Abstract: A flight planning system and method include one or more control units configured to determine, from ensemble data, a plurality of flight plans for an aircraft from a departure location to an arrival location. The ensemble data includes an aggregation of data from multiple data sources. In at least one example, the one or more control units are further configured to determine a preferred flight plan from the plurality of flight plans.

Abstract: The present invention relates to a compound of formula I, HetAr is a five or six membered heteroaryl group, selected from wherein R1 is hydrogen, halogen, lower alkyl, lower alkoxy or lower alkyl substituted by halogen, and may be the same or different, if two R1 occur; R2 is lower alkyl or a mono- or polydeutered derivative thereof, lower alkyl substituted by halogen or lower alkoxy, lower alkenyl unsubstituted or substituted by halogen, cycloalkyl or CH2-cycloalkyl unsubstituted or substituted by halogen, heterocycloalkyl or CH2-heterocycloalkyl unsubstituted or substituted by lower alkyl; R3 is halogen, lower alkyl, lower alkyl substituted by halogen, lower alkoxy substituted by halogen or S(O)2-lower alkyl; n is 1, 2 or 3; if n is >1, then R3 may be the same or different; or to a pharmaceutically active acid addition salt thereof, to a racemic mixture or to its corresponding enantiomer and/or an optical isomer and/or stereoisomer thereof.

Abstract: A system for mid-fidelity simulation may include a memory configured to store data representing a flight scenario. The system may further include a display device configured to present a graphical user interface to a user, the graphical user interface including representations of a first set of control interfaces, the first set of control interfaces including one or more features that are common between multiple aircraft, the graphical user interface omitting one or more features of the first set of control interfaces that are not common between the multiple aircraft. The system may also include a processor configured to perform a simulation of the flight scenario while receiving user input and displaying user output via the representations of the first set of control interfaces.

Abstract: The present invention relates to a compound of formula I, HetAr is a five or six membered heteroaryl group, selected from wherein R1 is hydrogen, halogen, lower alkyl, lower alkoxy or lower alkyl substituted by halogen, and may be the same or different, i-f two R1 occur; R2 is lower alkyl or a mono- or polydeutered derivative thereof, lower alkyl substituted by halogen or lower alkoxy, lower alkenyl unsubstituted or substituted by halogen, cycloalkyl or CH2-cycloalkyl unsubstituted or substituted by halogen, heterocycloalkyl or CH2-heterocycloalkyl unsubstituted or substituted by lower alkyl; R3 is halogen, lower alkyl, lower alkyl substituted by halogen, lower alkoxy substituted by halogen or S(0)2-lower alkyl; n is 1, 2 or 3; if n is >1, then R3 may be the same or different; or to a pharmaceutically active acid addition salt thereof, to a racemic mixture or to its corresponding enantiomer and/or an optical isomer and/or stereoisomer thereof.

Abstract: The present invention relates to compounds of formula wherein HetAr is a five or six membered hetaryl group, containing one, two or three heteroatoms, selected from N, O or S; R1 is hydrogen, lower alkyl, lower alkyl substituted by halogen, halogen or lower alkoxy; R2 is lower alkyl substituted by halogen; R3 is hydrogen, lower alkyl substituted by halogen, lower alkyl or lower alkyl substituted by hydroxy; Y is R4 is lower alkoxy, lower alkoxy substituted by halogen or CN; or to pharmaceutically active acid addition salts thereof, to racemic mixtures or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof. The compounds may be used for the treatment of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica or Down syndrome.

Abstract: The present invention relates to a compound of formula wherein HetAr is a five or six membered hetaryl group, containing one, two or three heteroatoms, selected from N, O or S; R1 is hydrogen, lower alkyl, lower alkyl substituted by halogen, halogen, or lower alkoxy; R2 is lower alkyl substituted by halogen, —CH2—C3-6-cycloalkyl, substituted by one or two substituents, selected from lower alkyl substituted by halogen or halogen, or is lower alkenyl substituted by halogen; R3 is hydrogen, lower alkyl substituted by halogen, lower alkyl, halogen, C3-6-cycloalkyl or lower alkyl substituted by hydroxy; n is 1 or 2; for n=2, R1 can be independent to each other; Y is CH or N; or to a pharmaceutically active acid addition salt thereof, to a racemic mixture or its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof.

Abstract: A system and method for verifying ADS-B messages received at an aircraft from other aircraft within its ADS-B range. This disclosure enhances the current Automatic Dependent Surveillance-Broadcast (ADS-B) IN surveillance systems, and the disclosed system is an onboard system designed to enable ADS-B IN capable aircraft to verify the information received via ADS-B from the rest of the aircraft within its ADS-B range. The system's performance is based on the principles of multilateration (MLAT). The system performs MLAT calculations to determine whether the ADS-B messages received are truthful or not truthful. The disclosed system relies on a communication protocol based on a series of requests and responses to interchange the information needed by the aircraft involved in the process to carry out the MLAT calculations.

Abstract: A system for mid-fidelity simulation may include a memory configured to store data representing a flight scenario. The system may further include a display device configured to present a graphical user interface to a user, the graphical user interface including representations of a first set of control interfaces, the first set of control interfaces including one or more features that are common between multiple aircraft, the graphical user interface omitting one or more features of the first set of control interfaces that are not common between the multiple aircraft. The system may also include a processor configured to perform a simulation of the flight scenario while receiving user input and displaying user output via the representations of the first set of control interfaces.

Abstract: The present invention relates to compounds of formula hetaryl is a five membered heteroaryl group, containing 1 to 3 heteroatoms, selected from O, S or N; R1 is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkyl substituted by halogen, S-lower alkyl substituted by halogen or lower alkoxy substituted by halogen, or two neighboring carbon atoms may form on phenyl an additional ring containing —O—CH2—O—; n is 1 to 5; R2 is hydrogen or lower alkyl substituted by halogen; R3 is hydrogen or lower alkyl substituted by halogen; or to pharmaceutically active acid addition salts thereof, to racemic mixtures or to its corresponding enantiomers or optical isomers or stereoisomers thereof. The compounds may be used for the treatment of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica or Down syndrome.

Abstract: The present invention relates to a compound of formula wherein HetAr is a five or six membered hetaryl group, containing one, two or three heteroatoms, selected from N, O or S; R1 is hydrogen, lower alkyl, lower alkyl substituted by halogen, halogen, or lower alkoxy; R2 is lower alkyl substituted by halogen, —CH2—C3-6-cycloalkyl, substituted by one or two substituents, selected from lower alkyl substituted by halogen or halogen, or is lower alkenyl substituted by halogen; R3 is hydrogen, lower alkyl substituted by halogen, lower alkyl, halogen, C3-6-cycloalkyl or lower alkyl substituted by hydroxy; n is 1 or 2; for n=2, R1 can be independent to each other; Y is CH or N; or to a pharmaceutically active acid addition salt thereof, to a racemic mixture or its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof.

Abstract: Described are systems and methods of aircraft surveillance and tracking. A method for aircraft tracking includes partitioning an airspace region into multiple sectors and generating multiple data structures corresponding respectively to each of the multiple sectors. Each data structure has a primary identifier and at least one secondary identifier that matches the primary identifier corresponding to the at least one other sector. The method includes receiving at least one data packet from an aircraft located within one of the multiple sectors, storing the aircraft data from the data packet within the data structure corresponding to the one of the sectors, storing the aircraft data within each of the data structures that has a secondary identifier matching the primary identifier, and for each of the multiple sectors, sending each aircraft within the sector aircraft data stored within the data structure corresponding to the sector.

Abstract: An apparatus, medium, and method including receiving transaction details related to a purchase transaction from a first user, the transaction details including at least a purchase amount; receiving a request to split the purchase amount between multiple users, the multiple users including the first user; dividing the purchase amount between the multiple users; and completing the purchase transaction directly with the multiple users in accordance with the purchase amount divided between the multiple users and a payment account device associated with each of the multiple users.

Abstract: The present invention relates to compounds of formula wherein HetAr is a five or six membered hetaryl group, containing one, two or three heteroatoms, selected from N, O or S; R1 is hydrogen, lower alkyl, lower alkyl substituted by halogen, halogen or lower alkoxy; R2 is lower alkyl substituted by halogen; R3 is hydrogen, lower alkyl substituted by halogen, lower alkyl or lower alkyl substituted by hydroxy; Y is R4 is lower alkoxy, lower alkoxy substituted by halogen or CN; or to pharmaceutically active acid addition salts thereof, to racemic mixtures or to its corresponding enantiomers and/or optical isomers and/or stereoisomers thereof. The compounds may be used for the treatment of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica or Down syndrome.

Abstract: The present invention relates to a compound of formula wherein HetAr is a five or six membered hetaryl group, containing one, two or three heteroatoms, selected from N, O or S; R1 is hydrogen, lower alkyl, lower alkyl substituted by halogen, halogen, or lower alkoxy; R2 is lower alkyl substituted by halogen, —CH2—C3-6-cycloalkyl, substituted by one or two substituents, selected from lower alkyl substituted by halogen or halogen, or is lower alkenyl substituted by halogen; R3 is hydrogen, lower alkyl substituted by halogen, lower alkyl, halogen, C3-6-cycloalkyl or lower alkyl substituted by hydroxy; n is 1 or 2; for n=2, R1 can be independent to each other; Y is CH or N; or to a pharmaceutically active acid addition salt thereof, to a racemic mixture or its corresponding enantiomer and/or optical isomer and/or stereoisomer thereof.

Abstract: A device and a method for monitoring continuously the activity of a microphone and a speaker of an electronic communications device, filtering any emitted or received signal in the ultrasound frequency spectrum (signals ?17 kHz) and assessing whether the emitted or received signal is malicious or benign, in order to detect and avoid malicious transmissions established on the ultrasounds frequency spectrum. If a malicious transmission is detected, the user is alerted and can allow or deny said transmission. The device and method are a new concept of Information Technology defense systems that complements traditional antivirus.

Abstract: The present invention relates to compounds of formula hetaryl is a five membered heteroaryl group, containing 1 to 3 heteroatoms, selected from O, S or N; R1 is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkyl substituted by halogen, S-lower alkyl substituted by halogen or lower alkoxy substituted by halogen, or two neighboring carbon atoms may form on phenyl an additional ring containing —O—CH2—O—; n is 1 to 5; R2 is hydrogen or lower alkyl substituted by halogen; R3 is hydrogen or lower alkyl substituted by halogen; or to pharmaceutically active acid addition salts thereof, to racemic mixtures or to its corresponding enantiomers or optical isomers or stereoisomers thereof. The compounds may be used for the treatment of Alzheimer's disease, cerebral amyloid angiopathy, hereditary cerebral hemorrhage with amyloidosis, Dutch-type (HCHWA-D), multi-infarct dementia, dementia pugilistica or Down syndrome.

Abstract: The disclosure provides a computer-implemented method of processing information to use when producing a mission plan to accomplish a mission. The example method includes obtaining one or more mission goals to be achieved during execution of the mission and obtaining information relating to one or more resources to be used during execution of the mission. The information relating to at least one of the resources includes uncertainty. The example method also includes obtaining user preferences relating to how the uncertainty is to be handled, transforming the information relating to the one or more resources according to the user preferences to reduce the uncertainty in the information and providing the transformed information to a smart process manager, for use by the smart process manager to identify one or more of the resources that are to be used to execute at least one mission step as part of at least one mission plan to achieve the one or more mission goals and accomplish the mission.

Abstract: Mobile multilateration systems and related methods are disclosed. An example method includes accessing multilateration data relating to a first aircraft using a time-difference-of-arrival determiner of a second aircraft; processing the multilateration data at the second aircraft to determine a calculated position of the first aircraft; comparing the calculated position of the first aircraft to an asserted position of the first aircraft stored at the second aircraft; and in response to the comparison, determining if the calculated position and the asserted position are within a threshold of one another using the time-difference-of-arrival determiner of the second aircraft to determine an authenticity of the first aircraft.

Abstract: Described are systems and methods of aircraft surveillance and tracking. A method for aircraft tracking includes partitioning an airspace region into multiple sectors and generating multiple data structures corresponding respectively to each of the multiple sectors. Each data structure has a primary identifier and at least one secondary identifier that matches the primary identifier corresponding to the at least one other sector. The method includes receiving at least one data packet from an aircraft located within one of the multiple sectors, storing the aircraft data from the data packet within the data structure corresponding to the one of the sectors, storing the aircraft data within each of the data structures that has a secondary identifier matching the primary identifier, and for each of the multiple sectors, sending each aircraft within the sector aircraft data stored within the data structure corresponding to the sector.

Abstract: A system and method for verifying ADS-B messages received at an aircraft from other aircraft within its ADS-B range. This disclosure enhances the current Automatic Dependent Surveillance-Broadcast (ADS-B) IN surveillance systems, and the disclosed system is an onboard system designed to enable ADS-B IN capable aircraft to verify the information received via ADS-B from the rest of the aircraft within its ADS-B range. The system's performance is based on the principles of multilateration (MLAT). The system performs MLAT calculations to determine whether the ADS-B messages received are truthful or not truthful. The disclosed system relies on a communication protocol based on a series of requests and responses to interchange the information needed by the aircraft involved in the process to carry out the MLAT calculations.