Abstract: Various methods and systems are provided for ultrasound imaging. In one embodiment, a method comprises acquiring, with an ultrasound transducer of a scanning apparatus during an ultrasound scan of a patient, an ultrasound image, detecting, with an artificial intelligence model, a region of interest within the ultrasound image including a possible tumor, acquiring, with the ultrasound transducer, an elastic image of tissue within the region of interest, and displaying, with a display device, the elastic image. In this way, shear wave elastography may be automatically targeted to a region of interest, thereby reducing the processing load for the analysis and enabling a higher elasticity imaging frame rate for three-dimensional ultrasound imaging.

Abstract: A nanosized complex includes siRNA and a compound comprising formula (I):

Abstract: A compound comprising formula (I): wherein R1 is an akylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted akyl group, an akenyl group, an acyl group, an aromatic group, polymer, a targeting group, or a detectable moiety; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.

Abstract: A PET/SPECT probe includes the following formula: P—1,—C wherein P is a EDB-FN targeting peptide, C is a PET/SPECT contrast agent; and L is an optional linker that covalently links the peptide to the contrast agent.

Abstract: Apparatus, systems and methods for irrigating lands are disclosed. In one example, an irrigation system is disclosed. The irrigation system includes a gate and a microcontroller unit (MCU). The gate is configured for adjusting a water flow for irrigating a piece of land. The MCU is configured for controlling the gate to adjust the water flow based on environmental information related to the piece of land.

Abstract: A compound comprising formula (I): wherein R1 is an akylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted akyl group, an akenyl group, an acyl group, an aromatic group, polymer, a targeting group, or a detectable moiety; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.

Abstract: Various methods and systems are provided for ultrasound imaging. In one embodiment, a method comprises acquiring, with an ultrasound transducer of a scanning apparatus during an ultrasound scan of a patient, an ultrasound image, detecting, with an artificial intelligence model, a region of interest within the ultrasound image including a possible tumor, acquiring, with the ultrasound transducer, an elastic image of tissue within the region of interest, and displaying, with a display device, the elastic image. In this way, shear wave elastography may be automatically targeted to a region of interest, thereby reducing the processing load for the analysis and enabling a higher elasticity imaging frame rate for three-dimensional ultrasound imaging.

Abstract: A molecular probe includes the following formula: P-L-C wherein P is a EDB-FN targeting peptide, C is a contrast agent; and L is a non-peptide linker that covalently links the peptide to the contrast agent.

Abstract: A composition includes a polysaccharide at least one retinoid linked to at least one monosaccharide subunit of the polysaccharide with a covalent linkage. The linkage being degradable by hydrolysis during digestion of the composition to provide controlled, delayed, and/or sustained delivery of the at least one retinoid upon enteral administration of the composition to a subject.

Abstract: Apparatus, systems and methods for irrigating lands are disclosed. In one example, an irrigation system is disclosed. The irrigation system includes a gate and a microcontroller unit (MCU). The gate is configured for adjusting a water flow for irrigating a piece of land. The MCU is configured for controlling the gate to adjust the water flow based on environmental information related to the piece of land.

Abstract: The present disclosure discloses the wireless virtual mouse. The wireless virtual mouse comprises a head-mounted device and a wireless virtual mouse body. The wireless virtual mouse body comprises a head motion detection module, an eyelid blinking detection module, a communication module, and a power supply module. The head motion detection module collects relative changes of head position through an aerial attitude sensor. A wireless transceiver of the communication module sends signals generated based upon the relative changes of the head position to a computer, and a cursor on a screen of the computer changes synchronously based upon the signals. The eyelid blinking detection module collects a movement distance and a movement duration of an eyelid through a photoelectric motion sensor, and the wireless transceiver sends change signals generated based upon the movement distance and the movement duration to the computer.

Abstract: A plasticizer, which is biodegradable, has a molecule including a central structure, at least two connecting structures and at least one side-chain structure. The central structure includes at least one of a benzene derivative and at least one amino acid. The connecting structures are respectively connected to the central structure, wherein the connecting structures include a first connecting structure and a second connecting structure. The first connecting structure is an amine group, and the second connecting structure is a carboxyl group. The side-chain structure is a chain of multiple carbon atoms, and the side-chain structure is connected to at least one of the first connecting structure and the second connecting structure. An amide bond is formed as the side-chain structure connected to the amine group, and an ester bond is formed as the side-chain structure connected to the carboxyl group.

Abstract: A molecular probe includes the following formula: P-L-C wherein P is a EDB-FN targeting peptide, C is a contrast agent; and L is a non-peptide linker that covalently links the peptide to the contrast agent.

Abstract: A nanosized complex includes a nucleic acid and a compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or a polymer, a targeting group, a detectable moiety, or a linker, or a combination thereof, and at least one of R4 and R5 includes a retinoid or retinoid derivative that targets and/or binds to an interphotoreceptor retinoid binding protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.

Abstract: A compound comprising formula (I): wherein R1 is an alkylamino group or a group containing at least one aromatic group; R2 and R3 are independently an aliphatic group or hydrophobic group; R4 and R5 are independently H, a substituted or unsubstituted alkyl group, an alkenyl group, an acyl group, or an aromatic group, or includes a polymer, a targeting group, or a detectable moiety, and at least one of R4 and R5 includes a targeting group that targets and/or binds to a retinal or visual protein; a, b, c, and d are independently an integer from 1 to 10; and pharmaceutically acceptable salts thereof.

Abstract: The present disclosure discloses the wireless virtual mouse. The wireless virtual mouse comprises a head-mounted device and a wireless virtual mouse body. The wireless virtual mouse body comprises a head motion detection module, an eyelid blinking detection module, a communication module, and a power supply module. The head motion detection module collects relative changes of head position through an aerial attitude sensor. A wireless transceiver of the communication module sends signals generated based upon the relative changes of the head position to a computer, and a cursor on a screen of the computer changes synchronously based upon the signals. The eyelid blinking detection module collects a movement distance and a movement duration of an eyelid through a photoelectric motion sensor, and the wireless transceiver sends change signals generated based upon the movement distance and the movement duration to the computer.

Abstract: A compound includes at least one targeting peptide coupled to a detectable moiety. The targeting peptide binds to EDB-FN or EDA-FN and includes at least one of amino acid sequence selected from the group consisting of SEQ ID NOs: 1-30.

Abstract: A pharmaceutical composition includes a retinylamine derivative having the following formula: where R1 is an amino acid residue, a dipeptide or a tripeptide that is linked to the retinylamine by an amide bond.

Abstract: A nanosized complex includes siRNA and a compound comprising formula (I):