Patents by Inventor Rong-Gui Hu

Rong-Gui Hu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modulation of nitric oxide signaling through signaling through specific regulation by arginylation and the N-end rule pathway
    Patent number: 7575881
    Abstract: Screening assays that allow for the identification of agents that modulate the activity of the arginylation branch of the N-end rule pathway are provided. Also provided are method of using an agent that modulate the activity of the arginylation branch of the N-end rule pathway to increase or decrease protein degradation in a cell, and to modulate physiologic and pathologic associated with N-end rule pathway mediated arginylation.
    Type: Grant
    Filed: September 16, 2005
    Date of Patent: August 18, 2009
    Assignee: California Institute of Technology
    Inventors: Rong-Gui Hu, Jun Sheng, Yong Tae Kwon, Anna Kashina, Alexander Varshavsky
  • Modulation of nitric oxide signaling through signaling through specific regulation by arginylation and the N-end rule pathway
    Publication number: 20060084097
    Abstract: Screening assays that allow for the identification of agents that modulate the activity of the arginylation branch of the N-end rule pathway are provided. Also provided are method of using an agent that modulate the activity of the arginylation branch of the N-end rule pathway to increase or decrease protein degradation in a cell, and to modulate physiologic and pathologic associated with N-end rule pathway mediated arginylation.
    Type: Application
    Filed: September 16, 2005
    Publication date: April 20, 2006
    Applicant: CALIFORNIA INSTITUTE OF TECHNOLOGY
    Inventors: Rong-Gui Hu, Jun Sheng, Yong Kwon, Anna Kashina, Alexander Varshavsky
  • Modulation of angiogenesis through targeting of cysteine oxygenase activity
    Publication number: 20040023311
    Abstract: The invention provides methods and compositions for modulating angiogenesis in a subject. The methods of modulating angiogenesis in a subject include administering to the subject a modulator of N-terminal cysteine oxygenase activity. The invention also provides a method of identifying such a modulator and a method of in vitro screening for modulators of N-terminal cysteine oxygenase activity. Additionally, the invention provides a method of treating an angiogenesis-related disorder.
    Type: Application
    Filed: March 21, 2003
    Publication date: February 5, 2004
    Inventors: Yong Tae Kwon, Ilia V. Davydov, Rong-gui Hu, Fangyong Du, Alexander Varshavsky