Patents by Inventor Ronglai Shen

Ronglai Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PERIPHERAL BLOOD PHENOTYPE LINKED TO OUTCOMES AFTER IMMUNOTHERAPY TREATMENT
    Publication number: 20240085417
    Abstract: Provided are methods of assigning a LAG+, LAG?, or PRO immunotype to a cancer patient based on the frequencies of LAG-3+CD8+T-cells, Ki67+CD8+T-cells, Tim-3+CD8+T-cells, and ICOS+CD8+T-cells in a peripheral blood sample from the patient, and selecting an anti-cancer therapy, for example, an immune checkpoint blockade (ICB) therapy, based on the patient's immunotype.
    Type: Application
    Filed: January 20, 2022
    Publication date: March 14, 2024
    Inventors: Margaret K. Callahan, Arshi Arora, Taha Merghoub, Katherine S. Panageas, Michael A. Postow, Ronglai Shen, Jedd D. Wolchok
  • Prognostic meta signatures and uses thereof
    Publication number: 20060292610
    Abstract: The present invention relates the novel statistical analyses of gene expression data. In particular, the present invention provides prognostic meta signatures (e.g. representing cancer samples) that identify genes with altered expression across several studies.
    Type: Application
    Filed: June 6, 2006
    Publication date: December 28, 2006
    Applicant: Regents of the University of Michigan
    Inventors: Ronglai Shen, Debashis Ghosh, Arul Chinnaiyan