Patents by Inventor Ronan MacLoughlin
Ronan MacLoughlin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11918731Abstract: An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes. A controller couples to the aerosol generator, the pump, and the breath sensor. In operation, the controller receives the signal from the breath sensor, controls a flow of fluid to the aerosol generator in response to the signal, and controls the aerosol generator to start aerosolizing the fluid before the patient inhales.Type: GrantFiled: May 28, 2021Date of Patent: March 5, 2024Assignee: Stamford Devices Ltd.Inventors: Shaun Porter, Louise Sweeney, Ronan MacLoughlin, Jim Fink, Aidan Duffy, Claire Lillis, Conor Duffy, Fran Keating
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Publication number: 20240066258Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.Type: ApplicationFiled: October 26, 2023Publication date: February 29, 2024Applicant: Stamford Devices LimitedInventors: Ronan MACLOUGHLIN, Niall SMITH
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Patent number: 11833310Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.Type: GrantFiled: January 23, 2020Date of Patent: December 5, 2023Assignee: Stamford Devices LimitedInventors: Ronan MacLoughlin, Niall Smith
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Publication number: 20230182162Abstract: A method for aerosolising a liquid comprises the steps of: —providing an aperture plate having at least 100 outlet holes per mm; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 to 15 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.Type: ApplicationFiled: October 11, 2022Publication date: June 15, 2023Applicant: Stamford Devices LimitedInventors: Ronan MACLOUGHLIN, Conor Paul DUFFY, Brendan HOGAN, Patrick Martin KELLY
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Publication number: 20230133932Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.Type: ApplicationFiled: December 5, 2022Publication date: May 4, 2023Applicant: STAMFORD DEVICES LIMITEDInventors: Ronan MACLOUGHLIN, Shaun PORTER, Conor DUFFY, John POWER
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Patent number: 11534570Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.Type: GrantFiled: July 3, 2018Date of Patent: December 27, 2022Assignee: Stamford Devices LimitedInventors: Ronan MacLoughlin, Shaun Porter, Conor Duffy, John Power
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Patent number: 11413407Abstract: An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient. The aerosol generator includes a housing with a fluid chamber that fluidly communicates with a housing inlet and a housing outlet. Within the housing, the aerosol generator includes a support plate with an aperture that fluidly communicates with the housing outlet. A vibratable member couples to the support plate across the aperture. A piezoelectric actuator also couples to the support plate, and in operation expands and contracts to vibrate the vibratable member, which aerosolizes a fluid. The aerosol generator receives fluid through a fluid conduit that couples to the housing.Type: GrantFiled: March 22, 2018Date of Patent: August 16, 2022Assignee: STAMFORD DEVICES LTD.Inventors: Shaun Porter, Louise Sweeney, Ronan MacLoughlin, Jim Fink, Aidan Duffy, Claire Lillis, Conor Duffy, Fran Keating
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Patent number: 11273271Abstract: In one aspect, embodiments of the present invention provide an aerosolization device for ensuring proper delivery of an aerosolized medication to a user's respiratory system. The aerosolization device may include a conduit, an aerosol generator, a restrictor disposed within the conduit, and an indicator mechanism. The conduit may include a mouthpiece end by which a user may cause inspiratory flow through the conduit. The aerosol generator may include a vibratable mesh. The restrictor may define a plurality of apertures disposed along an outer periphery of the restrictor configured to provide an increase in pressure differential that varies with an inspiratory flow rate within the conduit and to provide a relatively laminar flow downstream of the restrictor compared to upstream of the restrictor. The indicator mechanism may indicate to a user a state of a parameter of the inspiratory flow relative to a predefined desired range.Type: GrantFiled: August 7, 2017Date of Patent: March 15, 2022Assignee: Aerami Therapeutics, Inc.Inventors: Jim Fink, Lisa Molloy, Ronan MacLoughlin, Claire Elizabeth Lillis, Michael Joseph Casey, John Matthew Mullins, Kieran James Hyland, Joseph Martin Grehan
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Publication number: 20220016365Abstract: A dispensing apparatus is for use by users to take a chamber, fill the chamber with an aerosolized vaccine or other medicament, and dispose of used chambers. A display provides instructions to encourage prompt inhalation by the user from a dispensed and filled chamber. The apparatus allows very fast administration of vaccines to large numbers of people. The aerosol dispenser apparatus detects the chamber is in correct position and delivers a pre-determined dose of aerosol. Once the dose is delivered a visual and/or audible indicator informs the user that the chamber is filled and that they can take the inhalation. The single dose aerosol chamber is optimized for efficient administration of an aerosol.Type: ApplicationFiled: July 9, 2021Publication date: January 20, 2022Applicant: Stamford Devices LimitedInventors: John POWER, Ronan MacLOUGHLIN, Michael CASEY, Conor DUFFY, Aidan DUFFY
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Publication number: 20220016360Abstract: A single dose aerosol chamber is used with a dispensing apparatus by users to take a chamber, fill the chamber with an aerosolized vaccine, and dispose of used chambers. A display provides instructions to encourage prompt inhalation by the user from a dispensed and filled chamber. The station allows very fast administration of vaccines to large numbers of people. The aerosol dispenser apparatus detects the chamber is in correct position and delivers a pre-determined dose of aerosol. The chamber has a nebulizer delivery port optimized for delivery of aerosol into the chamber container and to act as a vent during inhalation via the inhalation port.Type: ApplicationFiled: July 9, 2021Publication date: January 20, 2022Applicant: Stamford Devices LimitedInventors: John POWER, Ronan MacLOUGHLIN, Michael CASEY, Conor DUFFY, Aidan DUFFY
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Publication number: 20210370336Abstract: A method for aerosolising a liquid comprises the steps of: providing an aperture plate having at least 100 outlet holes per mm2; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 to15 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.Type: ApplicationFiled: February 19, 2021Publication date: December 2, 2021Applicant: Stamford Devices LimitedInventors: Ronan MACLOUGHLIN, Conor Paul Duffy, Brendan HOGAN, Patrick Martin Kelly
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Publication number: 20210283345Abstract: An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes. A controller couples to the aerosol generator, the pump, and the breath sensor. In operation, the controller receives the signal from the breath sensor, controls a flow of fluid to the aerosol generator in response to the signal, and controls the aerosol generator to start aerosolizing the fluid before the patient inhales.Type: ApplicationFiled: May 28, 2021Publication date: September 16, 2021Inventors: Shaun Porter, Louise Sweeney, Ronan MacLoughlin, Jim Fink, Aidan Duffy, Claire Lillis, Conor Duffy, Fran Keating
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Publication number: 20210178088Abstract: Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range.Type: ApplicationFiled: December 3, 2020Publication date: June 17, 2021Inventors: Jim Fink, Lisa Molloy, Ronan MacLoughlin, Claire Elizabeth Lillis, Michael Joseph Casey, John Matthew Mullins, Kieran James Hyland, Joseph Martin Grehan, Niall Scott Smith
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Patent number: 11027077Abstract: An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes. A controller couples to the aerosol generator, the pump, and the breath sensor. In operation, the controller receives the signal from the breath sensor, controls a flow of fluid to the aerosol generator in response to the signal, and controls the aerosol generator to start aerosolizing the fluid before the patient inhales.Type: GrantFiled: March 22, 2018Date of Patent: June 8, 2021Assignee: Stamford Devices Ltd.Inventors: Shaun Porter, Louise Sweeney, Ronan MacLoughlin, Jim Fink, Aidan Duffy, Claire Lillis, Conor Duffy, Fran Keating
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Patent number: 10987474Abstract: An aerosol delivery system that includes an aerosol generator that aerosolizes a fluid for delivery to a patient as a patient inhales. The aerosol delivery system includes a pump coupled to the aerosol generator that pumps the fluid to the aerosol generator, and a breath sensor that emits a signal as the patient breathes. A controller couples to the aerosol generator, the pump, and the breath sensor. In operation, the controller receives the signal from the breath sensor, controls a flow of fluid to the aerosol generator in response to the signal, and controls the aerosol generator to start aerosolizing the fluid before the patient inhales.Type: GrantFiled: March 22, 2018Date of Patent: April 27, 2021Assignee: Stamford Devices Ltd.Inventors: Shaun Porter, Louise Sweeney, Ronan MacLoughlin, Jim Fink, Aidan Duffy, Claire Lillis, Conor Duffy, Fran Keating
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Patent number: 10857313Abstract: Embodiments provide aerosolization device for providing aerosolized medicament to user. The aerosolization device includes conduit, aerosol generator, fluid receiving chamber, restrictor within the conduit, and indicator mechanism. Conduit has an inner wall and a mouthpiece end for causing an inspiratory flow. Aerosol generator includes a vibratable mesh laterally offset from the inner wall. Fluid receiving chamber receives liquid medicament. At least a portion of chamber is tapered such that liquid medicament is directed onto vibratable mesh for aerosolization. Restrictor defines a plurality of apertures that provide increases in pressure differential that vary with inspiratory flow rate within conduit and provide relatively laminar flow downstream of restrictor. Indicator mechanism indicates a state of flow parameters relative to a predefined range. Aerosol generator is configured to aerosolize at least a portion of liquid medicament only when flow parameters of the inspiratory flow are within range.Type: GrantFiled: June 18, 2015Date of Patent: December 8, 2020Assignee: Aerami Therapeutics, Inc.Inventors: Jim Fink, Lisa Molloy, Ronan MacLoughlin, Claire Elizabeth Lillis, Michael Joseph Casey, John Matthew Mullins, Kieran James Hyland, Joseph Martin Grehan, Niall Scott Smith
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Publication number: 20200155788Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.Type: ApplicationFiled: January 23, 2020Publication date: May 21, 2020Applicant: Stamford Devices LimitedInventors: Ronan MACLOUGHLIN, Niall Smith
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Publication number: 20200114112Abstract: A gas therapy system (1) has a flow line (3, 2), a coupler (6) to a gas source, and an aerosol generator (4) for aerosol delivery, and a patient interface such as a nasal interface (2). A controller (10) is configured to modulate gas flow and aerosol delivery in real time. The controller changes gas flow rate and dynamically reduces aerosol delivery during upper gas flow rates such as 60 LPM, and activates aerosol delivery during lower gas flow rates of for example 10 LPM. The control may also include sensors to detect breathing, so that there is a bias towards increased aerosol delivery during inhalation in addition to during lower level gas flow.Type: ApplicationFiled: July 3, 2018Publication date: April 16, 2020Applicant: STAMFORD DEVICES LIMITEDInventors: Ronan MACLOUGHLIN, Shaun PORTER, Conor DUFFY, John POWER
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Patent number: 10617840Abstract: A high flow nasal therapy system (1) has a gas supply (2), a nebulizer (12), and a nasal interface (7). There are two branches (11, 10) and a valve (6) linked with the controller, the branches including a first branch (11) for delivery of aerosol and a second branch (10) for delivery of non-aerosolized gas. The controller controls delivery into the branches (11, 10), in which flow is unidirectional in the first and second branches, from the gas supply towards the nasal interface. The first branch (11) includes the nebulizer (12) and a line configured to store a bolus of aerosol during flow through the second branch (10). The valve (6) comprises a Y-junction between the gas inlet on one side and the branches on the other side.Type: GrantFiled: April 10, 2015Date of Patent: April 14, 2020Assignee: STAMFORD DEVICES LIMITEDInventors: Ronan MacLoughlin, Niall Smith
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Patent number: 10518288Abstract: A method for aerosolising a liquid comprises the steps of: —providing an aperture plate having at least 100 outlet holes per mm2; delivering liquid to the aperture plate; and vibrating the aperture plate to produce an aerosol. The viscosity of the liquid is in the range of from 1 to 15 cP and the surface tension of the liquid is in the range of from 72 to 0.5 mN/m. The output rate of the generated aerosol is greater than 0.01 mL/min.Type: GrantFiled: June 10, 2016Date of Patent: December 31, 2019Assignee: STAMFORD DEVICES LIMITEDInventors: Ronan MacLoughlin, Conor Duffy, Brendan Hogan, Patrick Martin Kelly