Patents by Inventor Rosanna Eccel

Rosanna Eccel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tetracyclic indole derivatives for treating hypertension
    Patent number: 4801588
    Abstract: Compounds of the formula I: ##STR1## wherein R.sub.1 =H, CH.sub.3 ; m=0,1; R.sub.2 =R.sub.3 =H or R.sub.2, R.sub.3 =bond, R.sub.4 =C.sub.1 -C.sub.4 hydrocarbon, n=1 or 2 and their pharmaceutically acceptable salts are antihypertensive agents. Their preparation and pharmaceutical compositions containing them are also described.
    Type: Grant
    Filed: July 15, 1987
    Date of Patent: January 31, 1989
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventors: Aldemio Temperilli, Rosanna Eccel, Enzo Brambilla, Patricia Salvati
  • 8-pyridazinylcarbamoyl ergolines
    Patent number: 4675404
    Abstract: Ergoline derivatives of formula: ##STR1## wherein n=0,1,2; R.sub.1 =H, CH.sub.3 ; R.sub.2 =H, CH.sub.3, halogen; R.sub.3 =H, OCH.sub.3 ; R.sub.4 =hydrocarbon group and R.sub.5 is a residue of general formula II, III, IV, V, VI, VII: ##STR2## wherein R.sub.6 =H, Cl, OCH.sub.3, NR.sub.11 R.sub.12, wherein R.sub.11 and R.sub.12 =H, lower alkyl; phenyl or are bonded together to form a heterocyclic ring, R.sub.7, R.sub.8 and R.sub.9 and R.sub.10 =H or C.sub.1 -C.sub.3 alkyl, with the proviso that if R.sub.5 is of formula II and R.sub.2 =R.sub.7 =R.sub.8 =H, then R.sub.4 is not methyl or n is not 0.Pharmaceutically acceptable acid addition salts are also provided. A method for their preparation is also provided.The compounds have anti-depressive, anti-hypertensive and antiprolactin activity.
    Type: Grant
    Filed: July 14, 1986
    Date of Patent: June 23, 1987
    Assignee: Farmitala Carlo Erba S.p.A.
    Inventors: Luigi Bernardi, Aldemio Temperilli, Germano Bosisio, Gabriella Traquandi, Rosanna Eccel, Alessandro Rossi, Patricia Salvati