computing network. The edge computing network is configured to continue providing computing and network services at the edge computing network while the edge computing network is operating in the autonomous mode.