Patents by Inventor Rongrong XIE

Rongrong XIE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • FXR SMALL-MOLECULE AGONIST, AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20230357244
    Abstract: A strong FXR small-molecule agonist, and a preparation method therefor and use thereof, the structure of the agonist being represented by formula (I), are provided. In the formula, each substituent is as defined in the description and the claims. The compound provided has the advantages of high FXR agonist activity, simple synthesis, easily available raw materials and the like, and can be used for preparing medicines for treating FXR related diseases.
    Type: Application
    Filed: September 28, 2021
    Publication date: November 9, 2023
    Inventors: Huaqiang XU, Jia LI, Jingjing SHI, Yi ZANG, Dandan SUN, Mingliang LIU, Rongrong XIE, Erli YOU, Lixin GAO, Qian TAN
  • NKG2A ANTIBODY, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20220259306
    Abstract: Provided are an antibody targeting NKG2A, a preparation method therefor and use thereof. Specifically, provided is a new mouse or humanized monoclonal antibody targeting NKG2A, and a method for preparing the monoclonal antibody. The monoclonal antibody can bind to an NKG2A antigen with high specificity, and has high affinity and significant activities such as anti-tumor activity.
    Type: Application
    Filed: November 6, 2019
    Publication date: August 18, 2022
    Inventors: Qing DUAN, Lile LIU, Dazhi YANG, Jing GAO, Lili HU, Ruirui SUI, Dongxu WANG, Ye HAN, Rongrong XIE, Yan LU, Xiaohui SHAO, Jie ZHANG, Wenming ZHOU, Cuicui GUO, Guozhen TONG, Lina WANG, Chaohui DAI, Mengying WANG
  • FXR SMALL MOLECULE AGONIST AND PREPARATION METHOD THEREFOR AND USE THEREOF
    Publication number: 20220213083
    Abstract: An FXR small molecule agonist and a preparation method therefor and a use thereof, having a structure as shown in formula (I). The compound represented by formula (I) has FXR agonistic activity and is capable of preparing drugs for treatment of FXR-related diseases.
    Type: Application
    Filed: April 20, 2020
    Publication date: July 7, 2022
    Inventors: Huaqiang XU, Jia LI, Jingjing SHI, Yi ZANG, Dandan SUN, Mingliang LIU, Rongrong XIE, Erli YOU, Lixin GAO, Qian TAN
  • CD73 ANTIBODY, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20220098319
    Abstract: An antibody targeting CD73, a preparation method therefor and a use thereof. The provided monoclonal antibody can bind to a CD73 antigen with high specificity, and has high affinity and significant antitumor activity.
    Type: Application
    Filed: January 13, 2020
    Publication date: March 31, 2022
    Inventors: Dongxu WANG, Qing DUAN, Lile LIU, Tatchi Teddy YANG, Hu LIU, Ye HAN, Rongrong XIE, Xiaohui SHAO, Peng WANG, Qin ZHONG, Yajun HUANG, Jian WU, Meiling WANG, Yuandong WANG