Patents by Inventor Rosamund Chapman

Rosamund Chapman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Production of soluble HIV envelope trimers in planta
    Patent number: 10899801
    Abstract: The present invention relates to a method for producing a recombinant HIV glycoprotein polypeptide in a plant and to trimeric complexes of the recombinant, plant-produced HIV glycoprotein polypeptide which mimic the native HIV Env complex. The invention also relates to nucleic acids encoding the recombinant polypeptides, expression vectors containing the aforementioned nucleic acids and to pharmaceutical compositions, uses and methods of eliciting an immune response against HIV in a subject using the recombinant polypeptides and trimeric complexes.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: January 26, 2021
    Assignee: University of Cape Town
    Inventors: Ann Elizabeth Meyers, Anna-Lise Williamson, Edward Peter Rybicki, Emmanuel Aubrey Margolin, Rosamund Chapman
  • PRODUCTION OF SOLUBLE HIV ENVELOPE TRIMERS IN PLANTA
    Publication number: 20190337994
    Abstract: The present invention relates to a method for producing a recombinant HIV glycoprotein polypeptide in a plant and to trimeric complexes of the recombinant, plant-produced HIV glycoprotein polypeptide which mimic the native HIV Env complex. The invention also relates to nucleic acids encoding the recombinant polypeptides, expression vectors containing the aforementioned nucleic acids and to pharmaceutical compositions, uses and methods of eliciting an immune response against HIV in a subject using the recombinant polypeptides and trimeric complexes.
    Type: Application
    Filed: October 13, 2017
    Publication date: November 7, 2019
    Inventors: Ann Elizabeth Meyers, Anna-Lise Williamson, Edward Peter Rybicki, Emmanuel Aubrey Margolin, Rosamund Chapman