Abstract: There is disclosed a toothbrush and paste cartridge assembly which includes a toothbrush formed by a handle having a hollow interior and terminating in a closed bristle portion at one end and being open at the opposed end, the toothbrush handle provided with an elongate slot extending along the length thereof, the slot provided with a plurality of pusher positioning nibs, pusher means reciprocally carried on the toothbrush adapted for travel along the length of the hollow interior, the pusher means provided with pusher stop means in cooperating relation with the pusher positioning nibs to permit positioning of the pusher means at a plurality of stop positions along the length of the handle, the hollow interior of the toothbrush including a chamfered section positioned adjacent to closed bristle end, the chamfered section in turn, terminating in a nozzle section, and the nozzle section being disposed arcuately in the direction of and in open communication with closed bristle portion of the toothbrush, in a pre