Patents by Inventor Ronald Wolin

Ronald Wolin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aryl Piperidine Amides
    Publication number: 20080009521
    Abstract: The invention provides novel GlyT2 inhibiting compounds useful in modulating, treating, or preventing: anxiolytic disorders; a condition requiring treatment of injured mammalian nerve tissue; a condition amenable to treatment through administration of a neurotrophic factor; a neurological disorder; or obesity; an obesity-related disorder.
    Type: Application
    Filed: July 19, 2007
    Publication date: January 10, 2008
    Inventors: Charles Huang, Timothy Lovenberg, Alejandro Santillan, Liu Tang, Ronald Wolin
  • HEXAHYDRO-PYRROLO-ISOQUINOLINE COMPOUNDS
    Publication number: 20060293316
    Abstract: Certain hexahydro-pyrrolo-isoquinoline compounds are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases.
    Type: Application
    Filed: June 16, 2006
    Publication date: December 28, 2006
    Inventors: Richard Apodaca, Ann Barbier, Nicholas Carruthers, Leslie Gomez, John Keith, Timothy Lovenberg, Ronald Wolin
  • Tetrahydroisoquinoline compounds
    Publication number: 20060194837
    Abstract: Certain tetrahydroisoquinoline compounds are histamine H3 receptor and serotonin transporter modulators useful in the treatment of histamine H3 receptor- and serotonin-mediated diseases.
    Type: Application
    Filed: December 15, 2005
    Publication date: August 31, 2006
    Inventors: Nicholas Carruthers, Leslie Gomez, Jill Jablonowski, John Keith, Michael Letavic, Kiev Ly, Jennifer Miller, Emily Stocking, Ronald Wolin
  • Cannabinoid receptor ligands
    Publication number: 20060009528
    Abstract: There are disclosed compounds of the formula a prodrug thereof, or a pharmaceutically acceptable salt, solvate or stereoisomer of the compound or of said prodrug; which exhibit anti-inflammatory and immunodulatory activity. Also disclosed are pharmaceutical compositions containing said compounds and methods of using the compounds for the treatment of various diseases and conditions.
    Type: Application
    Filed: August 15, 2005
    Publication date: January 12, 2006
    Inventors: Joseph Kozlowski, Neng-Yang Shih, Brian Lavey, Razia Rizvi, Bandarpalle Shankar, James Spitler, Ling Tong, Ronald Wolin, Michael Wong
  • GlyT2 modulators
    Publication number: 20050119245
    Abstract: Certain ?-, ?-, and ?-amino acid derivatives are disclosed as selective GlyT2 inhibitors for the treatment of central nervous system (CNS) conditions such as muscle spasticity, tinnitus, epilepsy and neuropathic pain.
    Type: Application
    Filed: October 28, 2004
    Publication date: June 2, 2005
    Inventors: Tristin Barclay, Alejandro Santillan, Liu Tang, Hariharan Venkatesan, Ronald Wolin
  • Phenyl-substituted imidazopyridines
    Publication number: 20050090523
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 28, 2005
    Inventors: J. Breitenbucher, Nicholas Carruthers, Xiaobing Li, Laura McAtee, Chandravadan Shah, Ronald Wolin
  • Phenyl-substituted imidazopyridines
    Publication number: 20050085502
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 21, 2005
    Inventors: J. Breitenbucher, Nicholas Carruthers, Xiaobing Li, Laura McAtee, Chandravadan Shah, Ronald Wolin
  • Phenyl-substituted imidazopyridines
    Publication number: 20050085501
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Application
    Filed: October 7, 2004
    Publication date: April 21, 2005
    Inventors: J. Breitenbucher, Nicholas Carruthers, Xiaobing Li, Laura McAtee, Chandravadan Shah, Ronald Wolin
  • Phenyl-substituted imidazopyridines
    Publication number: 20050049277
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Application
    Filed: October 7, 2004
    Publication date: March 3, 2005
    Inventors: J. Breitenbucher, Nicholas Carruthers, Xiaobing Li, Laura McAtee, Chandravadan Shah, Ronald Wolin
  • Aryl piperidine amides
    Publication number: 20050049239
    Abstract: The invention provides novel GlyT2 inhibiting compounds useful in modulating, treating, or preventing: anxiolytic disorders; a condition requiring treatment of injured mammalian nerve tissue; a condition amenable to treatment through administration of a neurotrophic factor; a neurological disorder; or obesity; an obesity-related disorder.
    Type: Application
    Filed: August 17, 2004
    Publication date: March 3, 2005
    Inventors: Charles Huang, Timothy Lovenberg, Alejandro Santillan, Liu Tang, Ronald Wolin
  • Phenyl-substituted imidazopyridines
    Publication number: 20050043348
    Abstract: The invention features pharmaceutically-active imidazopyridines and derivatives that are substituted with phenyl, methods of making them, and methods of using them.
    Type: Application
    Filed: October 7, 2004
    Publication date: February 24, 2005
    Inventors: J. Breitenbucher, Nicholas Carruthers, Xiaobing Li, Laura McAtee, Chandravadan Shah, Ronald Wolin
  • Substituted imidazoles as dual histamine H1 and H3 agonists or antagonists
    Patent number: 6762186
    Abstract: The present invention discloses novel substituted imidazole compounds which have H3 receptor antagonist or dual histamine-H1 and H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such imidazoles as well as methods of using them to treat allergy, nasal congestion, inflammatory and CNS-related diseases and others.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: July 13, 2004
    Assignee: Schering Corporation
    Inventors: Neng-Yang Shih, Robert G. Aslanian, Daniel M. Solomon, Stuart B. Rosenblum, Mwangi Wa Mutahi, Tom G. Wing, Kevin D. McCormick, John J. Piwinski, Ronald Wolin
  • Substituted imidazoles as dual histamine H1 and H3 agonists or antagonists
    Publication number: 20020082278
    Abstract: The present invention discloses novel substituted imidazole compounds which have H3 receptor antagonist or dual histamine-H1 and H3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such imidazoles as well as methods of using them to treat allergy, nasal congestion, inflammatory and CNS-related diseases and others.
    Type: Application
    Filed: September 18, 2001
    Publication date: June 27, 2002
    Inventors: Neng-Yang Shih, Robert G. Aslanian, Daniel M. Solomon, Stuart B. Rosenblum, Mwangi Wa Mutahi, Wing C. Tom, Kevin D. Mc Cormick, John J. Piwinski, Ronald Wolin
  • N-(imidazolylalkyl)substituted cyclic amines as histamine-H.sub.3 agonists or antagonists
    Patent number: 6133291
    Abstract: The present invention discloses novel N(imidazolylalkyl)-substituted cyclic amine compounds which have excellent histamine-H.sub.3 receptor antagonist activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such cyclic amines as well as methods of using them to treat allergy, inflammatory and CNS-related diseases.
    Type: Grant
    Filed: October 16, 1998
    Date of Patent: October 17, 2000
    Assignee: Schering Corporation
    Inventors: Ronald Wolin, Stuart B. Rosenblum, Adriano Afonso