Patents by Inventor Rosa Hernandez
Rosa Hernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20240131152Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.Type: ApplicationFiled: October 2, 2023Publication date: April 25, 2024Inventors: Luis Enrique Fernández Molina, Belinda Sánchez Ramírez, Audry Fernández Gómez, Gretchen Bergado Báez, Circe Mesa Pardillo, Lisset Chao García, Narjara González Suárez, Dayana Pérez Martínez, Diana Rosa Hernández Fernández, Mabel Cruz Rodríguez, Ángel Alexis Manso Vargas, Vicente Guillermo Verez Bencomo, Blanca Idelmis Tolón Murguía, Miguel Antonio López López, Jesús Arturo Junco Barranco
-
Patent number: 11806396Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.Type: GrantFiled: October 24, 2018Date of Patent: November 7, 2023Assignee: Centro de Inmunología MolecularInventors: Luis Enrique Fernández Molina, Belinda Sánchez Ramírez, Audry Fernández Gómez, Gretchen Bergado Báez, Circe Mesa Pardillo, Lisset Chao García, Narjara González Suárez, Dayana Pérez Martínez, Diana Rosa Hernández Fernández, Mabel Cruz Rodríguez, Ángel Alexis Manso Vargas, Vicente Guillermo Verez Bencomo, Blanca Idelmis Tolón Murguía, Miguel Antonio López López, Jesús Arturo Junco Barranco
-
Patent number: 11746426Abstract: Aspects included herein include an electrolytic system for electrochemical reduction of carbon dioxide, the system comprising: a cathode comprising: a porous gas-diffusion membrane permeable to CO2; an electrocatalyst layer adjacent to a second side of the gas-diffusion membrane; the electrocatalyst layer comprising: an electrically conductive catalyst; and a selectivity-determining organic material attached to at least a portion of the electrically conductive catalyst; wherein: the organic material is formed of a plurality of oligomers; each oligomer comprises a plurality of covalently bonded base units; each base unit comprises at least one heterocyclic group having at least one nitrogen in its structure; and an anion exchange membrane adjacent to the electrocatalyst layer and positioned between the anode and the cathode; wherein anion exchange membrane is characterized by anion conductivity and the cathode is in ionic communication with the anode via the anion exchange membrane.Type: GrantFiled: July 10, 2020Date of Patent: September 5, 2023Assignees: California Institute of Technology, The Governing Council of the University of TorontoInventors: Theodor Agapie, Alonso Rosas-Hernandez, Fengwang Li, Jonas C. Peters, Edward H. Sargent, Arnaud Thevenon
-
Publication number: 20220380911Abstract: A CO2 reduction system has a cathode in contact with a catholyte. The cathode includes a selectivity-determining layer on an electron conductor. The selectivity-determining layer includes a selectivity-determining component that includes a substituted heterocycle.Type: ApplicationFiled: June 9, 2022Publication date: December 1, 2022Inventors: Zhiji Han, Ruud Kortlever, Hsiang-Yun Chen, Jonas C. Peters, Theodor Agapie, Jorge A. Rosas Hernandez, Arnaud A. Thevenon
-
Patent number: 11371152Abstract: A CO2 reduction system has a cathode in contact with a catholyte. The cathode includes a selectivity-determining layer on an electron conductor. The selectivity-determining layer includes a selectivity-determining component that includes a substituted heterocycle.Type: GrantFiled: April 10, 2018Date of Patent: June 28, 2022Assignee: California Institute of TechnologyInventors: Zhiji Han, Ruud Kortlever, Hsiang-Yun Chen, Jonas C. Peters, Theodor Agapie, Jorge A. Rosas Hernandez, Arnaud A. Thevenon
-
Publication number: 20210062349Abstract: Aspects included herein include an electrolytic system for electrochemical reduction of carbon dioxide, the system comprising: a cathode comprising: a porous gas-diffusion membrane permeable to CO2; an electrocatalyst layer adjacent to a second side of the gas-diffusion membrane; the electrocatalyst layer comprising: an electrically conductive catalyst; and a selectivity-determining organic material attached to at least a portion of the electrically conductive catalyst; wherein: the organic material is formed of a plurality of oligomers; each oligomer comprises a plurality of covalently bonded base units; each base unit comprises at least one heterocyclic group having at least one nitrogen in its structure; and an anion exchange membrane adjacent to the electrocatalyst layer and positioned between the anode and the cathode; wherein anion exchange membrane is characterized by anion conductivity and the cathode is in ionic communication with the anode via the anion exchange membrane.Type: ApplicationFiled: July 10, 2020Publication date: March 4, 2021Inventors: Theodor AGAPIE, Alonso ROSAS-HERNANDEZ, Fengwang LI, Jonas C. PETERS, Edward H. SARGENT, Arnaud THEVENON
-
Publication number: 20200268878Abstract: This invention describes ways of obtaining nano-particulated adjuvants formed by different synthetic variants of GM3 ganglioside. Depending on the fine structure of the fatty acid in the ceramide of the synthetic GM3, said adjuvants are able to stimulate specifically and in a specialized way the humoral or cellular immune response against accompanying antigens. Particularly, this invention provides immunogenic vaccine compositions that comprise peptides, polypeptides or proteins and the aforementioned nanoparticles, which are formed through the dispersion of hydrophobic proteins of the outer membrane complex (OMC) of Neisseria meningitidis in solutions containing fully synthetic variants of the GM3 ganglioside.Type: ApplicationFiled: October 24, 2018Publication date: August 27, 2020Inventors: Luis Enrique Fernández Molina, Belinda Sánchez Ramírez, Audry Fernández Gómez, Gretchen Bergado Báez, Circe Mesa Pardillo, Lisset Chao García, Narjara González Suárez, Dayana Pérez Martínez, Diana Rosa Hernández Fernández, Mabel Cruz Rodríguez, Ángel Alexis Manso Vargas, Vicente Guillermo Verez Bencomo, Blanca Idelmis Tolón Murguía, Miguel Antonio López López, Jesús Arturo Junco Barranco
-
Publication number: 20200011870Abstract: The present invention relates to the branch of Biotechnology and Medicine, particularly to a method for the selection and treatment of patients with carcinomas of epithelial origin that co-express the HER1 and HER2 receptors without increased expression of these receptors or with the presence of RAS activating mutations. In particular, this method is based on the application of bivalent vaccine compositions which have as active principle the extracellular domains of the HER1 and HER2 receptors or portions thereof and as an adjuvant the very small proteoliposomes derived from the outer membrane proteins of Neisseria meningitidis and the GM3 ganglioside. This method is useful for the treatment of patients whose expression levels of HER1 and HER2 do not allow the monoclonal antibodies against HER1 and/or HER2 to have a therapeutic effect.Type: ApplicationFiled: March 8, 2018Publication date: January 9, 2020Inventors: BELINDA SÁNCHEZ RAMÍREZ, GRETCHEN BÁEZ BERGADO, NARJARA GONZÁLEZ SUÁREZ, MABEL CRUZ RODRÍGUEZ, DIANA ROSA HERNÁNDEZ FERNÁNDEZ, LISSET CHAO GARCÍA
-
Publication number: 20180291515Abstract: A CO2 reduction system has a cathode in contact with a catholyte. The cathode includes a selectivity-determining layer on an electron conductor. The selectivity-determining layer includes a selectivity-determining component that includes a substituted heterocycle.Type: ApplicationFiled: April 10, 2018Publication date: October 11, 2018Inventors: Zhiji Han, Ruud Kortlever, Hsiang-Yun Chen, Jonas C. Peters, Theodor Agapie, Jorge A. Rosas Hernandez, Arnaud A. Thevenon
-
Publication number: 20070293839Abstract: The absorbent article provides a signal viewable from the top surface of the absorbent article which gives a perception of depth within the absorbent article. This creation of depth perception is accomplished by the use of at least two tones within a color and/or by the use of multiple tones and multiple colors operating together to create a perception of depth within the absorbent article.Type: ApplicationFiled: August 20, 2007Publication date: December 20, 2007Inventors: Patricia Christon, Bryan Feller, Ronda Glassmeyer, Rosa Hernandez
-
Publication number: 20070016154Abstract: The absorbent article provides a signal viewable from the top surface of the absorbent article which gives a perception of depth within the absorbent article. This creation of depth perception is accomplished by the use of at least two tones within a color and/or by the use of multiple tones and multiple colors operating together to create a perception of depth within the absorbent article.Type: ApplicationFiled: September 22, 2006Publication date: January 18, 2007Inventors: Patricia Christon, Bryan Feller, Ronda Glassmeyer, Rosa Hernandez
-
Publication number: 20060240111Abstract: Semisolid mucoadhesive formulations for vaginal application, with improved technical and organoleptic characteristics, which contain at least two bioadhesive gelling polymers and an active ingredient, useful in the prevention and/or treatment of various pathologies and disorders in human beings or animals.Type: ApplicationFiled: July 16, 2004Publication date: October 26, 2006Inventors: Alvaro Fernández, Ana Garcia, Rosa Hernández Martin, Manuela Igartua Olaechea, José Pedraz Muñoz, Alicia Rodriguez Gascón
-
Publication number: 20050124955Abstract: The absorbent article provides a signal viewable from the top surface of the absorbent article which gives a perception of depth within the absorbent article. This creation of depth perception is accomplished by the use of at least two tones within a color and/or by the use of multiple tones and multiple colors operating together to create a perception of depth within the absorbent article. At least one tone contains a graphic.Type: ApplicationFiled: October 18, 2004Publication date: June 9, 2005Inventors: Dannette Adams, Forrest Maloney, Patricia Christon, Bryan Feller, Ronda Glassmeyer, Rosa Hernandez
-
Publication number: 20050124954Abstract: The absorbent article provides a signal viewable from the top surface of the absorbent article which gives a perception of depth within the absorbent article. This creation of depth perception is accomplished by the use of at least two tones within a color and/or by the use of multiple tones and multiple colors operating together to create a perception of depth within the absorbent article. At least one tone contains a graphic.Type: ApplicationFiled: October 18, 2004Publication date: June 9, 2005Inventors: Dannette Adams, Forrest Maloney, Patricia Christon, Bryan Feller, Ronda Glassmeyer, Rosa Hernandez
-
Publication number: 20050038402Abstract: The absorbent article provides a signal viewable from the top surface of the absorbent article which gives a perception of depth within the absorbent article. This creation of depth perception is accomplished by the use of at least two tones within a color and/or by the use of multiple tones and multiple colors operating together to create a perception of depth within the absorbent article.Type: ApplicationFiled: September 20, 2004Publication date: February 17, 2005Inventors: Patricia Christon, Bryan Feller, Ronda Glassmeyer, Rosa Hernandez