Patents by Inventor Ronaldo A.P. Nagem

Ronaldo A.P. Nagem has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crystal structure of interleukin-22 and uses thereof
    Publication number: 20040002586
    Abstract: This invention provides the three dimensional structure of human IL-22 and recombinant human IL-22 with mutations in the receptor binding regions and the dimerization interface and nucleic acid molecule encoding same. This invention also relates to methods of using pharmaceutical formulations and mimetics of the recombinant IL-22 and to methods for generating mutants based on the crystalline structure of IL-22.
    Type: Application
    Filed: September 10, 2002
    Publication date: January 1, 2004
    Inventors: Ronaldo A.P. Nagem, Igor Polikarpov, Jean Christophe Renauld, Didier Colau, Laure Dumoutier