Patents by Inventor Rose C. Beck

Rose C. Beck has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOTCH INDUCED NATURAL KILLER CELL GENERATION AND THERAPEUTIC USES
    Publication number: 20140186319
    Abstract: A method of preparing differentiated NK cells by ex vivo expansion includes the steps of; (1) isolating a plurality of CD34+ hematopoietic cells; (2) culturing the cells in a medium, wherein the medium includes an effective amount of a notch ligand and one or more cytokines selected from the group consisting of IL-7, IL-15, SCF, Flt-3, IL-3 and IL-6; and (3) maintaining the cells in culture for a duration of time sufficient to produce NK cells.
    Type: Application
    Filed: July 26, 2013
    Publication date: July 3, 2014
    Applicant: Case Western Reserve University
    Inventor: Rose C. Beck
  • Notch induced natural killer cell generation and therapeutic uses
    Patent number: 8518397
    Abstract: A method of preparing differentiated NK cells by ex vivo expansion includes the steps of; (1) isolating a plurality of CD34+ hematopoietic cells; (2) culturing the cells in a medium, wherein the medium includes an effective amount of a notch ligand and one or more cytokines selected from the group consisting of IL-7, IL-15, SCF, Flt-3, IL-3 and IL-6; and (3) maintaining the cells in culture for a duration of time sufficient to produce NK cells.
    Type: Grant
    Filed: August 12, 2010
    Date of Patent: August 27, 2013
    Assignee: Case Western Reserve University
    Inventor: Rose C. Beck
  • NOTCH INDUCED NATURAL KILLER CELL GENERATION AND THERAPEUTIC USES
    Publication number: 20110044962
    Abstract: A method of preparing differentiated NK cells by ex vivo expansion includes the steps of; (1) isolating a plurality of CD34+ hematopoietic cells; (2) culturing the cells in a medium, wherein the medium includes an effective amount of a notch ligand and one or more cytokines selected from the group consisting of IL-7, IL-15, SCF, Flt-3, IL-3 and IL-6; and (3) maintaining the cells in culture for a duration of time sufficient to produce NK cells.
    Type: Application
    Filed: August 12, 2010
    Publication date: February 24, 2011
    Inventor: Rose C. Beck