Patents by Inventor Ronald P. Quintana

Ronald P. Quintana has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6358897
    Abstract: Improved stability, liquid enzyme compositions containing an alkylated trypsin and methods involving the combined use of these compositions with an aqueous composition are disclosed for the cleaning or simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: September 1, 1998
    Date of Patent: March 19, 2002
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bor-Shyue Hong, Bahram Asgharian, Ronald P. Quintana
  • Patent number: 6139646
    Abstract: Improved stability, liquid enzyme compositions containing an alkylated trypsin and methods involving the combined use of these compositions with an aqueous composition are disclosed for the cleaning or simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: October 18, 1999
    Date of Patent: October 31, 2000
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bahram Asgharian, Bor-Shyue Hong, Ronald P. Quintana
  • Patent number: 5948738
    Abstract: Stable liquid enzyme compositions containing an ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: October 6, 1998
    Date of Patent: September 7, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth A. Rosenthal
  • Patent number: 5939369
    Abstract: Stable liquid enzyme compositions containing an ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: August 2, 1996
    Date of Patent: August 17, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth A. Rosenthal
  • Patent number: 5919313
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: May 30, 1997
    Date of Patent: July 6, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bahram Asgharian, Ronald P. Quintana, Bor-Shyue Hong
  • Patent number: 5868868
    Abstract: The invention discloses PEG-modified proteases, compositions containing these modified enzymes, and methods for using them to clean contact lenses. The methods of the present invention are also directed to the simultaneous cleaning and disinfecting of contact lenses, when compositions of the present invention are combined with a suitable disinfectant.
    Type: Grant
    Filed: March 19, 1997
    Date of Patent: February 9, 1999
    Assignee: Alcon Laboratories, Inc.
    Inventors: Joonsup Park, Ronald P. Quintana, Bor-shyue Hong, Bahram Asgharian
  • Patent number: 5723421
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: October 18, 1995
    Date of Patent: March 3, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth Ann Rosenthal
  • Patent number: 5718895
    Abstract: Compositions containing an ophthalmically acceptable, modified enzyme exhibiting a low pI and methods involving the combined use of these compositions with a polymeric antimicrobial agent, are disclosed for the simultaneous cleaning and disinfecting of contact lens.
    Type: Grant
    Filed: November 16, 1995
    Date of Patent: February 17, 1998
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bahram Asgharian, Bor-Shyue Hong, Ronald P. Quintana
  • Patent number: 5672213
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: August 18, 1995
    Date of Patent: September 30, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bahram Asgharian, Ronald P. Quintana, Bor-Shyue Hong
  • Patent number: 5654262
    Abstract: Compositions and methods are provided for cleaning and wetting of contact lenses, especially rigid, gas-permeable contact lenses. The compositions comprise low molecular weight polyalkylene oxide modified siloxanes, which are particularly effective in removing lipids from the surface of contact lenses.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: August 5, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Nayan N. Desai, Ronald P. Quintana, Masood A. Chowhan
  • Patent number: 5604190
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent, and complexing agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth A. Rosenthal
  • Patent number: 5532224
    Abstract: Compositions and methods are provided for cleaning and wetting of contact lenses, especially rigid, gas-permeable contact lenses. The compositions comprise low molecular weight polyalkylene oxide modified siloxanes, which are particularly effective in removing lipids from the surface of contact lenses.
    Type: Grant
    Filed: December 22, 1993
    Date of Patent: July 2, 1996
    Assignee: Alcon Laboratories, Inc.
    Inventors: Nayan N. Desai, Ronald P. Quintana, Masood A. Chowhan
  • Patent number: 5370744
    Abstract: An improved process for cleaning and disinfecting contact lenses with a single solution is described. The process utilizes the cleaning effect of a cleaning agent in combination with the solvent action of water and physical agitation of the lens (i.e., by means of rubbing) to achieve a degree of cleaning which is comparable to or better than prior processes which utilize surfactant-cleaners. The cleaning agent is selected from polycarboxylates, polysulfonates and polyphosphates. The preferred cleaning agent is citrate. The process also offers greater convenience, relative to many prior systems for cleaning and disinfecting contact lenses, since the need to utilize additional products to clean the lenses is eliminated.
    Type: Grant
    Filed: August 27, 1993
    Date of Patent: December 6, 1994
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood Chowhan, Thierry Bilbault, Ronald P. Quintana
  • Patent number: 4994462
    Abstract: This invention relates to certain N,N'-bis(nipecotyl)piperazines and their use as platelet aggregation inhibtory agents.
    Type: Grant
    Filed: October 5, 1988
    Date of Patent: February 19, 1991
    Assignee: Research Corporation
    Inventors: Andrew Lasslo, Ronald P. Quintana, Marion Dugdale, Randy W. Johnson
  • Patent number: 4798830
    Abstract: This invention relates to tetrahydroquinoline derivatives and their use for the inhibition of blood platelet aggregation.
    Type: Grant
    Filed: September 18, 1986
    Date of Patent: January 17, 1989
    Assignee: Research Corporation
    Inventors: Andrew Lasslo, Ronald P. Quintana, Marion Dugdale, Randy W. Johnson
  • Patent number: 4657917
    Abstract: A pharmaceutical composition in unit dosage form suitable for administration to an animal in need thereof comprising a pharmaceutically acceptable carrier and an amount sufficient to inhibit blood platelet aggregation of a compound selected from the group consisting of:[A] A compound having the structural formula: ##STR1## wherein R.sub.1 is ##STR2## R.sub.2 is H or ##STR3## and Alk is lower alkyl;[B] A compound having the structural formula: ##STR4## wherein when R.sub.3 is ##STR5## n is 8, and when R.sub.3 is ##STR6## n is 4 or 8, and Alk is lower alkyl;[C] A compound having the structural formula: ##STR7## wherein when R.sub.4 is ##STR8## n is 8, andwhen R.sub.4 is ##STR9## n is 0, 1, 4 or 8, and Alk is lower alkyl;[D] A compound having the structural formula: ##STR10## wherein Alk is lower alkyl; and[E] Addition salts thereof with pharmaceutically acceptable acids.
    Type: Grant
    Filed: October 18, 1984
    Date of Patent: April 14, 1987
    Assignee: Research Corporation
    Inventors: Andrew Lasslo, Ronald P. Quintana, Marion Dugdale
  • Patent number: 4634709
    Abstract: This invention relates to certain heterocyclic compounds which are useful as platelet inhibitory agents and intermediates for these compounds.
    Type: Grant
    Filed: January 16, 1984
    Date of Patent: January 6, 1987
    Assignee: Research Corporation
    Inventors: Andrew Lasslo, Ronald P. Quintana, Marion Dugdale, Randy W. Johnson
  • Patent number: 4443450
    Abstract: Various bis-nitrogen containing compounds exhibiting blood platelet aggregation inhibiting activity. One such compound being [substituted-N, N.sup.1 -Bis-(nipecotyl)]-piperazine.
    Type: Grant
    Filed: April 15, 1982
    Date of Patent: April 17, 1984
    Assignee: Research Corporation
    Inventors: Andrew Lasslo, Ronald P. Quintana, Marion Dugdale, Randy W. Johnson