Patents by Inventor Ronald Seubert

Ronald Seubert has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10416046
    Abstract: This disclosure is directed to a device and a system for picking a target analyte of a suspension. A picker introduces at least one force, such as by a magnetic gradient and/or by a pressure gradient, to extract the target analyte from a sample.
    Type: Grant
    Filed: June 13, 2017
    Date of Patent: September 17, 2019
    Assignee: RareCyte, Inc.
    Inventors: Joshua Nordberg, Steve Quarre, Ronald Seubert
  • Publication number: 20180364136
    Abstract: This disclosure is directed to a method and an attachment solution for adhering a cytological or histological sample, such as buffy coat, to a substrate, such as a microscope slide. The attachment solution includes an attachment base, an anti-coagulant, and a nonsteroidal anti-inflammatory drug. The attachment base may be an alcohol, an acid, an oxidizer, an organohalogen, a ketone, or any combination thereof. Once a sample is obtained, the sample may be re-suspended in the attachment solution or the attachment solution may be added to the sample. The sample may then be dispensed onto an analysis platform as one or more droplets and cured.
    Type: Application
    Filed: August 27, 2018
    Publication date: December 20, 2018
    Inventors: Daniel CAMPTON, Joshua NORDBERG, Ronald SEUBERT
  • Patent number: 10101248
    Abstract: This disclosure is directed to a method and an attachment solution for adhering a cytological or histological sample, such as buffy coat, to a substrate, such as a microscope slide. The attachment solution includes an attachment base, an anti-coagulant, and a nonsteroidal anti-inflammatory drug. The attachment base may be an alcohol, an acid, an oxidizer, an organohalogen, a ketone, or any combination thereof. Once a sample is obtained, the sample may be re-suspended in the attachment solution or the attachment solution may be added to the sample. The sample may then be dispensed onto an analysis platform as one or more droplets and cured.
    Type: Grant
    Filed: October 18, 2017
    Date of Patent: October 16, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Ronald Seubert
  • Patent number: 10101247
    Abstract: This disclosure is directed to a method and an attachment solution for adhering a cytological or histological sample, such as buffy coat, to a substrate, such as a microscope slide. The attachment solution includes an attachment base, an anti-coagulant, and a nonsteroidal anti-inflammatory drug. The attachment base may be an alcohol, an acid, an oxidizer, an organohalogen, a ketone, or any combination thereof. Once a sample is obtained, the sample may be re-suspended in the attachment solution or the attachment solution may be added to the sample. The sample may then be dispensed onto an analysis platform as one or more droplets and cured.
    Type: Grant
    Filed: December 2, 2015
    Date of Patent: October 16, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Ronald Seubert, Steve Quarre
  • Patent number: 10088392
    Abstract: This disclosure is directed to a device and a system for aspirating and dispensing a target analyte, target material, or fluid. A picker may aspirate and dispense the desired material by introducing a pressure gradient. The picker may include a hydraulic fluid to hydraulically couple at least two components, such as a moveable pump component and a cannula.
    Type: Grant
    Filed: April 11, 2017
    Date of Patent: October 2, 2018
    Assignee: RareCyte, Inc.
    Inventors: Joshua Nordberg, Steve Quarre, Ronald Seubert
  • Patent number: 10054524
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. An enrichment agent may be added to a vessel that contains the sample for positive selection, or, in other words, to select or aid in selecting the target material from amongst the remainder of the sample. The enrichment agent may be, for example, immunomagnetic beads, buoyant beads, high-density beads, chemicals to change the density of the target material, or the like.
    Type: Grant
    Filed: November 2, 2016
    Date of Patent: August 21, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Publication number: 20180221869
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving target material from a suspension. A system includes a processing vessel, a displacement fluid, and a tube. The tube includes a funnel, a cannula, and a cavity. The cannula allows for fluid communication between the funnel and the cavity, such that the processing vessel is inserted into the cavity, and the cannula extends into the processing vessel.
    Type: Application
    Filed: March 30, 2018
    Publication date: August 9, 2018
    Inventors: Lance U'REN, Ronald SEUBERT
  • Publication number: 20180202901
    Abstract: This disclosure is directed to a system and method for detecting a surface of a substrate within a scanner.
    Type: Application
    Filed: March 15, 2018
    Publication date: July 19, 2018
    Inventors: Paulina VARSHAVSKAYA, Edward SHAFER, Steve QUARRE, Ronald SEUBERT
  • Publication number: 20180195935
    Abstract: This disclosure is directed to a device and a system for aspirating and dispensing a target analyte, target material, or fluid. A picker may aspirate and dispense the desired material by introducing a pressure gradient. The picker may include a hydraulic fluid to hydraulically couple at least two components, such as a moveable pump component and a cannula.
    Type: Application
    Filed: April 11, 2017
    Publication date: July 12, 2018
    Applicant: RareCyte, Inc.
    Inventors: Joshua Nordberg, Steve Quarre, Ronald Seubert
  • Patent number: 9956555
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving target material from a suspension. A system includes a processing vessel, a displacement fluid, and a tube. The tube includes a funnel, a cannula, and a cavity. The cannula allows for fluid communication between the funnel and the cavity, such that the processing vessel is inserted into the cavity, and the cannula extends into the processing vessel.
    Type: Grant
    Filed: September 13, 2016
    Date of Patent: May 1, 2018
    Assignee: RareCyte, Inc.
    Inventors: Lance U'Ren, Ronald Seubert
  • Patent number: 9945839
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a displacement fluid, a collector, and a primary vessel. In another implementation, the system includes a processing vessel, a displacement fluid, a collector, and a primary vessel.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: April 17, 2018
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert
  • Patent number: 9810605
    Abstract: This disclosure is directed to a device and a system for picking a target analyte of a suspension. A picker introduces at least one force, such as by a magnetic gradient and/or by a pressure gradient, to extract the target analyte from a specimen. The magnetic gradient may be introduced by a magnet, such as a permanent magnet or an electromagnet, and the pressure gradient may be introduced by a pump which moves within a fluid-primed cannula to create the pressure gradient, thereby drawing the target analyte into the cannula. The picker may also expel the target analyte onto or into a substrate, such as a well plate, after the target analyte has been drawn into the picker by reversing the pressure gradient or removing the magnetic gradient.
    Type: Grant
    Filed: September 25, 2016
    Date of Patent: November 7, 2017
    Assignee: RareCyte, Inc.
    Inventors: Joshua Nordberg, Steve Quarre, Ronald Seubert
  • Publication number: 20170276575
    Abstract: This disclosure is directed to a device and a system for picking a target analyte of a suspension. A picker introduces at least one force, such as by a magnetic gradient and/or by a pressure gradient, to extract the target analyte from a sample.
    Type: Application
    Filed: June 13, 2017
    Publication date: September 28, 2017
    Applicant: RareCyte, Inc.
    Inventors: Joshua Nordberg, Steve Quarre, Ronald Seubert
  • Publication number: 20170219463
    Abstract: This disclosure is directed to a device and a system for aspirating and dispensing a target analyte, target material, or fluid. A picker may aspirate and dispense the desired material by introducing a pressure gradient. The picker may include a hydraulic fluid to hydraulically couple at least two components, such as a moveable pump component and a cannula.
    Type: Application
    Filed: April 11, 2017
    Publication date: August 3, 2017
    Applicant: RareCyte, Inc.
    Inventors: Joshua Nordberg, Steve Quarre, Ronald Seubert
  • Publication number: 20170191911
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a plurality of processing vessels and a collector. The collector funnels portions of the target material from the suspension through a cannula and into the processing vessels. Sequential density fractionation is the division of a sample into fractions or of a fraction of a sample into sub-fractions by a step-wise or sequential process, such that each step or sequence results in the collection or separation of a different fraction or sub-fraction from the preceding and successive steps or sequences. In other words, sequential density fractionation provides individual sub-populations of a population or individual sub-sub-populations of a sub-population of a population through a series of steps.
    Type: Application
    Filed: January 8, 2017
    Publication date: July 6, 2017
    Applicant: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, Ronald Seubert, Jonathan Lundt, Lance U'Ren
  • Publication number: 20170074759
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. An enrichment agent may be added to a vessel that contains the sample for positive selection, or, in other words, to select or aid in selecting the target material from amongst the remainder of the sample. The enrichment agent may be, for example, immunomagnetic beads, buoyant beads, high-density beads, chemicals to change the density of the target material, or the like.
    Type: Application
    Filed: November 2, 2016
    Publication date: March 16, 2017
    Applicant: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Publication number: 20170059552
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a displacement fluid, a collector, and a primary vessel. In another implementation, the system includes a processing vessel, a displacement fluid, a collector, and a primary vessel.
    Type: Application
    Filed: November 14, 2016
    Publication date: March 2, 2017
    Applicant: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert
  • Publication number: 20170014819
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving target material from a suspension. A system includes a processing vessel, a displacement fluid, and a tube. The tube includes a funnel, a cannula, and a cavity. The cannula allows for fluid communication between the funnel and the cavity, such that the processing vessel is inserted into the cavity, and the cannula extends into the processing vessel.
    Type: Application
    Filed: September 13, 2016
    Publication date: January 19, 2017
    Applicant: RareCyte, Inc.
    Inventors: Lance U'Ren, Ronald Seubert
  • Patent number: 9541481
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a sample. A first depletion agent may be added to a vessel that contains the sample to change the density of a non-target material.
    Type: Grant
    Filed: June 5, 2016
    Date of Patent: January 10, 2017
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren, Jennifer Chow
  • Patent number: 9533303
    Abstract: This disclosure is directed to an apparatus, system and method for retrieving a target material from a suspension. A system includes a primary vessel, such as a tube, a collector, and a two-part seal including an internal pliant part and an external constricting part. The internal pliant part may be a float and the external constricting part may be a sealing ring. The system may also include a processing vessel, such as an Eppendorf tube, a syringe or a test tube. The collector is sized and shaped to fit into a primary vessel and funnels the target material from the suspension through a cannula and into the processing vessel. In one implementation, the processing vessel includes at least one displacement fluid to be expelled, such that the at least one displacement fluid pushes the target material into the collector.
    Type: Grant
    Filed: May 7, 2015
    Date of Patent: January 3, 2017
    Assignee: RareCyte, Inc.
    Inventors: Daniel Campton, Joshua Nordberg, Steve Quarre, David Stewart, Ronald Seubert, Jonathan Lundt, Lance U'Ren