Patents by Inventor Rosa E. Mele'ndez

Rosa E. Mele'ndez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Piperidinylamino-Thieno [2,3-D] Pyrimidine Compounds
    Publication number: 20110082157
    Abstract: The invention relates to 5-HT receptor antagonists. Novel piperidinylamino-thieno [2,3-d] pyrimidine compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as pulmonary arterial hypertension, migraine, hypertension, disorders of the gastrointestinal tract, restenosis, asthma, obstructive airway disease, prostatic hyperplasia and priapism, anxiety, depression, schizophrenia, neural injury and stroke. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also provided.
    Type: Application
    Filed: June 8, 2010
    Publication date: April 7, 2011
    Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Sekar A. Reddy, Srinivasa Rao Cheruku, Rosa E. Mele'ndez, Anurag Sharadendu, Dongli Chen, Yael Marantz, Sharon Shacham, Alexander Heifetz, Boaz Inbal, Venkitasamy Kesavan, Shay Bar-Haim
  • Piperidinylamino-thieno[2,3-D] Pyrimidine Compounds
    Publication number: 20100113485
    Abstract: The invention relates to 5-HT receptor modulators, particularly 5-HT2B antagonists. Novel piperidinylamino-thieno[2,3-d]pyrimidine compounds represented by Formula I, II and III, and uses thereof for treating conditions including pulmonary arterial hypertension, congestive heart failure, and hypertension.
    Type: Application
    Filed: October 30, 2009
    Publication date: May 6, 2010
    Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Sekar Reddy Alla, Srinivasa Rao Cheruku, Rosa E. Mele'ndez, Anurag Sharadendu, Dongli Chen, Yael Marantz, Sharon Shacham, Alexander Heifetz, Boaz Inbal, Venkitasamy Kesavan, Shay Bar-Haim
  • Piperidinylamino-thieno[2,3-d] pyrimidine compounds
    Patent number: 7030240
    Abstract: The invention relates to 5-HT receptor antagonists. Novel piperidinylamino-thieno[2,3-d] pyrimidine compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as anxiety, depression, schizophrenia, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.
    Type: Grant
    Filed: March 31, 2004
    Date of Patent: April 18, 2006
    Assignee: Predix Pharmaceuticals Holdings, Inc.
    Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Sekar A. Reddy, Srinivasa Rao Cheruku, Rosa E. Mele'ndez, Anurag Sharadendu, Dongli Chen, Yael Marantz, Sharon Shachem, Alexander Heifetz, Boaz Inbal, Venkitasamy Kesavan, Shay Bar-Haim
  • New piperidinylamino-thieno[2,3-d] pyrimidine compounds
    Publication number: 20040248904
    Abstract: The invention relates to 5-HT receptor antagonists. Novel piperidinylamino-thieno[2,3-d]pyrimidine compounds represented by Formula I, and synthesis and uses thereof for treating diseases mediated directly or indirectly by 5-HT receptors, are disclosed. Such conditions include central nervous system disorders such as anxiety, depression, schizophrenia, neural injury, stroke, and migraine. Methods of preparation and novel intermediates and pharmaceutical salts thereof are also included.
    Type: Application
    Filed: March 31, 2004
    Publication date: December 9, 2004
    Inventors: Dale S. Dhanoa, Oren Becker, Silvia Noiman, Sekar A. Reddy, Srinivasa Rao Cheruku, Rosa E. Mele'ndez, Anurag Sharadendu, Dongli Chen, Yael Marantz, Sharon Shachem, Alexander Heifetz, Boaz Inbal, Venkitasamy Kesavan, Shay Bar-Haim