Patents by Inventor Roozsa Gyenge

Roozsa Gyenge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of high-purity 1-(3-chloro-phenyl)-4-methyl-7,8-dimethoxy-5H-2,3-benzodiazepine
    Patent number: 5288863
    Abstract: The invention relates to a process for the preparation of 1-(3-chlorophenyl)-4-methyl-7,8-dimethoxy-5 H-2,3-benzodiazepine of formula (I) ##STR1## in high purity and in a quality suitable for pharmaceutical purposes. According to the invention the reaction of 1 mole of 2-acetonyl-3'-chloro-4,5-dimethoxybenzophenone of formula (II) ##STR2## with 3-7 moles of hydrazine hydrate in an organic solvent or in a mixture of organic solvents at a temperature between 15.degree. C. and 85.degree. C. is carried out in the absence of air oxygen, optionally in the presence of water. The crude product is then recrystallized from an aliphatic alcohol containing 1 to 5 carbon atom(s).
    Type: Grant
    Filed: May 4, 1992
    Date of Patent: February 22, 1994
    Assignee: Egis Gyogyszergyar Rt.
    Inventors: Gyorgy Somogyi, Peter Botka, Gyula Horvath, Antal Simay, Roozsa Gyenge, Imre Moravcsik, Erno Orban, Tamas Hamori, Jeno Korosi, Csilla Kiss, Tibor Balogh, Maria Bidlo nee Igloi, nee Dievald Uskert