Patents by Inventor Rose D'Alisa

Rose D'Alisa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the inactivation of viruses in viral-contaminated pharmaceutical compositions
    Patent number: 5300433
    Abstract: The present invention provides a fail-safe combination of chemical and physical means for rendering a blood product which comprises a labile blood protein free of viruses without incurring protein denaturation. The blood product is contacted with an effective amount of a selected chemical disinfectant, preferably, sodium thiocyanate in combination with a physical process, preferably, ultrafiltration. The blood product may be plasma, serum, plasma concentrate, cryoprecipitate, cryosupernatant, plasma fractionation precipitate or plasma fractionation supernatant containing viruses such as hepatitis or human immunodeficiency virus.
    Type: Grant
    Filed: September 25, 1991
    Date of Patent: April 5, 1994
    Assignee: Rhone-Poulenc Rorer Pharmaceuticals Inc.
    Inventors: Michael E. Hrinda, Rose D'Alisa, George C. Tarr