Abstract: The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative breast disease as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative breast disease as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative breast disease who is at risk of developing breast cancer. The invention also provides kits for performing the above methods.

Abstract: The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative disease of the endometrium or ovary as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative disease of the endometrium or ovary as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative disease of the endometrium or ovary who is at risk of developing endometrial or ovarian cancer. The invention also provides kits for performing the above methods.

Abstract: The present invention relates to an in-vitro method of identifying a tumor resulting from a proliferative breast disease as responsive to anti-estrogen treatment. Further, the invention relates to an in-vitro method of identifying a candidate patient with a proliferative breast disease as suitable for anti-estrogen treatment. In a further aspect, the invention provides an in-vitro method of identifying an individual with a non-cancerous proliferative breast disease who is at risk of developing breast cancer. The invention also provides kits for performing the above methods.

Abstract: A folding walker with side frames rotationally mounted on both ends of a front frame such that the side frames can rotate independently from a closed position where they are parallel to the front frame to an open position where the side frames are perpendicular to the front frame and parallel to each other. The side frames are locked in the open position by fixed plates that are mounted on the front frame. Detents with lever releases are mounted on the side frames. The detents releasably engage the fixed plates when the side frames are in the open position.

Abstract: The tool includes a tool head having a tapered portion at one end for receipt within the flexible snap ring of a filter bag for expanding the snap ring into seating and sealing engagement about the margins of the opening in the tube sheet to secure the filter bag in depending relation from the tube sheet. The tool also includes a slidable member or weight along its handle whereby, in the event the tool becomes stuck in the opening, the weight can be displaced upwardly to impact against a tool surface and thus jar the tool loose from its engagement with the snap ring.