Patents by Inventor Ronald R. Notvest

Ronald R. Notvest has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzobicycloalkane derivatives as anticonvulsant neuroprotective agents
    Patent number: 4957909
    Abstract: The use of the compounds: ##STR1## where R is hydrogen, alkyl, alkoxy, hydroxy, alkanoyloxy, phenylalkoxy, halo or trifluoromethyl; R.sup.1 is alkyl, alkenyl or phenylalkyl; R.sup.2 is hydrogen, alkyl, phenylalkyl, alkenyl, alkynyl, thienylalkyl or furylalkyl; n is one of the integers 2, 3, 4, 5 or 6; or a pharmaceutically acceptable salt thereof, as NMDA antagonists in the treatment of convulsions and neurodegenerative disease states. The compounds in which R.sup.2 are heterocyclylalkylamines are novel and useful NMDA antagonists.
    Type: Grant
    Filed: January 2, 1990
    Date of Patent: September 18, 1990
    Assignee: American Home Products Corporation
    Inventors: Magid A. Abou-Gharbia, Ronald R. Notvest
  • Benzobicycloalkane derivatives as anticonvulsant neuroprotective agents
    Patent number: 4924008
    Abstract: The use of the compounds: ##STR1## where R is hydrogen, alkyl, alkoxy, hydroxy, alkanoyloxy, phenylalkoxy, halo or trifluoromethyl; R.sup.1 is alkyl, alkenyl or phenylalkyl; R.sup.2 is hydrogen, alkyl, phenylalkyl, alkenyl, alkynyl, thienylalkyl or furylalkyl; n is one of the integers 2, 3, 4, 5 or 6; or a pharmaceutically acceptable salt thereof, as NMDA antagonists in the treatment of convulsions and neurodegenerative disease states. The compounds in which R.sup.2 are heterocyclylalkylamines are novel and useful NMDA antagonists.
    Type: Grant
    Filed: May 4, 1989
    Date of Patent: May 8, 1990
    Assignee: American Home Products Corporation
    Inventors: Magid A. Abou-Gharbia, Ronald R. Notvest
  • Tolrestat for hearing impairment
    Patent number: 4783486
    Abstract: A method is disclosed for improving hearing by alleviating auditory nerve dysfunction by administering an effective amount of tolrestat.
    Type: Grant
    Filed: January 16, 1987
    Date of Patent: November 8, 1988
    Assignee: American Home Products Corporation
    Inventor: Ronald R. Notvest