Patents by Inventor Rongjun He

Rongjun He has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Small molecule inhibitors of protein tyrosine phosphatases and uses thereof
    Patent number: 10532977
    Abstract: Small molecule compounds derived from ?-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB, LMWPTP, and Laforin. Use of these compounds as pharmaceutical agents for treating diseases associated with abnormal protein tyrosine phosphatase activity is also provided.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: January 14, 2020
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Zhong-Yin Zhang, Rongjun He
  • Protein tyrosine phosphatases or SHP2 inhibitors and uses thereof
    Patent number: 10494332
    Abstract: Small molecule compounds derived from ?-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB, LMWPTP, and Laforin. Use of these compounds as pharmaceutical agents for treating diseases associated with abnormal protein tyrosine phosphatase activity is also provided.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: December 3, 2019
    Assignee: Indiana University Research and Technology Corporation
    Inventors: Zhong-Yin Zhang, Rongjun He
  • SMALL MOLECULE INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES AND USED THEREOF
    Publication number: 20180170861
    Abstract: Small molecule compounds derived from ?-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB, LMWPTP, and Laforin. Use of these compounds as pharmaceutical agents for treating diseases associated with abnormal protein tyrosine phosphatase activity is also provided.
    Type: Application
    Filed: June 1, 2016
    Publication date: June 21, 2018
    Inventors: Zhong-Yin Zhang, Rongjun He
  • PROTEIN TYROSINE PHOSPHATASES OR SHP2 INHIBITORS AND USES THEREOF
    Publication number: 20180170862
    Abstract: Small molecule compounds derived from ?-sulfophenylacetic amide (SPAA) are provided as novel sulfonic acid based pTyr mimetics. These compounds effectively inhibit a variety of protein tyrosine phosphatases (PTPs), such as mPTPA, mPTPB, LMWPTP, and Laforin. Use of these compounds as pharmaceutical agents for treating diseases associated with abnormal protein tyrosine phosphatase activity is also provided.
    Type: Application
    Filed: June 1, 2016
    Publication date: June 21, 2018
    Inventors: Zhong-Yin Zhang, Rongjun He
  • Intelligent waterless printing and dyeing control equipment and control method thereof
    Patent number: 8287063
    Abstract: The invention relates to an intelligent waterless printing and dyeing control equipment and a control method thereof. The equipment comprise of: a control apparatus consisting of a programmable logic controller and a superior monitor computer and a robot, wherein, the programmable logic controller communicates with the superior monitor computer via MPI bus, receiving control signal coming from an operating panel and the robot via digitals input module for transmitting the control command to the robot, connecting with the dye conveyer apparatus and the printing and dyeing apparatus via the digitals output module; the superior monitor computer communicates with the servo controllers via CAN bus.
    Type: Grant
    Filed: September 12, 2007
    Date of Patent: October 16, 2012
    Assignees: Dandong Unik Textile., Ltd, Liaoning Fixed Star Chemicals (Group) Co., Ltd
    Inventors: Xinning Yan, Rongjun He
  • INTELLIGENT WATERLESS PRINTING AND DYEING CONTROL EQUIPMENT AND CONTROL METHOD THEREOF
    Publication number: 20090237431
    Abstract: The invention relates to an intelligent waterless printing and dyeing control equipment and a control method thereof. The equipment comprise of: a control apparatus consisting of a programmable logic controller and a superior monitor computer and a robot, wherein, the programmable logic controller communicates with the superior monitor computer via MPI bus, receiving control signal coming from an operating panel and the robot via digitals input module for transmitting the control command to the robot, connecting with the dye conveyer apparatus and the printing and dyeing apparatus via the digitals output module; the superior monitor computer communicates with the servo controllers via CAN bus.
    Type: Application
    Filed: September 12, 2007
    Publication date: September 24, 2009
    Inventors: Xinning Yan, Rongjun He