Abstract: A three valve cylinder head assembly includes a cylinder head mountable to an internal combustion engine. The cylinder head has a combustion chamber which has a sloped roof such that the combustion chamber has a wedge shape. Additionally, the cylinder head has an exhaust port and a pair of intake ports. An exhaust valve is movably integrated into the cylinder head for opening and closing the exhaust port. A pair of intake valves is each movably integrated into the cylinder head for opening and closing a respective one of the intake ports. A cam shaft is rotatably disposed on the cylinder head and the cam shaft engages the exhaust valve and each of the intake valves. The cam shaft sequentially opens the exhaust valve and each of the intake valves as the cam shaft rotates for supporting operation of the internal combustion engine.

Abstract: A smart trailer system coupled to a trailer of a vehicle includes a sensor configured to measure a parameter of the trailer, a sensor interface board electrically coupled to the sensor and configured to retrieve the measured parameter, and a master controller communicatively coupled to the sensor interface board via a data bus.

Abstract: A system and method are provided for quantifying greenhouse gas (GHG) emissions associated with vehicle traffic. The method includes receiving data from a plurality of devices located at a plurality of traffic intersections in a traffic network, each device comprising at least one sensor configured to obtain data from the corresponding traffic intersection; using the received data and a traffic model to determine vehicle trajectory data; using the vehicle trajectory data and an emissions model to obtain corresponding GHG emissions data; and evaluating the corresponding GHG emissions data to a baseline of GHG emissions using a GHG quantification methodology to determine a GHG reduction that can achieve a carbon offset credit.

Abstract: Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.

Abstract: A watercraft, associated motor pod, and associated methods are provided. The motor pod is operable to maintain an orientation of the watercraft relative to a reference datum while the watercraft is moving or stationary.

Abstract: Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.

Abstract: The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care.

Abstract: An apparatus for drilling a secondary borehole includes a whipstock assembly configured to be deployed in a primary borehole, the whipstock assembly including a whipstock ramp, and a drilling assembly connected to a borehole string. The drilling assembly includes a drill bit connected to an articulated string portion having a plurality of connected sections configured to move laterally with respect to one another, and the articulated string portion is configured to be diverted by the whipstock ramp in a lateral direction to initiate drilling of a secondary borehole from the primary borehole.

Abstract: The present application is generally directed to systems, methods, and devices for diagnostics for sensing and/or identifying pathogens, genomic materials, proteins, and/or other small molecules or biomarkers. In some implementations, a small footprint low cost device provides rapid and robust sensing and identification. Such a device may utilize microfluidics, biochemistry, and electronics to detect one or more targets at once in the field and closer to or at the point of care. In some implementations, the systems and methods herein implement a reader device, an assay cartridge, and a mobile or external device configured to receive abiological sample, test the biological sample, and provide test results to a patient or user associated with the patient. The test results may be packaged with additional information, including symptoms suffered by the patient, a diagnosis, and follow-up instructions.

Abstract: Some embodiments of the methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include performing a recombinase polymerase amplification (RPA) and, optionally, a second isothermal amplification reaction. In some embodiments, the second isothermal amplification reaction includes loop-mediated isothermal amplification (LAMP). In some embodiments, the second isothermal amplification reaction is performed in conjunction with the RPA. In some embodiments, the second isothermal amplification reaction is performed on amplification products of the RPA. Some embodiments also include detecting the presence of amplification products by measuring a modulation of an electoral signal such as impedance.

Abstract: Embodiments relate to methods, systems and compositions for reducing nonspecific amplification in isothermal amplification reactions. Some embodiments relate to reducing nonspecific amplification in loop-mediated isothermal amplification (LAMP) reactions with certain oligonucleotides.

Abstract: Some embodiments of the systems, devices, kits and methods provided herein relate to amplifying and detecting a target nucleic acid. Some such embodiments include a droplet comprising an aqueous reaction mixture and an oil, and a detection unit. Some embodiments include a passageway or conduit configured to transport the droplet. In some embodiments, the detection unit includes an electric field-generating unit and an electro-sensing element.

Abstract: An apparatus for drilling a secondary borehole includes a whipstock assembly configured to be deployed in a primary borehole, the whipstock assembly including a whipstock ramp, and a drilling assembly connected to a borehole string. The drilling assembly includes a drill bit connected to an articulated string portion having a plurality of connected sections configured to move laterally with respect to one another, and the articulated string portion is configured to be diverted by the whipstock ramp in a lateral direction to initiate drilling of a secondary borehole from the primary borehole.

Abstract: The invention provides a particle comprising a first semiconductor and a second semiconductor wherein the first semiconductor forms a heterojunction with the second semiconductor. The invention also provides a pharmaceutical composition comprising the particles, and relates to uses of the particles and composition in the treatment of cancer in combination with radiotherapy.

Abstract: Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.

Abstract: Embodiments provide analyte detection methods, techniques and processes for detecting the presence of one or more analytes in one or more samples. In a detection method, a sample and a sensor compound is introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of an analyte in the channel is determined based on a comparison between the first and second electrical property values.

Abstract: Embodiments provide detection systems and methods for detecting the presence of a nucleic acid in one or more samples. In a detection method, a sample and one or more nucleic acid probes are introduced into a channel. A first potential difference is applied across the length of the channel in a first direction, and a first electrical property value is detected. Subsequently, a second potential difference is applied across the length of the channel in a second opposite direction, and a second electrical property value is detected. Presence or absence of a nucleic acid in the channel is determined based on a comparison between the first and second electrical property values.

Abstract: A shallow water anchor and related methods are provided. The shallow water anchor includes a four-bar linkage and a hydraulic actuator for actuating the four-bar linkage. An anchoring element is connected to the four-bar linkage. A hydraulic control arrangement operates the hydraulic actuator to transition the hydraulic actuator between stowed and deployed positions and vice versa. The shallow water anchor can incorporate a controller which monitors a current limit, a pressure limit, or both to perform a variety of anchoring functions.