Abstract: A data transmission method and apparatus are described. The method includes a receive end receiving a first parameter, where the first parameter includes a parameter of a probability distribution of a hidden variable. The hidden variable is obtained by encoding first data by using an encoder of a variational auto-encoder. The receive end determines the probability distribution based on the first parameter, and samples the probability distribution M times to obtain M pieces of sampled data, where M is a positive integer. The receive end reconstructs the first data based on the M pieces of sampled data. According to the described data transmission method and apparatus, the first parameter is transmitted, so that the receive end can support a plurality of times of sampling, thereby reducing an amount of data transmitted over an air interface, and reducing data transmission overhead.

Abstract: Provided are a B7H4-targeting antibody or a variant thereof, and a bispecific antibody containing the B7H4-targeting antibody, wherein the B7H4-targeting antibody comprises a light chain variable region and a heavy chain variable region. The variant has an amino acid mutation in the light chain variable region or heavy chain variable region of the antibody and can maintain the function of the antibody. The B7H4-targeting antibody has the activity of binding to human B7H4 and cynomolgus macaque B7H4, and does not cross-react with other B7 family members. The B7H4-targeting antibody exhibits good anti-tumor activity, T-cell activation activity and internalization activity in in-vivo and in-vitro experiments, and is more suitable for use as an ADC drug. Further provided is a bispecific antibody targeting B7H4 and CD3, which has a longer half-life, retains good stability and hydrophilicity, and reduces toxicity while ensuring efficacy.

Abstract: The present invention relates to novel antibodies or antigen-binding fragments thereof that specifically bind to CD73 and compositions comprising the antibodies or antigen-binding fragments thereof. The present invention also relates to a nucleic acid encoding the antibody or antigen-binding fragment thereof of the present invention, a vector comprising the polynucleotide, a host cell comprising the nucleic acid or the vector, an immunoconjugate and pharmaceutical composition comprising the antibody or antigen-binding fragment thereof. Furthermore, the present invention relates to the uses of these antibodies or antigen-binding fragments thereof in the immunotherapy, prevention and/or diagnosis of diseases.

Abstract: A semiconductor chip includes an active device and a passive device formed over a substrate. A passivation layer covers the active device and the passive device. A barrier structure surrounds the active device. A ceiling layer is formed across the barrier structure over the active device. The ceiling layer has an opening exposing the barrier structure.

Abstract: A mobile manipulation control method of a quadruped robot with an operation arm, including: obtaining current pose information of the legged mobile manipulator; decomposing a task into subtasks, and prioritizing the subtasks; based on the pose information and a dynamic model, generating a motion trajectory under each subtask; based on the dynamic model, optimizing an optimal plantar force of a supporting leg and an end-of-arm force under each subtask; based on a multi-task spatial projection method, calculating desired control quantity of all joints under different subtasks; and (d) optimizing the optimal plantar force and the desired control quantity with the whole-body dynamic model as a constraint to obtain control torques; and based on the control torques, controlling the legged mobile manipulator's motion. A control system is further provided.

Abstract: An array substrate, a display device, and a fabricating method are disclosed. The array substrate includes a substrate and a thin film transistor disposed on the substrate. The thin film transistor includes a semiconductor layer, and further includes a light-shielding and heat-insulating layer, where the semiconductor layer is disposed above the light-shielding and heat-insulating layer. The light-shielding and heat-insulating layer includes a light-shielding matrix and a flake-shaped cluster structure. The light-shielding matrix includes a porous structure, the porous structure including multiple holes, and the flake-shaped cluster structure is disposed in these holes. The light-shielding and heat-insulating layer is used to shield incident light, and the flake-shaped cluster structure is used to absorb heat generated by the incident light.

Abstract: The present disclosure discloses a method, which includes: obtaining, by controlling to move an electron beam to scan a sample, a diffraction intensity of the sample at each scanning position; initializing a sample transmission function and an electron beam function, establishing, based on the diffraction intensity, the sample transmission function, and the electron beam function, a forward propagation model containing to-be-optimized parameters, and calculating a value of a loss function; solving a derivative of the loss function with respect to the to-be-optimized parameters, to obtain gradients of the to-be-optimized parameters in the sample transmission function and the electron beam function, optimizing the to-be-optimized parameters based on the gradients, and updating the value of the loss function; and repeating an iteration process until an iteration termination condition is satisfied, and outputting an optimized sample transmission function and an optimized electron beam function.

Abstract: A method for fabricating a package structure is provided. The method includes premixing cellulose nanofibrils (CNFs) and a two-dimensional (2D) material in a solvent to form a solution; removing the solvent from the solution to form a composite filler; mixing a prepolymeric material with the composite filler to form a composite material; and performing a molding process using the composite material.

Abstract: A method for determining an auxiliary bit of a polar code and an apparatus. At least K sub-channels are determined based on reliability of a first sub-channel set, where the K sub-channels carry information bits. S sub-channel subsets are determined based on the first sub-channel set, an ith sub-channel subset in the S sub-channel subsets includes Ji sub-channels carrying auxiliary bits and Ki sub-channels in the K sub-channels. Sequence numbers of the Ji sub-channels carrying the auxiliary bits are after sequence numbers of the Ki sub-channels. The auxiliary bits are known redundancy check RC bits. Polar encoding is performed on the information bits and the auxiliary bits, to output polar-encoded data.

Abstract: Determining a class-specific predictor indicator importance can include generating, using machine learning, a prediction model having a tree structure including nodes, class label subgroups, and class-specific predictor indicators. A class-specific predictor indicator importance can be generated for a selected class-specific predictor indicator by merging a term predictor indicator frequency and a purity predictor indicator frequency at each instance of the selected class-specific predictor indicator within one or more nodes of the tree structure. A representation of the tree structure displayed in a graphical user interface can depict each path between a root node of the tree structure and a leaf node mapped to the selected class label subgroup having a node containing an instance of the selected class-specific predictor indicator in a manner that contrasts with other paths between the root node and other leaf nodes of the tree structure.

Abstract: In an embodiment, a system includes: a tool port of a semiconductor processing tool; a processing port with an internal processing port location and an external processing port location; a robot configured to move a die vessel between the internal processing port location and the tool port; and an actuator configured to move the die vessel between the internal processing port location and the external processing port location.

Abstract: A nanosized complex includes siRNA and a compound comprising formula (I):

Abstract: A modified electrode, manufacturing method thereof and use thereof are provided. The manufacturing method includes steps of: mixing a carbon nanomaterial with 2,2?-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid), followed by drop-casting on a screen-printed carbon electrode, to obtain carbon material modified electrodes; and electrochemically pre-treating the carbon material modified electrodes by cyclic voltammetry technique, constant potential technique, or constant current technique to obtain a modified electrode. 3-Ethyl-6-sulfonate benzothiazolinone imine and 3-ethyl-6-sulfonate benzothiazolone compound are formed on a surface of the modified electrode, and the modified electrode is used for protein analysis, protein immobilization and related biosensor, electrochemical catalysis or biofuel cells.

Abstract: A display device, a display panel, and an array substrate are provided. The array substrate includes an active layer and a light-blocking and heat-insulating layer. The light-blocking and heat-insulating layer is arranged on a side of the active layer and configured to block light and insulate heat for the active layer. The light-blocking and heat-insulating layer includes light-absorbing materials and light-reflecting materials. One of the light-absorbing materials and the light-reflecting materials form a light-blocking body. The other one of the light-absorbing materials and the light-reflecting materials are dispersed in the light-blocking body.

Abstract: Fragmentation of cell-free DNA molecules is measured and used for various purposes, including determining methylation, e.g., at a particular site of a DNA molecule, at a particular genomic site in a reference genome for a biological sample (e.g., plasma, serum, urine, saliva) of cell-free DNA of a subject, or for a particular region in the reference genome for the biological sample (also just referred to as a sample). Various types of fragmentation measurements can be used, e.g., end motifs and cleavage profiles. Another purpose is determining a fractional concentration of DNA of a particular tissue type (e.g., clinically-relevant DNA). Another purpose is determining a pathology of a subject using a biological sample including cell-free DNA. The cell-free DNA can be of the subject or of a pathogen (e.g., a virus) in the subject's sample. Sites/regions that are hypermethylated, hypomethylated, 5hmC-enriched, and 5hmC-depleted for a particular tissue type can be used.

Abstract: A key generation method and an apparatus are provided. One example key generation method includes the following steps: determining, by a communication apparatus, that a master base station or a secondary base station serves as an integrated access and backhaul (IAB) donor, wherein the master base station and the secondary base station are connected to an IAB node; and performing at least one of the following when the master base station serves as the IAB donor, generating, by the communication apparatus, an IAB key KIAB based on a master base station key; or when the secondary base station serves as the IAB donor, generating, by the communication apparatus, the IAB key KIAB based on a secondary base station key.

Abstract: Transaction modification based on modeled profiles is described. In an example, transaction data can be received by a payment processing system. The payment processing system can generate, using a trained model, profiles. Based at least in part on (i) receiving an indication that a buyer and a merchant are engaged in, or likely to be engaged in, a transaction and (ii) determining that a characteristic of the transaction corresponds to a profile, generating a communication to enable the buyer or the merchant to modify the transaction in association with processing of the transaction.

Abstract: The present invention relates to a maca extract and uses thereof. The part of the maca extract extracted with polar solvent has anti-thrombotic activity, the part of the maca extract extracted with medium and low polarity solvents has anti-neutrophilic inflammatory and anti-allergic activities, the part of the maca extract extracted with low polarity solvent has anti-neutrophilic inflammatory activity and has pro-angiogenic activity.

Abstract: This application provides a method for processing a round trip delay, a related apparatus, and a readable storage medium, and pertains to the field of communications technologies. The method includes: receiving a delay quantization parameter of a common round trip delay (RTD), where the delay quantization parameter includes a first quantization parameter, and the first quantization parameter is used to indicate a height-related delay; and obtaining the common RTD based on the delay quantization parameter. The height-related delay is indicated by using the first quantization parameter, so that the common RTD is obtained based on the first quantization parameter.

Abstract: The present invention relates to a method of treating autoimmune/autoinflammatory diseases and hematological malignancies in a subject.