Patents by Inventor Ronald R. Rasmussen

Ronald R. Rasmussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antifungal corynecandin
    Patent number: 5863773
    Abstract: Disclosed are novel antifungal agents having the formula: ##STR1## as well as a pharmaceutically acceptable salt, ester of prodrug thereof, whereinR is: ##STR2## --C(O)--R.sub.1 wherein R.sub.1 is alkyl, alkenyl, aryl, arylalkenyl, aryl-aryl-, arylalkoxy-aryl-, aryl-aryl-aryl-, arylkoxy-aryl-aryl-, or ##STR3## wherein R.sub.2 is alkylamino, dialkylamino, (heterocyclic)alkyl, aryl, or arylalkyl; andX is O, NH, or NR.sub.3 wherein R.sub.3 is alkyl or aryl. Also disclosed are pharmaceutical compositions comprising a compound of the invention in combination with a pharmaceutically acceptable carrier; and a process for preparing the compounds of the invention.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: January 26, 1999
    Assignee: Abbott Laboratories
    Inventors: Geewananda P. Gunawardana, David Frost, Marianna Jackson, James P. Karwowski, Ronald R. Rasmussen
  • Bromotiacumicin compounds
    Patent number: 5767096
    Abstract: Antimicrobial compounds having the formula ##STR1## wherein R.sup.1 and R.sup.2 are independently selected from the group consisting of hydrogen and C.sub.1 -to-C.sub.4 alkanoyl;R.sup.3 and R.sup.4 are selected from the group consisting of(a) R.sup.3 is hydrogen and R.sup.4 is hydroxy,(b) R.sup.3 is hydroxy and R.sup.4 is hydrogen,(c) R.sup.3 and R.sup.4 taken together are .dbd.O; or selected from the group consisting of hydrogen and hydroxy; andR.sup.5 and R.sup.6 are independently selected from the group consisting of hydrogen, bromine and chlorine, with the proviso that at least one of R.sup.5 and R.sup.6 must be bromine. Also disclosed are pharmaceutical compositions comprising such compounds, methods of treating bacterial infection by the administration thereof and a process for preparing said compounds.
    Type: Grant
    Filed: July 12, 1996
    Date of Patent: June 16, 1998
    Assignee: Abbott Laboratories
    Inventors: Jill E. Hochlowski, Marianna Jackson, James B. McAlpine, Ronald R. Rasmussen
  • Antifungal compounds
    Patent number: 5356933
    Abstract: Novel compounds having the structural formula ##STR1## and pharmaceutically acceptable salts and prodrugs thereof, wherein one of R.sup.1 and R.sup.2 is hydrogen and the other is --CH.dbd.CHCOOH, X is >CH--, and Y is --0--; or, alternatively, the bond between X and Y is not present, X is --CH.sub.2 --, and Y is --OH, as well as methods for their use, pharmaceutical compositions containing the same, and a process for their preparation via fermentation.
    Type: Grant
    Filed: June 28, 1993
    Date of Patent: October 18, 1994
    Assignee: Abbott Laboratories
    Inventors: Gregory M. Brill, James B. McAlpine, Ronald R. Rasmussen
  • Method for inhibiting nematode infection of plants with Nematostatic trichothecene compositions
    Patent number: 5030450
    Abstract: New trichothecene compositions are disclosed along with their use in methods of inhibiting nematode infection of plants.
    Type: Grant
    Filed: November 28, 1989
    Date of Patent: July 9, 1991
    Assignee: Abbott Laboratories
    Inventors: Premachandran Devidas, Ronald R. Rasmussen