Patents by Inventor Roni Mintz

Roni Mintz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SEALANT FORMULATIONS AND USES THEREOF
    Publication number: 20180071429
    Abstract: The invention relates to a storage-stable aqueous sealant formulation comprising a blood derived fibrinogen concentrate, a divalent cation and factor XIa.
    Type: Application
    Filed: September 11, 2017
    Publication date: March 15, 2018
    Inventors: Ronen EAVRI, Amatzia GANTZ, Roni MINTZ, Israel NUR, Damian VISNOVEZKY
  • Immunoglobulin reduced in thrombogenic agents and preparation thereof
    Patent number: 9796770
    Abstract: The invention relates to an immunoglobulin composition reduced in thrombogenic agents and to methods for its preparation. One method comprises subjecting an immunoglobulin containing solution to a negative cation exchanger chromatography at a pH in the range of higher than 3.8 to equal to or lower than 5.3. The solution can also be subjected to a negative anion exchanger chromatography at a pH in the range of 7 to 8.2.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: October 24, 2017
    Assignee: Omrix Biopharmaceuticals Ltd.
    Inventors: Roni Mintz, Oleg Belyaev, Israel Nur, Liliana Bar, Roberto Meidler
  • Immunoassay for thrombin detection
    Patent number: 9329183
    Abstract: The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
    Type: Grant
    Filed: May 12, 2015
    Date of Patent: May 3, 2016
    Assignee: Omrix Biopharmaceuticals Ltd.
    Inventors: Israel Nur, Nadav Orr, Roni Mintz
  • IMMUNOASSAY FOR THROMBIN DETECTION
    Publication number: 20150241430
    Abstract: The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
    Type: Application
    Filed: May 12, 2015
    Publication date: August 27, 2015
    Inventors: Israel Nur, Nadav Orr, Roni Mintz
  • IMMUNOGLOBULIN REDUCED IN THROMBOGENIC AGENTS AND PREPARATION THEREOF
    Publication number: 20150210754
    Abstract: The invention relates to an immunoglobulin composition reduced in thrombogenic agents and to methods for its preparation. One method comprises subjecting an immunoglobulin containing solution to a negative cation exchanger chromatography at a pH in the range of higher than 3.8 to equal to or lower than 5.3. The solution can also be subjected to a negative anion exchanger chromatography at a pH in the range of 7 to 8.2.
    Type: Application
    Filed: April 3, 2015
    Publication date: July 30, 2015
    Inventors: Roni Mintz, Oleg Belyaev, Israel Nur, Liliana Bar, Roberto Meidler
  • Immunoassay for thrombin detection
    Patent number: 9057737
    Abstract: The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: June 16, 2015
    Assignee: Omrix Biopharmaceuticals Ltd.
    Inventors: Roni Mintz, Nadav Orr, Israel Nur
  • Immunoglobulin reduced in thrombogenic agents and preparation thereof
    Patent number: 9023994
    Abstract: The invention relates to an immunoglobulin composition reduced in thrombogenic agents and to methods for its preparation. One method comprises subjecting an immunoglobulin containing solution to a negative cation exchanger chromatography at a pH in the range of higher than 3.8 to equal to or lower than 5.3. The solution can also be subjected to a negative anion exchanger chromatography at a pH in the range of 7 to 8.2.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: May 5, 2015
    Assignee: Omrix Biopharmaceuticals, Ltd.
    Inventors: Roni Mintz, Oleg Belyaev, Israel Nur, Liliana Bar, Roberto Meidler
  • IMMUNOGLOBULIN REDUCED IN THROMBOGENIC AGENTS AND PREPARATION THEREOF
    Publication number: 20120294847
    Abstract: The invention relates to an immunoglobulin composition reduced in thrombogenic agents and to methods for its preparation. One method comprises subjecting an immunoglobulin containing solution to a negative cation exchanger chromatography at a pH in the range of higher than 3.8 to equal to or lower than 5.3. The solution can also be subjected to a negative anion exchanger chromatography at a pH in the range of 7 to 8.2.
    Type: Application
    Filed: May 14, 2012
    Publication date: November 22, 2012
    Applicant: Omrix Biopharmaceuticals Ltd.
    Inventors: Roni MINTZ, Oleg Belyaev, Israel Nur, Liliana Bar, Roberto Meildler
  • IMMUNOASSAY FOR THROMBIN DETECTION
    Publication number: 20120149030
    Abstract: The invention relates to an in vitro immunoassay for quantifying thrombin in a sample comprising anti-thrombin III (AT-III) and thrombin. The method comprises the following steps: contacting the sample with a small molecule that recognizes the substrate binding site of thrombin; contacting the thrombin with a thrombin specific antibody raised against a thrombin blocked in the active site; and measuring the level of bound antibody.
    Type: Application
    Filed: November 30, 2011
    Publication date: June 14, 2012
    Inventors: Roni Mintz, Nadav Orr, Israel Nur
  • Virus Removal by Nanofiltration
    Publication number: 20090186395
    Abstract: A method for purifying a protein solution from infective particles comprising (a) adding a macromolecule to the solution; and (b) passing the solution through a nanofilter. The macromolecule may be selected from a polymer of at least 3 monomers of sugars, amino acids, glycols, alcohols, lipids or phospholipids.
    Type: Application
    Filed: June 25, 2007
    Publication date: July 23, 2009
    Inventors: Israel Nur, Roni Mintz