Patents by Inventor Roopa Rai

Roopa Rai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Amido Anti-viral Compounds
    Publication number: 20080181866
    Abstract: Disclosed are compounds, stereoisomers, tautomers, pharmaceutically acceptable salts, or prodrugs thereof of having Formula (I), their preparation, use, and compositions thereof for treating an infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R3, X, V, W, T, Z, R, Y1, and p are as defined herein.
    Type: Application
    Filed: November 20, 2007
    Publication date: July 31, 2008
    Inventors: Martin Robert Leivers, Franz Ulrich Schmitz, Ronald Conrad Griffith, Christopher Don Roberts, Ali Dehghani Mohammad Abadi, Stephanie Anna Chan, Roopa Rai, Irina Slobodov, Tony Loc Ton
  • ANTIVIRAL AGENTS
    Publication number: 20070287699
    Abstract: Compounds are provided having utility for the treatment of viral infections, particularly HCV.
    Type: Application
    Filed: April 30, 2007
    Publication date: December 13, 2007
    Applicant: ViroBay, Inc.
    Inventors: Dange Kumar, Roopa Rai, Wendy Young, Huiyong Hu, Jennifer Riggs, Tony Ton, Michael Green, Barry Hart, Kenneth Brameld, Jeffrey Dener
  • N-(5-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS
    Publication number: 20070265265
    Abstract: Disclosed are compounds having Formula (I) and the compositions and methods thereof for treating or preventing a viral infection mediated at least in part by a virus in the Flaviviridae family of viruses, wherein A, R2, m, R, V, W, T, Z, R1, Y, and p are disclosed herein.
    Type: Application
    Filed: December 12, 2006
    Publication date: November 15, 2007
    Inventors: Franz Schmitz, Christopher Roberts, Ali Dehghani Abadi, Ronald Griffith, Martin Leivers, Irina Slobodov, Roopa Rai
  • Antiviral agents
    Publication number: 20070032522
    Abstract: The present invention is directed to compounds that are antiviral agents. Specifically the compounds of the present invention inhibit replication of HCV and are therefore useful in treating hepatitis C infections. The present invention is also directed to pharmaceutical compositions comprising these compounds and processes for preparing them.
    Type: Application
    Filed: June 28, 2006
    Publication date: February 8, 2007
    Inventors: Dange Kumar, Roopa Rai
  • 2-(2-Hydroxybiphenyl-3-yl)-1h-benzoimidazole-5-carboxamidine derivatives as factor viia inhibitors
    Publication number: 20060205942
    Abstract: The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.
    Type: Application
    Filed: December 3, 2003
    Publication date: September 14, 2006
    Inventors: Aleksandr Kolesnikov, Roopa Rai, William Shrader, Steven Torkelson, Kieron Wesson, Wendy Young
  • 2-[5-(5-carbamimidoyl-1h-heteroaryl)]-6-hydroxybiphenyl-3-yl derivatives as factor viia inhibitors
    Publication number: 20050203094
    Abstract: The present invention provides 2-[5-(5-carbamimidoyl-1H-heteroaryl)]-6-hydroxy-biphenyl-3-yl derivatives of formula (I): I That are Factor VIIa and Xa inhibitors
    Type: Application
    Filed: February 12, 2003
    Publication date: September 15, 2005
    Inventors: Aleksandr Kolesnikov, Roopa Rai, Dvorak Shrader, Wendy Young
  • 2-[5-(5-Carbamimidoyl-1H-heteroaryl)-6-hydroxybiphenyl-3-YL]-succinic acid derivatives as factor viia inhibitors
    Publication number: 20050176797
    Abstract: The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders. Processes for preparing these inhibitors are also disclosed.
    Type: Application
    Filed: September 13, 2004
    Publication date: August 11, 2005
    Applicant: AXYS PHARMACEUTICALS, INC.
    Inventors: Huiyong Hu, John Hendrix, Aleksandr Kolesnikov, Roopa Rai, William Shrader, David Sperandio, Wendy Young, Steven Torkelson
  • (Hetero)aryl-bicyclic heteroaryl derivatives, their preparation and their use as protease inhibitors
    Patent number: 6867200
    Abstract: The present invention provides novel compounds of the Formula (I): A-B, its prodrug forms, or pharmaceutically acceptable salts thereof, wherein A represents a saturated, unsaturated, or a partially unsaturated bicyclic heterocyclic ring structure, and B represents an aryl or a heteroaryl group. Preferred compounds of the present invention comprise a benzimidazole or indole nucleus. The compounds of this invention are inhibitors of serine proteases, Urokinase (uPA), Factor Xa (FXa), and/or Factor VIIa (FVIIa), and have utility as anti cancer agents and/or as anticoagulants for the treatment or prevention of thromboembolic disorders in mammals.
    Type: Grant
    Filed: December 17, 1999
    Date of Patent: March 15, 2005
    Assignee: Axys Pharmaceuticals, Inc.
    Inventors: Darin A. Allen, Jason M. Hataye, Witold N. Hruzewicz, Aleksandr Kolesnikov, Richard L. Mackman, Roopa Rai, Spencer R. Jeffrey, Erik J. Verner, Wendy B. Young, William Dvorak Shrader
  • Non-amidine containing protease inhibitors
    Publication number: 20030225036
    Abstract: The present invention provides novel compounds of the Formula (I) its prodrug forms, or pharmaceutically acceptable salts thereof. Preferred (I) compounds of the present invention comprise a pyrrolo pyridinyl, pyrrolo pyrimidinyl or indole nucleus. The compounds of this invention are inhibitors of Factor Xa (FXa), Factor VIIa (FVIIa) and/or serine proteases, Urokinase (uPA), and have utility as anti-coagulants for the treatment or prevention of thromboembolic disorders in mammals and as anticancer agents.
    Type: Application
    Filed: March 24, 2003
    Publication date: December 4, 2003
    Inventors: Aleksandr Kolesnikov, Roopa Rai
  • 2- [5- (5-carbamimidoyl-1H-heteroaryl)-6-hydroxybiphenyl-3-yl]-succinic acid derivatives as factor viia inhibitors
    Publication number: 20030114457
    Abstract: The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders. Processes for preparing these inhibitors are also disclosed.
    Type: Application
    Filed: July 3, 2002
    Publication date: June 19, 2003
    Applicant: Axys Pharmaceuticals, Inc.
    Inventors: Huiyong Hu, John Hendrix, Aleksandr Kolesnikov, Roopa Rai, William Dvorak Shrader, David Sperandio, Wendy Young, Steve Torkelson