Patents by Inventor Rosalind Kim

Rosalind Kim has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8105983
    Abstract: An optimum solubility screen in which a panel of buffers and many additives are provided in order to obtain the most homogeneous and monodisperse protein condition for protein crystallization. The present methods are useful for proteins that aggregate and cannot be concentrated prior to setting up crystallization screens. A high-throughput method using the hanging-drop method and vapor diffusion equilibrium and a panel of twenty-four buffers is further provided. Using the present methods, 14 poorly behaving proteins have been screened, resulting in 11 of the proteins having highly improved dynamic light scattering results allowing concentration of the proteins, and 9 were crystallized.
    Type: Grant
    Filed: March 29, 2006
    Date of Patent: January 31, 2012
    Assignee: The Regents of the University of California
    Inventors: Sung-Hou Kim, Rosalind Kim, Jamila Jancarik
  • Publication number: 20060223120
    Abstract: Herein is described and optimum solubility screen in which a panel of buffers and many additives are provided in order to obtain the most homogeneous and monodisperse protein condition for protein crystallization. The present methods are useful for proteins that aggregate and cannot be concentrated prior to setting up crystallization screens. A broad range of buffers is intended for use in this screen. A high-throughput method using the hanging-drop method and vapor diffusion equilibrium and a panel of twenty-four buffers is further provided. After monitoring precipitation, the conditions leading to clear drops are selected for evaluation, preferably dynamic light scattering (DLS) characterization. If the DLS results are not optimal, a series of additives are tested in the presence of the best buffer selected from the initial screen and again DLS is used to determine the best condition.
    Type: Application
    Filed: March 29, 2006
    Publication date: October 5, 2006
    Inventors: Sung-Hou Kim, Rosalind Kim, Jamila Jancarik
  • Patent number: 5739409
    Abstract: Edible fruit, seed and vegetables of transgenic plants modified to produce a sweetening protein such as monellin or thaumatin are useful in preparing food compositions which have enhanced sweetness improved flavor. Expression systems for the genes encoding sweetening proteins compatible with plant systems and designed to enhance the production of these proteins in the edible portions of plants, and methods for producing sweetened fruit, seeds and vegetables are described.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: April 14, 1998
    Assignees: The Regents of the University of California, Lucky Biotech Corp.
    Inventors: Robert Fischer, Sung-Hou Kim, Joong Myung Cho, Lola Penarrubia, James Giovannoni, Rosalind Kim
  • Patent number: 5234834
    Abstract: Edible fruit, seed and vegetables of transgenic plants modified to produce a sweetening protein such as monellin or thaumatin are useful in preparing food compositions which have enhanced sweetness improved flavor. Expression systems for the genes encoding sweetening proteins compatible with plant systems and designed to enhance the production of these proteins in the edible portions of plants, and methods for producing sweetened fruit, seeds and vegetables are described.
    Type: Grant
    Filed: July 24, 1990
    Date of Patent: August 10, 1993
    Assignees: The Regents of the University of California, Lucky Biotech Corp.
    Inventors: Robert Fischer, Sung-Hou Kim, Joong M. Cho, Lola Penarrubia, James Giovannoni, Rosalind Kim