Patents by Inventor Rosann M. Kaylor
Rosann M. Kaylor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8377379Abstract: A lateral flow assay device includes a housing, and a test strip disposed within the housing having a membrane with a detection region and a collection region. A sample meter includes a first end for absorption of a test sample, and a storage section that receives and stores at least a component of the test sample. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed adjacent the collection region of the membrane. The test sample component is transferable from the storage section to the collection region for subsequent migration to the detection region. An activatable isolation mechanism is provided within the housing and is disposed so as to isolate portions of the sample meter storage section upon activation thereof such that a defined length of the storage section is presented to the collection region of the membrane.Type: GrantFiled: December 15, 2006Date of Patent: February 19, 2013Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Shawn R. Feaster, Kaiyuan Yang, Ning Wei, Chibueze O. Chidebelu-Eze, James M. Takeuchi, Rosann M. Kaylor, Enrico L. DiGiammarino, Jeffrey E. Fish
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Patent number: 7838258Abstract: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.Type: GrantFiled: September 30, 2009Date of Patent: November 23, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Kaiyuan Yang, Shawn R. Feaster, Ning Wei, Rosann M. Kaylor, Chibueze O. Chidebelu-Eze
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Patent number: 7775991Abstract: A blood sampling device includes a lancet having a skin piercing member disposed at an end thereof. The lancet is slidable within and releasably engaged with an elongated lancet guide that remains stationary with use of the device. A shell is axially movable relative to the lancet guide between a rest position and an actuate position, with the lancet being spring loaded within the lancet guide by movement of the shell from the rest position to the actuate position.Type: GrantFiled: August 31, 2005Date of Patent: August 17, 2010Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Shawn R. Feaster, Rosann M. Kaylor, David S. Cohen, Udo Leuschner, Michael Strehl
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Publication number: 20100015658Abstract: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.Type: ApplicationFiled: September 30, 2009Publication date: January 21, 2010Applicant: KIMBERLY-CLARK WORLDWIDE, INCInventors: Kaiyuan Yang, Shawn R. Feaster, Ning Wei, Rosann M. Kaylor, Chibueze O. Chidebelu-Eze
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Patent number: 7618810Abstract: A diagnostic method and associated test kit for detecting an analyte residing in a test sample is provided. The kit includes a housing, and a membrane disposed within the housing having a detection region and a collection region. A blood sample meter is provided having a first end for absorption of a blood sample, a filtering section adjacent to the first end that filters red blood cell components from the blood sample, and a storage section adjacent to the filtering section that receives plasma or serum from the filtering section. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed in fluid communication with the collection region of the membrane. The plasma or serum is transferred from the storage section of the sample meter to the collection region of the membrane for subsequent migration to the detection region.Type: GrantFiled: December 14, 2005Date of Patent: November 17, 2009Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Kaiyuan Yang, Shawn R. Feaster, Ning Wei, Rosann M. Kaylor, Chibueze O. Chidebelu-Eze
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Publication number: 20080145272Abstract: A lateral flow assay device includes a housing, and a test strip disposed within the housing having a membrane with a detection region and a collection region. A sample meter includes a first end for absorption of a test sample, and a storage section that receives and stores at least a component of the test sample. An opening in the housing is sized for insertion of the sample meter into the housing such that the storage section of the sample meter is disposed adjacent the collection region of the membrane. The test sample component is transferable from the storagesection to the collection region for subsequent migration to the detection region. An activatable isolation mechanism is provided within the housing and is disposed so as to isolate portions of the sample meter storage section upon activation thereof such that a defined length of the storage section is presented to the collection region of the membrane.Type: ApplicationFiled: December 15, 2006Publication date: June 19, 2008Inventors: Shawn R. Feaster, Kaiyuan Yang, Ning Wei, Chibueze O. Chidebelu-Eze, James M. Takeuchi, Rosann M. Kaylor, Enrico L. DiGiammarino, Jeffrey E. Fish
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Patent number: 7091049Abstract: An enhanced diffraction based biosensor system and method are provided for detecting an analyte of interest in a test medium. The system incorporates at least one additional detection tag substance with the analyte of interest, the tag emitting a measurable parameter that is different from optical diffraction characteristics of the analyte. The biosensor may be a “fluoroptical” system wherein the detection tag is a fluorescence emitting substance, including fluorescent-labeled diffraction enhancing elements. The enhanced diffraction biosensor system may determine the presence of analytes in biological fluids both qualitatively and quantitatively.Type: GrantFiled: June 26, 2002Date of Patent: August 15, 2006Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Rameshbabu Boga, Chibueze Obinna Chidebelu-Eze, Rosann M. Kaylor, Xuedong Song
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Publication number: 20040002110Abstract: An enhanced diffraction based biosensor system and method are provided for detecting an analyte of interest in a test medium. The system incorporates at least one additional detection tag substance with the analyte of interest, the tag emitting a measurable parameter that is different from optical diffraction characteristics of the analyte. The biosensor may be a “fluoroptical” system wherein the detection tag is a fluorescence emitting substance, including fluorescent-labeled diffraction enhancing elements. The enhanced diffraction biosensor system may determine the presence of analytes in biological fluids both qualitatively and quantitatively.Type: ApplicationFiled: June 26, 2002Publication date: January 1, 2004Applicant: KIMBERLY-CLARK WORLDWIDE, INC.Inventors: Rameshbabu Boga, Chibueze Obinna Chidebelu-Eze, Rosann M. Kaylor, Xuedong Song
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Patent number: 6579673Abstract: The present invention provides an inexpensive and sensitive device and method for detecting and quantifying analytes present in a medium. The device comprises a metalized film upon which is printed a specific, predetermined pattern of an antibody-binding proteins. Upon attachment of a target analyte to select areas of the plastic film upon which the protein is printed, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.Type: GrantFiled: December 17, 1998Date of Patent: June 17, 2003Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Kevin McGrath, Rosann M. Kaylor, Dennis S. Everhart
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Patent number: 6573040Abstract: The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as functionalized microspheres, which are modified such that they are capable of binding with a target analyte. Additionally, the system comprises a polymer film, which may include a metal coating, upon which is printed a specific, predetermined pattern of a analyte-specific receptors. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.Type: GrantFiled: December 8, 2000Date of Patent: June 3, 2003Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Dennis S. Everhart, Rosann M. Kaylor, Kevin McGrath
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Patent number: 6399295Abstract: The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as functionalized microspheres, which are modified such that they are capable of binding with a target analyte. Additionally, the system comprises a polymer film, which may include a metal coating, upon which is printed a specific, predetermined pattern of a analyte-specific receptors. Finally, the system includes a wicking agent which permits the system to be a single step system which avoids the necessity of any additional rinsing steps. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image, such as a hologram, is produced which can be easily seen with the eye or, optionally, with a sensing device.Type: GrantFiled: December 17, 1999Date of Patent: June 4, 2002Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Rosann M. Kaylor, Abraham B. Choi, Chibueze Obinna Chidebelu-Eze, Michael Heinrich Herbert Grunze
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Publication number: 20010055754Abstract: The present invention provides an inexpensive and sensitive device and method for detecting and quantifying analytes present in a medium. The device comprises a metalized film upon which is printed a specific, predetermined pattern of an antibody-binding proteins. Upon attachment of a target analyte to select areas of the plastic film upon which the protein is printed, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.Type: ApplicationFiled: December 17, 1998Publication date: December 27, 2001Inventors: KEVIN MCGRATH, ROSANN M. KAYLOR, DENNIS EVERHART
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Publication number: 20010004526Abstract: The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as functionalized microspheres, which are modified such that they are capable of binding with a target analyte. Additionally, the system comprises a polymer film, which may include a metal coating, upon which is printed a specific, predetermined pattern of a analyte-specific receptors. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.Type: ApplicationFiled: December 8, 2000Publication date: June 21, 2001Inventors: Dennis S. Everhart, Rosann M. Kaylor, Kevin McGrath
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Patent number: 6221579Abstract: The present invention provides an inexpensive and sensitive system and method for detecting analytes present in a medium. The system comprises a diffraction enhancing element, such as functionalized microspheres, which are modified such that they are capable of binding with a target analyte. Additionally, the system comprises a polymer film, which may include a metal coating, upon which is printed a specific, predetermined pattern of a analyte-specific receptors. Upon attachment of a target analyte to select areas of the polymer film, either directly or with the diffraction enhancing element, diffraction of transmitted and/or reflected light occurs via the physical dimensions and defined, precise placement of the analyte. A diffraction image is produced which can be easily seen with the eye or, optionally, with a sensing device.Type: GrantFiled: December 11, 1998Date of Patent: April 24, 2001Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Dennis S. Everhart, Rosann M. Kaylor, Kevin McGrath
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Patent number: 6180288Abstract: The present invention comprises an optically diffracting sensing device whose diffraction pattern changes upon exposure to some stimuli. The diffraction pattern may be two or three dimensional, and in one embodiment the change in diffraction patterns is recognizable to the untrained eye. The device comprises one or more gels coated onto patterned, self-assembling monolayers of alkanethiolates, carboxylic acids, hydroxamic acids, and phosphonic acids printed onto a variety of substrates, including glass, silicon, aluminum oxide, and thermoplastic films metallized with gold, or with an alloy such as nickel/gold. The present invention also comprises the method of making this device, and the use of this device.Type: GrantFiled: March 21, 1997Date of Patent: January 30, 2001Assignee: Kimberly-Clark Worldwide, Inc.Inventors: Dennis S. Everhart, Rosann M. Kaylor, Mark L. Jones
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Patent number: 5603830Abstract: An adsorbent filter for removing caffeine from liquids. The filter is composed of a matrix of fibrous material; and adsorbent particulate material integrated within the matrix of fibrous material, so that passage of a liquid having a caffeine concentration ranging from about 20 to about 100 mg per 100 mL of liquid through the matrix for a contact time of less than about 2 minutes results in at least a 40 percent reduction in the caffeine concentration of the liquid. The matrix of fibrous material may be selected from woven fabrics, knit fabrics and nonwoven fabrics. The adsorbent material may be clay minerals such as, for example, smectite clay minerals. Examples of smectite clay minerals include, bentonite clays and montmorillonite clays. Generally speaking, the filter can be adapted to provide at least a 40 percent reduction in the caffeine concentration for about 1 cup to about 40 cups of a liquid.Type: GrantFiled: May 24, 1995Date of Patent: February 18, 1997Assignee: Kimberly-Clark CorporationInventors: Dennis S. Everhart, Rosann M. Kaylor, Kenneth R. Smith
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Patent number: 5538629Abstract: Disclosed is a process for disinfecting water which provides a visual indication after the disinfection is complete. First, the water to be disinfected is generally simultaneously intermixed with at least three items. The items are: (1) a disinfectant which is adapted to render harmless substantially all pathogens present in the water upon the disinfectant being intermixed with the water for a time period T.sub.k ; (2) a colorant; and (3) a material which can remove substantially all of the disinfectant and colorant from the water over a time period t.sub.r, where T.sub.r is greater than T.sub.k. Secondly, the water, disinfectant, colorant and the removing material are allowed to remain intermixed for a time period of T.sub.r or greater. At the end of the time period T.sub.r, substantially all pathogens in the water will be rendered harmless, substantially all of the disinfectant will be removed from the water and substantially all of the colorant will be removed from the water.Type: GrantFiled: December 15, 1994Date of Patent: July 23, 1996Assignee: Kimberly-Clark CorporationInventors: Carol A. Blaney, Kristi L. Kiick-Fischer, Rosann M. Kaylor