Abstract: Compounds of Formula (I) and (II), or a stereoisomer, tautomer, solvate, prodrug or salt thereof, and methods of use as Janus kinase inhibitors are described herein.

Abstract: The invention relates to the field of pesticide technology, and in particular a type of carboxylic acid derivative-substituted iminoaryl compound, preparation method, herbicidal composition and use thereof. The compound, as shown in general formula I: wherein, Q represents Y represents halogen, haloalkyl or cyano; Z represents halogen; M represents CH or N; W represents OX5, SX5 or N(X5)2; X represents —CX1X2-(alkyl)n-, -alkyl-CX1X2-(alkyl)n- or —(CH2)r—; X3 and X4 each independently represent O, S, NH or N-alkyl, etc. The compound has excellent herbicidal activity against gramineous weeds, broadleaf weeds, cyperaceae weeds and so on even at low application rates, and has high selectivity for crops.

Abstract: The invention belongs to the technical field of pesticides, and specifically relates to a 4-pyridinyl formamide compound or a derivative thereof, a preparation method therefor, a herbicidal composition and the use thereof. The 4-pyridinyl formamide compound is as represented by formula (I), wherein, X and Y each independently represent nitro, halogen, cyano, formyl, thiocyano, mercapto, etc.; and M represents an unsubstituted or substituted structure (II). The compound, and the derivative and the composition thereof have excellent herbicidal activity and a higher crop safety, and establish good selectivity, especially for key crops such as wheat and rice.

Abstract: The invention relates to the field of pesticide technology, and in particular a type of fused-ring substituted aromatic compound, preparation method, herbicidal composition and use thereof. The fused-ring substituted aromatic compound, represented by general formula I: wherein, Q represents etc.; Y represents halogen, haloalkyl, cyano, nitro or amino; Z represents H, halogen or hydroxy; M represents CH or N; Het represents a cyclic structure that shares two carbon atoms at 4- and 5-positions with isoxazoline ring to form a fused ring; X1, X2 each independently represent H, halogen or nitro etc. The compound has excellent herbicidal activity against gramineous weeds, broadleaf weeds, etc. even at low application rates, and has high selectivity for crops.

Abstract: The invention relates to the field of pesticide technology, and in particular a type of substituted 1,2,4-triazolo[4,3-a]pyridine derivatives, preparation method, herbicidal composition and use thereof. A substituted 1,2,4-triazolo[4,3-a]pyridine derivative, as shown in Formula I: wherein, Q represents X and Z each independently represent hydrogen, halogen, cyano or nitro, etc.; Y represents hydrogen, halogen, formyl, cyanoalkyl; or an alkyl, alkenyl or alkynyl, each of which contains or does not contain a halogen, etc. The compound and its composition have excellent herbicidal activity and higher crop safety, especially good selectivity for key crops such as rice.

Abstract: The present invention belongs to the technical field of pesticides, and specifically relates to an isoxazoline oxime formate compound, a preparation method therefor, and a herbicidal composition and a use thereof. The isoxazoline oxime formate compound is shown in general formula I. Wherein, Y represents halogen, haloalkyl, cyano, nitro or amino; Z represents hydrogen, halogen or hydroxyl; Q represents M represents CH or N; X1, X2 and X3 each independently represent hydrogen, etc.; X4 and X5 each independently represent hydrogen, halogen, cyano or nitro, etc. The compound also has an excellent herbicidal activity against grassy weeds, broadleaf weeds, etc. at a low application rate, and has a high selectivity to crops.

Abstract: The invention belongs to the technical field of pesticides, and specifically relates to a type of substituted-isoxazoline-containing aromatic compound, preparation method therefor, herbicidal composition and use thereof. The compound is as shown in general formula I: Wherein, Q represents Y represents halogen, halogenated alkyl or cyano; Z represents halogen; X1, X2 each independently represent hydrogen, halogen, alkyl, etc.; X3 represents halogen, cyano, etc.; X4 each independently represents —COOR5 or -alkyl-COOR5; R5 each independently represents hydrogen, alkyl, etc.. The compound has excellent herbicidal activity against gramineous weeds, broadleaf weeds, and so on even at low application rates, and has high selectivity for crops.

Abstract: The invention belongs to the technical field of agricultural chemicals, and particularly relates to an N-(1,3,4-oxadiazol-2-yl)arylcarboxamide compound or a salt thereof, a preparation method, a herbicidal composition and a use thereof. The compound is as shown in the following Formula I: wherein X represents O, S, SO, SO2 or NR1; Y represents halogen, cyano, cyanoalkyl, carboxyl, nitro, etc.; or —X—Y represents unsubstituted or substituted five- or six-membered heterocyclyl or heteroaryl; Z represents hydrogen, halogen, cyano, OR4, -alkyl-OR4, —O-alkyl-N(R5)2, etc., M represents hydrogen, OR6, SR6, COR6, COOR6, CON(R7)2, etc. The compound has advantages of a low dosage for use, excellent herbicidal activity, and higher crop safety, especially good selectivity for key crops such as rice.

Abstract: A substituted thiazole aromatic ring compound and a preparation method therefor, a herbicidal composition and use thereof. The substituted thiazole aromatic ring compound is as shown in general formula I: Wherein, Y represents halogen, halogenated alkyl, cyano, nitro or amino; Q represents M represents CH or N; X represents X1 represents O or S; X2 represents OX3, SX3 or N(X3)2. The compound has excellent herbicidal activity against gramineous weeds, broadleaf weeds, and so on even at low application rates, and has high selectivity for crops.

Abstract: The present invention belongs to the technical field of pesticides, and in particular relates to a pyridazinol compound, a derivative thereof, a preparation method therefor, a herbicidal composition and the use thereof. The pyridazinol compound is as represented by general formula I, wherein X represents and the ring is an unsubstituted or substituted aryl or unsubstituted or substituted heterocyclyl containing a carbon atom at the 1-position; Y represents haloalkyl; and Z represents halogen, cyano, hydroxy, etc. The derivative refers to an agriculturally acceptable derivative of the hydroxyl group at the 4-position of the pyridazine ring in the general formula I, including a salt, an ester, an oxime, a hydroxylamine and an ether derivative, etc. The compound, the derivative thereof and the composition thereof have good herbicidal activity and crop safety.

Abstract: The invention belongs to the technical field of agricultural chemicals, and in particular relates to a pyridazinol compound represented by the Formula I, a derivative, preparation method, herbicidal composition and use thereof.

Abstract: The invention belongs to the technical field of agricultural chemicals, and particularly relates to an aryl formamide compound containing chiral sulfur oxide or salt thereof, a preparation method, a herbicidal composition and a use thereof. The aryl formamide compound containing chiral sulfur oxide or salt thereof has the following structural formula: Z1, and Z2 each independently represent nitro, halogen, or cyano, etc.; X represents unsubstituted or substituted unsubstituted or substituted unsubstituted or substituted unsubstituted or substituted unsubstituted or substituted unsubstituted or substituted or unsubstituted or substituted Q represents halogen, cyano, cyanoalkyl, or nitro, etc.; Y represents hydrogen, etc.; wherein the compound has advantages of excellent herbicidal activity, higher crop safety, and especially good selectivity for key crops such as wheat, rice, corn.

Abstract: The invention relates to the field of pesticide technology, and in particular a type of substituted thiadiazinone dioxide, preparation method, herbicidal composition and application thereof. The substituted thiadiazinone dioxide, as shown in general formula I. wherein, R1 and R2 each independently represent hydrogen, cyano or alkyl with or without halogen and so on; X represents hydrogen or halogen; Y represents C—Z or N; Z represents hydrogen or halogen; and when X represents halogen, Z represents hydrogen. The compound has excellent herbicidal activity against gramineous weeds, broadleaf weeds or amaranthaceous weeds, and has high selectivity for crops such as soybean, corn, rice or wheat.

Abstract: The invention relates to the field of pesticide technology, and in particular to a type of R-pyridyloxycarboxylic acid and salt, ester derivative, preparation method, herbicidal composition and application thereof. The R-pyridyloxycarboxylic acid is represented by formula I, wherein, A, B each independently represent halogen, alkyl or cycloalkyl with or without halogen; C represents hydrogen, halogen, alkyl, haloalkyl; Q represents halogen, cyano, cyanoalkyl and the like; Y represents nitro or NR1R2; the salt is metal salt, amine salt, sulfonium salt, phosphonium salt; the ester is wherein, X represents O or S; M represents alkyl, alkenyl, alkynyl and the like with or without halogen. The compound has excellent herbicidal activity and higher crop safety, especially good selectivity for key crops such as rice.

Abstract: The invention relates to the field of pesticide technology, and in particular a type of pyridyloxy thioester derivative, preparation method, herbicidal composition and application thereof. The pyridyloxy thioester derivative is represented by formula I, wherein, A, B each independently represent halogen, or alkyl or cycloalkyl with or without halogen; C represents hydrogen, halogen, alkyl or haloalkyl; Q represents halogen, cyano, cyanoalkyl, hydroxyalkyl, amino, nitro, formyl, alkyl with or without halogen or the like; M represents alkyl or alkenyl with or without halogen or the like; X represents nitro or NR1R2. The compound has excellent herbicidal activity and higher crop safety, especially good selectivity for key crops such as rice.

Abstract: The invention relates to the field of pesticide technology, and in particular a type of pyridyloxy carboxylate derivative, preparation method, herbicidal composition and application thereof. The pyridyloxy carboxylate derivative is represented by formula I, wherein, A, B each independently represent halogen, or alkyl or cycloalkyl with or without halogen; C represents hydrogen, halogen, alkyl or haloalkyl; Q represents halogen, cyano, cyanoalkyl, hydroxyalkyl, amino, nitro, formyl, alkyl with or without halogen or the like; M represents -alkyl-R, R represents unsubstituted or substituted heterocyclyl, aryl or heteroaryl; Y represents O or S; X represents nitro or NR1R2. The compound has excellent herbicidal activity and higher crop safety, especially good selectivity for key crops such as rice and soybean.

Abstract: The invention relates to the field of pesticide technology, and in particular a type of pyridyloxy carboxylic oxime derivative, preparation method, herbicidal composition and application thereof. The pyridyloxy carboxylic oxime derivative is represented by formula I, wherein, A, B each independently represent halogen, or alkyl or cycloalkyl with or without halogen; C represents hydrogen, halogen, alkyl or haloalkyl; Q represents halogen, cyano, cyanoalkyl, hydroxyalkyl, amino, nitro, formyl, alkyl with or without halogen and the like; R1 and R2 independently represent hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkenyl, cycloalkyl, alkoxy, acyloxy, alkylthio, or unsubstituted or substituted aryl, etc.; M represents nitro or NR3R4. The compound has excellent herbicidal activity and higher crop safety, especially good selectivity for key crops such as rice.

Abstract: The invention relates to the field of pesticide technology, and in particular a type of pyridyloxy carboxylate derivative, preparation method, herbicidal composition and application thereof. The pyridyloxy carboxylate derivative is represented by formula I, wherein, A, B each independently represent halogen, or alkyl or cycloalkyl with or without halogen; C represents hydrogen, halogen, alkyl or haloalkyl; Q represents halogen, cyano, cyanoalkyl, hydroxyalkyl, amino, nitro, formyl, alkyl or alkenyl with or without halogen or the like; M represents -alkyl-R, -haloalkyl-R or X represents nitro or NR1R2. The compound has excellent herbicidal activity and higher crop safety, especially good selectivity for key crops such as rice and soybean.

Abstract: The invention belongs to the technical field of agricultural chemicals, and in particular relates to a five-membered ring-substituted pyridazinol compound and a derivatives thereof, preparation method, herbicidal composition and application thereof. The compound is as shown in Formula I: wherein, X is halogen, cyano, alkyl, halogenated alkyl, alkoxy, halogenated alkoxy, R1R2N—(C?O)—, or R1R2N—, etc.; Ar is Het is a 5-membered unsaturated ring, the ring contains, besides the 1-C atom, 0 to 4 atoms or radicals follows to form the ring: O, NRb, S; Ra is one or more groups selected from: hydrogen, halogen, R—O—(CH2)n—, and R1R2R3SiO—, etc.; m is 0 or 1, n and q are independently an integer from 0 to 8, p is an integer from 1 to 8; R is hydrogen, or a halogen-containing or not containing group selected from alkyl, and alkenyl, etc.; Rb, R1, R2, R3 are each independently hydrogen, nitro, hydroxy, or amino, etc.

Abstract: The invention belongs to the technical field of agricultural chemicals, and in particular relates to a pyridine ring-substituted pyridazinol compound and a derivatives thereof, preparation method, herbicidal composition and application thereof. The compound is as shown in Formula I: wherein, X is halogen, cyano, alkyl, halogenated alkyl, alkoxy, halogenated alkoxy, R1R2N—(C?O)—, R1R2N—, hydroxy, or unsubstituted or substituted aryl; Y is independently selected from hydrogen, halogen, cyano, nitro, R—O—(CH2)n—, and R1R2 R3SiO—, etc.; r is an integer from 0 to 4, m is 0 or 1, n and q are independently an integer from 0 to 8, p is an integer from 1 to 8; R is hydrogen, or a halogen-containing or not containing group selected from alkyl, alkenyl, alkynyl, and cycloalkyl, etc.; R1, R2, R3 are each independently hydrogen, nitro, or hydroxy, etc. The compound and the derivative, as well as the composition thereof have very high herbicidal activity and good selectivity, and are safe for crops.