Patents by Inventor Ronald Micetich

Ronald Micetich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Triazoles as therapeutic agents for fungal infections
    Patent number: 6153616
    Abstract: A compound of formula I, or an optical isomer or pharmaceutically acceptable salt thereof, ##STR1## is disclosed as well as a pharmaceutical composition and a method of treating or preventing a fungal infection using the compound.
    Type: Grant
    Filed: January 16, 1998
    Date of Patent: November 28, 2000
    Assignees: Synphar Laboratories, Inc., Taiho Pharmaceuticals Co., Ltd.
    Inventors: Mohsen Daneshtalab, Yadagiri Bathini, Dai Nguyen, Inderjit Sidhu, Mark Abel, Chan Ha, Sameeh Salama, Jehangir Khan, Ronald Micetich, Tetsuo Furukawa, Norio Unemi
  • 3-(substituted methyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one derivatives useful as antitumor agents
    Patent number: 5994342
    Abstract: The present invention is based on the discovery that certain 3-(substituted methyl)-4-oxa-1-azabicyclo[3.2.0]heptan-7-one derivatives of formula I or a pharmaceutically acceptable salt thereof are useful as antitumor agents against sensitive and resistant tumor cells. ##STR1## Wherein X is NH or O, and R is defined in the specification.
    Type: Grant
    Filed: April 4, 1997
    Date of Patent: November 30, 1999
    Assignees: Taiho Pharmaceutical Co., Ltd., Synphar Laboratories Inc.
    Inventors: Rajeshwar Singh, Tomohiro Yamashita, Charles Fiakpui, George Thomas, Chan Ha, Hiroshi Matsumoto, Toshio Otani, Shinji Oie, Ronald Micetich
  • 3-(7-oxo-1-aza-4-oxabicyclo[3.2.0]hept-3-yl)alanine derivative as antitumor agent
    Patent number: 5652234
    Abstract: The present invention relates to the use of 3-(7-oxo-1-aza-4-oxabicyclo[3.2.0]hept-3-yl)alanine derivatives of formula (I) or a pharmaceutically acceptable salt thereof, as antitumor agents. ##STR1## Wherein R is: hydrogen or COOR.sub.2 wherein R.sub.2 is C.sub.1 -C.sub.3 alkyl group which may be substituted with aryl group.Wherein R.sub.1 is:hydrogen or C.sub.1 -C.sub.3 alkyl group which may be substituted with one or two aryl groups.
    Type: Grant
    Filed: October 6, 1995
    Date of Patent: July 29, 1997
    Assignees: Taiho Pharmaceutical Co., Limited, SynPhar Laboratories, Inc.
    Inventors: Rajeshwar Singh, Tomohiro Yamashita, Charles Fiakpui, George Thomas, Chan Ha, Hiroshi Matsumoto, Toshio Otani, Shinji Oie, Ronald Micetich
  • 4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives as antitumor agents
    Patent number: 5561126
    Abstract: The present invention relates to the use of 4-oxa-1-azabicyclo [3,2,0] heptan-7-one derivatives of formula (I) or a pharmaceutically acceptable salt thereof, as antitumor agents. ##STR1## Wherein R is --OCOR.sub.1 group wherein R.sub.1 is hydrogen atom, a C.sub.1-9 alkyl group which may be substituted by either one or two substituents selected together from halogen atom, hydroxy, carboxy group or (3RS,5SR)-(4-oxo-1-azabicyclo[3,2,0]heptan-7-one-3-yl) methyloxycarbonyl, a C.sub.2-17 alkenyl group, which may be substituted by carboxy group or (3RS,5SR)-(4-oxa-1-azabicyclo [3,2,0]heptan-7-one-3-yl)methyloxycarbonyl, A C.sub.2-4 alkynyl group, a C.sub.3-6 cycloalkyl group which may be substituted by carboxy group or phenyl group which may have 1, 2 or 3 substituents selected from the group consisting of cyano group, halogen atom, C.sub.1-6 alkoxy group which may be substituted by carboxy group, C.sub.1-6 alkyl group, amino group or hydroxy group.--OR.sub.2 wherein R.sub.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: October 1, 1996
    Assignees: Taiho Pharmaceutical Co., Ltd., Synphar Laboratories, Inc.
    Inventors: Toshio Otani, Shinji Oie, Hiroshi Matsumoto, Mark Tempest, Ronald Micetich, Rajeshwar Singh, Tomohiro Yamashita