Patents by Inventor Rongsheng E. Wang

Rongsheng E. Wang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LINKING AMINO ACID SEQUENCES, MANUFACTURING METHOD THEREOF, AND USE THEREOF
    Publication number: 20230138393
    Abstract: This invention provides compositions comprising linked amino acid sequences, pharmaceutical compositions comprising linked amino acid sequences, and methods of making thereof. This invention also provides methods of delivering said compositions to subjects and methods of treating various disorders and diseases using the said compositions.
    Type: Application
    Filed: February 12, 2021
    Publication date: May 4, 2023
    Inventors: Rongsheng E. Wang, Md Shafiqul Islam, Zhigang Lyu, Yue Zhao, Zakey Yusuf Buuh
  • Switchable antibody conjugate
    Patent number: 11492413
    Abstract: The present invention relates to a Fab fragment based switchable antibody system for generating site-specific antibody conjugates. Methods are described for the attachment of molecules to specific sites the Fab fragment and for the attachment of the Fab fragment to a target molecule (e.g., an antibody) directed against any desired target antigen (tumor, bacterial, fungal, viral, parasitic etc.) The attachment is via binding of the Fab fragment to an epitope linked to the target molecule.
    Type: Grant
    Filed: December 4, 2018
    Date of Patent: November 8, 2022
    Assignee: Temple University—Of The Commonwealth System of Higher Education
    Inventors: Rongsheng E. Wang, Zhigang Lyu, Haley L. Wissler
  • Switchable antibody conjugate
    Publication number: 20190211111
    Abstract: The present invention relates to a Fab fragment based switchable antibody system for generating site-specific antibody conjugates. Methods are described for the attachment of molecules to specific sites the Fab fragment and for the attachment of the Fab fragment to a target molecule (e.g., an antibody) directed against any desired target antigen (tumor, bacterial, fungal, viral, parasitic etc.) The attachment is via binding of the Fab fragment to an epitope linked to the target molecule.
    Type: Application
    Filed: December 4, 2018
    Publication date: July 11, 2019
    Inventors: Rongsheng E. Wang, Zhigang Lyu, Haley L. Wissler
  • Biosensors for detecting macromolecules and other analytes
    Patent number: 9618505
    Abstract: The invention generally provides two-component molecular biosensors. In particular, the invention provides molecular biosensors having peptide epitope binding agents that bind a target antibody. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Grant
    Filed: February 16, 2015
    Date of Patent: April 11, 2017
    Assignee: MEDIOMICS, LLC
    Inventors: Tomasz Heyduk, Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang
  • BIOSENSORS FOR DETECTING MACROMOLECULES AND OTHER ANALYTES
    Publication number: 20150219668
    Abstract: The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Application
    Filed: February 16, 2015
    Publication date: August 6, 2015
    Applicants: MEDIOMICS LLC, SAINT LOUIS UNIVERSITY
    Inventors: Tomasz Heyduk, Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang
  • Three-component biosensors for detecting macromolecules and other analytes
    Patent number: 8956857
    Abstract: The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Grant
    Filed: December 27, 2012
    Date of Patent: February 17, 2015
    Assignees: Mediomics, LLC, Saint Louis University
    Inventors: Tomasz Heyduk, Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang
  • THREE-COMPONENT BIOSENSORS FOR DETECTING MACROMOLECULES AND OTHER ANALYTES
    Publication number: 20140248710
    Abstract: The invention generally provides three-component molecular biosensors. The molecular biosensors are useful in several methods including in the identification and quantification of target molecules.
    Type: Application
    Filed: December 27, 2012
    Publication date: September 4, 2014
    Applicants: Mediomics LLC, Saint Louis University
    Inventors: Tomasz Heyduk, Ling Tian, Rongsheng E. Wang, Yie-Hwa Chang