Patents by Inventor Ronit SHARON

Ronit SHARON has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DETECTION OF PHOSPHOINOSITIDES IN BLOOD CELLS AS A BIOMARKER FOR ALPHA SYNUCLEIN ASSOCIATED PATHOLOGIES AND A METHOD OF TREATMENT OF PARKINSON'S DISEASE AND THE RELATED NEURODEGENERATIONS
    Publication number: 20230288433
    Abstract: The present invention is directed to a method for determining a subject is afflicted with or having increased risk of developing an alpha-synuclein-associated disease or disorder, Parkinson's disease, or both. The method further includes administering to the subject determined as being afflicted with or having increased risk of developing an alpha-synuclein-associated disease or disorder a therapeutically effective amount of an agent characterized by being capable of decreasing signaling transduced by a member of PI4,5P2 PI3,4P2, PI3,5P2, PI3,4,5P3, PI3P, PI4P signal transduction pathway.
    Type: Application
    Filed: December 8, 2022
    Publication date: September 14, 2023
    Applicant: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Ronit SHARON, Meir SCHECHTER, Suad ABD ALHADI
  • DETECTION OF PHOSPHO-SERINE 129 ALPHA-SYNUCLEIN IN BLOOD CELLS AS A BIOMARKER FOR SYNUCLEINOPATHIES
    Publication number: 20210041461
    Abstract: The present invention relates to diagnostic methods and kits for the detection and/or diagnosis of at least one synucleinopathy in a subject. More particularly, the invention provides the use of a-Syn and its post translational modifications, specifically, serine 129 phosphorylated a-Syn, as diagnostic markers for Parkinson's disease specifically, for the diagnosis of PD with motor symptoms (PD-M).
    Type: Application
    Filed: March 14, 2019
    Publication date: February 11, 2021
    Inventor: Ronit SHARON
  • Method for the assay of synucleins
    Patent number: 10534007
    Abstract: The present invention provides a method for the assay of synucleins in a body fluid or tissue sample, wherein said method comprises the steps of contacting said sample with membrane lipids under conditions enabling binding of the synuclein to said lipids, and the detection of the lipid-bound synuclein by a synuclein-binding agent.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: January 14, 2020
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
    Inventor: Ronit Sharon
  • METHOD FOR THE ASSAY OF SYNUCLEINS
    Publication number: 20150024419
    Abstract: The present invention provides a method for the assay of synucleins in a body fluid or tissue sample, wherein said method comprises the steps of contacting said sample with membrane lipids under conditions enabling binding of the synuclein to said lipids, and the detection of the lipid-bound synuclein by a synuclein-binding agent.
    Type: Application
    Filed: October 7, 2014
    Publication date: January 22, 2015
    Inventor: Ronit SHARON