Patents by Inventor Ronaldo C. Cayabyab

Ronaldo C. Cayabyab has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210085458
    Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.
    Type: Application
    Filed: December 3, 2020
    Publication date: March 25, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Ronaldo C. Cayabyab, David J. Evans, Sean Chow, Christopher Chia, Tamir S. Levi
  • Publication number: 20210030540
    Abstract: Embodiments of the present disclosure provide an introducer device and method for introducing a delivery apparatus into a patient's vasculature. Disclosed methods can include positioning a sleeve of an introducer sheath in a blood vessel of a patient, the sleeve having a lattice layer with a lumen therethrough, inserting a distal end portion of the delivery apparatus and a prosthetic heart valve into the lumen, and advancing the distal end portion of the delivery apparatus through the lumen from the proximal end to the distal end. The method can then include expanding the lumen from a first diameter smaller to a second diameter at least equal to the diameter of the prosthetic heart valve to allow passage of the prosthetic heart valve through the lumen, and returning the lumen of the sleeve to a diameter smaller than the second diameter after advancing the prosthetic heart valve through the lumen.
    Type: Application
    Filed: October 16, 2020
    Publication date: February 4, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes
  • Publication number: 20210001090
    Abstract: In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion and a distal portion, and first and second pull wires having respective proximal portions and respective distal portions. The proximal portions of the first and second pull wires extend through the proximal portion of the shaft in close proximity to each other. The distal portions of the first and second pull wires extend through the distal portion of the shaft in close proximity to each other over a first distance defining a primary flexing section, diverge away from each other over a second distance, and then extend parallel to each other at angularly spaced locations over a third distance defining a secondary flexing section.
    Type: Application
    Filed: September 21, 2020
    Publication date: January 7, 2021
    Applicant: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Sean Chow, Ronaldo C. Cayabyab
  • Publication number: 20200397574
    Abstract: Embodiments of the present disclosure provide a delivery apparatus for a prosthetic heart valve. Disclosed delivery apparatuses can include a housing, a steerable shaft, a slide nut, and a threaded shaft disposed over the slide nut. The slide nut can have an external threaded surface and an internal surface comprising a slot. The threaded shaft can have an internal threaded surface engaging the external threaded surface of the slide nut. The delivery apparatus can further include an elongated nut guide extending into the slot of the nut to restrain the slide nut against rotation relative to the housing, and a pull wire having a proximal end portion extending into the housing and coupled to the slide nut, and a distal end portion coupled to a distal end portion of the steerable shaft. The threaded shaft can be rotatable relative to the housing to produce axial movement of the slide nut within the threaded shaft.
    Type: Application
    Filed: September 8, 2020
    Publication date: December 24, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes
  • Publication number: 20200390549
    Abstract: Embodiments of the present disclosure provide an introducer device and methods for introducing a medical device into a patient's vasculature. In one embodiment, a method of using an introducer device including a housing, a hemostatic seal mounted within the housing, and a tube extending into the housing and movable longitudinally relative to the hemostatic seal between a proximal position and a distal position, includes moving the tube to the distal position such that the distal end of the tube extends through the hemostatic seal. The method further includes inserting a distal end portion of the medical device through the tube and into the patient's vasculature without contacting the hemostatic seal.
    Type: Application
    Filed: August 26, 2020
    Publication date: December 17, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes
  • Patent number: 10856977
    Abstract: A delivery apparatus for a prosthetic heart valve includes a shaft, an inner balloon, and an outer balloon. The shaft has a lumen extending from a proximal end portion to a distal end portion and a plurality of openings formed in the distal end portion. The shaft is configured such that a fluid can flow through the lumen and the openings. The inner balloon has end portions and a center portion disposed between the end portions. The inner balloon is mounted on the distal end portion of the shaft and is in fluid communication with the openings of the shaft. When the inner balloon is inflated with the fluid, the end portions expand farther radially outwardly than the center portion. The outer balloon is mounted to the shaft and disposed over the inner balloon. The outer balloon is configured to fully expand after the inner balloon at least partially expands.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: December 8, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Ronaldo C. Cayabyab, David J. Evans, Sean Chow, Christopher Chia, Tamir S. Levi
  • Publication number: 20200375735
    Abstract: Embodiments of the present disclosure provide a delivery apparatus for a prosthetic heart valve. Disclosed steerable catheters can include a handle, a steerable shaft extending from the handle, and a pull wire. The shaft can include a main lumen, an inner polymeric layer surrounding the main lumen, a braided layer surrounding the inner polymeric layer, and an outer polymeric layer surrounding the braided layer, the outer polymeric layer defining a pull wire lumen. The pull wire can extend from the handle and through the pull wire lumen and can have a distal end portion coupled to a distal end portion of the shaft.
    Type: Application
    Filed: August 17, 2020
    Publication date: December 3, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes
  • Publication number: 20200368021
    Abstract: Embodiments of the present disclosure provide a delivery apparatus for a prosthetic heart valve. Disclosed delivery apparatuses can include a handle, a first shaft extending from the handle, a second shaft disposed around the first shaft, and a valve cover. The valve cover can be coupled to a distal end portion of the first shaft and can be configured to house a prosthetic heart valve in a radially compressed state. The valve cover can have an outer diameter greater than an outer diameter of the second shaft, and the first shaft and valve cover can be movable together in an axial direction relative to the second shaft.
    Type: Application
    Filed: August 12, 2020
    Publication date: November 26, 2020
    Applicant: Edwards Lifesciences Corporation
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes
  • Patent number: 10792467
    Abstract: In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion, a distal portion, and a pull-wire lumen that extends at least partially through the proximal and distal portions. A pull wire extends through the pull-wire lumen and has a proximal end portion and a distal end portion, wherein the distal end portion of pull wire is fixed to the distal end portion of the shaft. An adjustment mechanism is operatively connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the distal portion of the shaft. An axially non-compressible pull-wire sleeve extends co-axially through the pull-wire lumen and over the pull wire.
    Type: Grant
    Filed: September 11, 2018
    Date of Patent: October 6, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Tri D. Tran, Sean Chow, Ronaldo C. Cayabyab
  • Publication number: 20200060822
    Abstract: A method of delivery a prosthetic heart valve includes inserting a delivery apparatus and a prosthetic heart valve into a patient's vasculature. The delivery apparatus includes a steerable guide catheter, a balloon catheter, and a flex indicator. The balloon catheter extends coaxially through the guide catheter, the prosthetic heart valve is mounted on a distal end portion of the balloon catheter, and the flex indicator is movably coupled to a handle of the guide catheter. The method further includes adjusting flexion of a steerable section of the guide catheter to position the prosthetic heart valve. The flex indicator moves relative to the handle of the guide catheter as the flexion of the steerable section is adjusted, and the handle comprises one or more visual indicators adjacent the flex indicator to provide visual indication of an amount of flexion of the steerable section of the guide catheter.
    Type: Application
    Filed: October 30, 2019
    Publication date: February 27, 2020
    Inventors: Thanh Huy Le, Tri D. Tran, Ronaldo C. Cayabyab, David M. Taylor, Antonio O. Vidal, Robert Bowes, Tram Ngoc Nguyen, Walter Lee
  • Patent number: 10478296
    Abstract: An apparatus for delivering a prosthetic heart valve includes a steerable guide catheter, a balloon catheter, and a flex indicator. The guide catheter has a handle and a guide tube extending from the handle. The guide tube has a distal end portion comprising a steerable section. The guide catheter further includes an adjustment mechanism on the handle and a pull wire connecting the adjustment mechanism to the steerable section for changing flexion of the steerable section. The balloon catheter includes a shaft extending coaxially through the guide tube. The shaft includes a proximal end portion and a distal end portion. The balloon catheter further includes a balloon mounted on the distal end portion of the shaft. The flex indicator moves relative to the handle upon adjustment of the adjustment mechanism. The handle includes visual indicia adjacent the flex indicator to provide visual indication of the flexion of the steerable section.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: November 19, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Thanh Huy Le, Tri D. Tran, Ronaldo C. Cayabyab, David M. Taylor, Antonio O. Vidal, Robert Bowes
  • Patent number: 10456253
    Abstract: A heart valve delivery apparatus includes a valve carrying member. A prosthetic valve is crimped onto the valve carrying member at a location that is distal or proximal to the balloon member, thereby providing a smaller profile delivery apparatus.
    Type: Grant
    Filed: June 10, 2015
    Date of Patent: October 29, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Thanh Huy Le, Tri D. Tran, Ronaldo C. Cayabyab, David M. Taylor, Antonio O. Vidal, Robert Bowes
  • Patent number: 10441419
    Abstract: A method of delivery a prosthetic heart valve includes inserting a delivery apparatus and a prosthetic heart valve into a patient's vasculature. The delivery apparatus includes a steerable guide catheter, a balloon catheter, and a flex indicator. The balloon catheter extends coaxially through the guide catheter, the prosthetic heart valve is mounted on a distal end portion of the balloon catheter, and the flex indicator is movably coupled to a handle of the guide catheter. The method further includes adjusting flexion of a steerable section of the guide catheter to position the prosthetic heart valve. The flex indicator moves relative to the handle of the guide catheter as the flexion of the steerable section is adjusted, and the handle comprises one or more visual indicators adjacent the flex indicator to provide visual indication of an amount of flexion of the steerable section of the guide catheter.
    Type: Grant
    Filed: November 20, 2018
    Date of Patent: October 15, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Thanh Huy Le, Tri D. Tran, Ronaldo C. Cayabyab, David M. Taylor, Antonio O. Vidal, Robert Bowes
  • Patent number: 10278815
    Abstract: An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent. The delivery apparatus has a handle, a first shaft having a proximal end portion and a distal end portion, a second shaft extending co-axially through the first shaft and having a proximal end portion and a distal end portion, the proximal end portions of the first and second shafts extending distally from the handle, a valve cover coupled to the distal end portion of the first shaft, and a nose piece coupled to the distal end portion of the second shaft.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: May 7, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes
  • Publication number: 20190110895
    Abstract: Embodiments of the present disclosure provide an introducer device for introducing a medical device into a patient's vasculature. In one embodiment, the introducer device comprises a housing, a distal sheath adapted to be inserted into a patient's vasculature with the housing positioned outside of the patient's vasculature, a hemostatic seal mounted within the housing, and a tube positioned within the housing and movable longitudinally relative to the hemostatic seal between a proximal position and a distal position. In the proximal position, a distal end of the tube is positioned proximal to the hemostatic seal with the hemostatic seal closed. In the distal position, the distal end of the tube extends through the hemostatic seal and permits the medical device to be inserted through the housing and into the patient's vasculature without contacting the hemostatic seal.
    Type: Application
    Filed: December 11, 2018
    Publication date: April 18, 2019
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes
  • Publication number: 20190083259
    Abstract: An apparatus for delivering a prosthetic heart valve includes a steerable guide catheter, a balloon catheter, and a flex indicator. The guide catheter has a handle and a guide tube extending from the handle. The guide tube has a distal end portion comprising a steerable section. The guide catheter further includes an adjustment mechanism on the handle and a pull wire connecting the adjustment mechanism to the steerable section for changing flexion of the steerable section. The balloon catheter includes a shaft extending coaxially through the guide tube. The shaft includes a proximal end portion and a distal end portion. The balloon catheter further includes a balloon mounted on the distal end portion of the shaft. The flex indicator moves relative to the handle upon adjustment of the adjustment mechanism. The handle includes visual indicia adjacent the flex indicator to provide visual indication of the flexion of the steerable section.
    Type: Application
    Filed: November 20, 2018
    Publication date: March 21, 2019
    Applicant: Edwards Lifesciences Corporation
    Inventors: Thanh Huy Le, Tri D. Tran, Ronaldo C. Cayabyab, David M. Taylor, Antonio O. Vidal, Robert Bowes
  • Publication number: 20190083260
    Abstract: A method of delivery a prosthetic heart valve includes inserting a delivery apparatus and a prosthetic heart valve into a patient's vasculature. The delivery apparatus includes a steerable guide catheter, a balloon catheter, and a flex indicator. The balloon catheter extends coaxially through the guide catheter, the prosthetic heart valve is mounted on a distal end portion of the balloon catheter, and the flex indicator is movably coupled to a handle of the guide catheter. The method further includes adjusting flexion of a steerable section of the guide catheter to position the prosthetic heart valve. The flex indicator moves relative to the handle of the guide catheter as the flexion of the steerable section is adjusted, and the handle comprises one or more visual indicators adjacent the flex indicator to provide visual indication of an amount of flexion of the steerable section of the guide catheter.
    Type: Application
    Filed: November 20, 2018
    Publication date: March 21, 2019
    Applicant: Edwards Lifesciences Corporation
    Inventors: Thanh Huy Le, Tri D. Tran, Ronaldo C. Cayabyab, David M. Taylor, Antonio O. Vidal, Robert Bowes
  • Patent number: 10179048
    Abstract: Embodiments of the present disclosure provide a delivery apparatus for delivering a prosthetic heart valve to a native valve site via the human vasculature without the need for a separate introducer sheath. The delivery apparatus is particularly well-suited for advancing a prosthetic valve through the aorta (i.e., in a retrograde approach) for replacing a stenotic aortic valve.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: January 15, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes
  • Publication number: 20190009061
    Abstract: In one representative embodiment, a steerable catheter device comprises a shaft comprising a proximal portion, a distal portion, and a pull-wire lumen that extends at least partially through the proximal and distal portions. A pull wire extends through the pull-wire lumen and has a proximal end portion and a distal end portion, wherein the distal end portion of pull wire is fixed to the distal end portion of the shaft. An adjustment mechanism is operatively connected to the proximal end portion of the pull wire and configured to increase and decrease tension in the pull wire to adjust the curvature of the distal portion of the shaft. An axially non-compressible pull-wire sleeve extends co-axially through the pull-wire lumen and over the pull wire.
    Type: Application
    Filed: September 11, 2018
    Publication date: January 10, 2019
    Inventors: Tri D. Tran, Sean Chow, Ronaldo C. Cayabyab
  • Publication number: 20180303608
    Abstract: An assembly includes a prosthetic heart valve and a delivery apparatus for implanting the prosthetic heart valve within the native aortic valve of a patient. The prosthetic heart valve has a radially compressible and expandable metallic stent and a flexible valvular structure mounted within the stent. The delivery apparatus has a handle, a first shaft having a proximal end portion and a distal end portion, a second shaft extending co-axially through the first shaft and having a proximal end portion and a distal end portion, the proximal end portions of the first and second shafts extending distally from the handle, a valve cover coupled to the distal end portion of the first shaft, and a nose piece coupled to the distal end portion of the second shaft.
    Type: Application
    Filed: June 25, 2018
    Publication date: October 25, 2018
    Inventors: Philippe Marchand, David M. Taylor, Robert Milich, David J. Evans, Christopher Chia, Ronaldo C. Cayabyab, Robert Bowes