Abstract: Methods for packaging a pressure or vacuum sensitive product, such as an ultrasound contrast media comprised of a gas-filled microshpere or microbubble, or sealing such a product in a single-compartment syringe, in a manner that does not utilize pressure or vacuum in the process, are provided.

Abstract: A delivery apparatus for delivering various media, such as medical and/or pharmaceutical media or the like, from a delivery device, such as a syringe, in which the delivery pressure of the medium as it is dispensed from the delivery device is automatically maintained and regulated at a preselected level throughout delivery of the medium from the delivery apparatus. In one embodiment, the skin temperature of the patient is also sensed and the pressure of the medium being administered to the patient is further adjusted in response to the sensed skin temperature.

Abstract: A pressure monitoring device for indicating to the administrator of an injection to a patient that an excess of force has been exerted on the plunger and thereby the fluids contained within the syringe.