Patents by Inventor Rose-Marie Handjani

Rose-Marie Handjani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20010010824
    Abstract: Composition comprising biodegradable nanoparticles encapsulating oils which are active and/or which contain an active ingredient having a cosmetic and/or pharmaceutical action in the upper layers of the epidermis. The nanoparticles are preferably prepared from a polymer of (C2-C12) alkyl cyanoacrylate.
    Type: Application
    Filed: January 23, 2001
    Publication date: August 2, 2001
    Applicant: L'Oreal
    Inventors: Rose-Marie Handjani, Alain Ribier
  • Patent number: 6203802
    Abstract: Composition comprising biodegradable nanoparticles encapsulating oils which are active and/or which contain an active ingredient having a cosmetic and/or pharmaceutical action in the upper layers of the epidermis. The nanoparticles are preferably prepared from a polymer of (C2-C12) alkyl cyanoacrylate.
    Type: Grant
    Filed: February 14, 1994
    Date of Patent: March 20, 2001
    Assignee: L'Oreal
    Inventors: Rose-Marie Handjani, Alain Ribier
  • Patent number: 5993831
    Abstract: A composition containing, in a suitable carrier, nanoparticles of one or more nonbiodegradable polymer(s) encapsulating an oily phase which contains at least one active oil and/or at least one carrier oil and/or at least one active ingredient in an active oil and/or a carrier oil. At least one active ingredient is chosen from those with prolonged cosmetic and/or pharmaceutical activity. The nanocapsules have a size of 100-1000 nm.
    Type: Grant
    Filed: May 10, 1993
    Date of Patent: November 30, 1999
    Assignee: L'Oreal
    Inventors: Alain Ribier, Pascal Richart, Rose-Marie Handjani
  • Patent number: 5866158
    Abstract: The vesicles are prepared from a lipid phase containing a mixture of nonionic amphiphilic lipids consisting of a mixture of esters of at least one polyol chosen from the group composed of polyethylene glycol containing from 1 to 60 ethylene oxide units, sorbitan, sorbitan bearing 2 to 60 ethylene oxide units, glycerol bearing 2 to 30 ethylene oxide units, polyglycerols containing 2 to 15 glycerol units, sucroses, and glucoses bearing 2 to 30 ethylene oxide units and of at least one fatty acid containing a saturated or unsaturated, linear or branched C.sub.5 -C.sub.17 alkyl chain, the number of alkyl chains per polyol group being between 1 and 10, the mixture being stabilized with ionic amphiphilic lipid or lipids chosen from the group composed of those which impart a pH of between 5.5 and 7.5 to the dispersion.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: February 2, 1999
    Assignee: L'Oreal
    Inventors: Alain Ribier, Jean-Thierry Simonnet, Rose-Marie Handjani, Nadia Terren
  • Patent number: 5741518
    Abstract: The vesicles are prepared from a lipid phase containing a mixture of nonionic amphiphilic lipids consisting of a mixture of esters of at least one polyol chosen from the group composed of polyethylene glycol containing from 1 to 60 ethylene oxide units, sorbitan, sorbitan bearing 2 to 60 ethylene oxide units, glycerol bearing 2 to 30 ethylene oxide units, polyglycerols containing 2 to 15 glycerol units, sucroses, and glucoses bearing 2 to 30 ethylene oxide units and of at least one fatty acid containing a saturated or unsaturated, linear or branched C.sub.5 -C.sub.17 alkyl chain, the number of alkyl chains per polyol group being between 1 and 10, the mixture being stabilized with ionic amphiphilic lipid or lipids chosen from the group composed of those which impart a pH of between 5.5 and 7.5 to the dispersion.
    Type: Grant
    Filed: August 16, 1996
    Date of Patent: April 21, 1998
    Assignee: L'Oreal
    Inventors: Alain Ribier, Jean-Thierry Simonnet, Rose-Marie Handjani, Nadia Terren
  • Patent number: 5556617
    Abstract: A composition containing, in a suitable carrier, nanoparticles of one or more nonbiodegradable polymer(s) encapsulating an oily phase which contains at least one active oil and/or at least one carrier oil and/or at least one active ingredient in an active oil and/or a carrier oil. At least one active ingredient is chosen from those with prolonged cosmetic and/or pharmaceutical activity. The nanocapsules have a size of 100-1000 nm.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 17, 1996
    Assignee: L'Oreal
    Inventors: Alain Ribier, Pascal Richart, Rose-Marie Handjani
  • Patent number: 5489426
    Abstract: A cosmetic composition which is a dispersion of spheres in an external aqueous phase. The spheres are organized molecular layers of a nonionic lipid material encapsulating an internal aqueous phase. The external aqueous phase contains an oil.
    Type: Grant
    Filed: February 14, 1990
    Date of Patent: February 6, 1996
    Assignee: L'Oreal
    Inventors: Arlette Zabotto, Jacqueline Griat, Rose-Marie Handjani, Guy G. Vanlerberghe, Alain J. Ribier
  • Patent number: 5439672
    Abstract: A cosmetic composition which is a stabilized, oil-in-water dispersion of spheres in an external aqueous phase. The spheres are organized molecular layers of a nonionic amphiphilic lipid material encapsulating an internal aqueous phase. The external aqueous phase, containing an oil, is free of any surface active emulsifying agent.
    Type: Grant
    Filed: November 18, 1993
    Date of Patent: August 8, 1995
    Assignee: L'Oreal
    Inventors: Arlette Zabotto, Jacqueline Griat, Rose-Marie Handjani, Guy G. Vanlerberghe, Alian J. Ribier
  • Patent number: 5290565
    Abstract: Composition for promoting healing containing, as a healing agent, nonionic vesicles obtained from a lipid mixture containing at least one nonionic lipid having the formula; ##STR1## wherein R is either at least one C.sub.16 -C.sub.18 radical, or R'CO wherein R' is at least one C.sub.15 -C.sub.17 alkyl radical, in combination with cholesterol and, optionally, dicetylphosphate or tetracetylphospate.This composition can be used topically to accelerate the scarring of wounds.
    Type: Grant
    Filed: May 13, 1992
    Date of Patent: March 1, 1994
    Assignee: L'Oreal
    Inventors: Alexandre Zysman, Henri Sebag, Guy Vanlerberghe, Rose-Marie Handjani, Alain Ribier
  • Patent number: 5204111
    Abstract: A process for producing alginate capsules comprises slowly introducing an aqueous alginate solution into crosslinking solution of a polyvalent metal salt. The aqueous alginate solution has mannuronic units (M) and guluronic units (G) in a molar ratio between 0.4 and 1.9 and preferably an amount of (G) blocks greater than 50%. Preferably, the alginate is a sodium alginate having a viscosity, in a 0.5% solution in water at 25.degree. C., lower than 20 mPa.s measured with a TV Contraves viscosimeter having a No. 1 measurement body in the presence of a calcium chelate. The alginate concentration is between 0.2 and 2 weight percent. The polyvalent metal salt concentration in solution is from 3.4.times.10.sup.-3 to 6.8.times.10.sup.-2 M. The alginate capsules are employed in cosmetic compositions.
    Type: Grant
    Filed: January 28, 1992
    Date of Patent: April 20, 1993
    Assignee: L'Oreal
    Inventors: Rose-Marie Handjani, Myriam Kauffmann, Frederic Huguenin
  • Patent number: 5139783
    Abstract: A process for producing alginate capsules comprises slowly introducing an aqueous alginate solution into crosslinking solution of a polyvalent metal salt. The aqueous alginate solution has mannuronic units (M) and guluronic units (G) in a molar ratio between 0.4 and 1.9 and preferably an amount of (G) blocks greater than 50%. Preferably, the alginate is a sodium alginate having a viscosity, in a 0.5% solution in water at 25.degree. C. lower than 20 mPa.s measured with a TV Contraves viscosimeter having a No. 1 measurement body in the presence of a calcium chelate. The alginate concentration is between 0.2 and 2 weight percent. The polyvalent metal salt concentration in solution is from 3.4.times.10.sup.-3 to 6.8.times.10.sup.-2 M.The alginate capsules are employed in cosmetic compositions.
    Type: Grant
    Filed: April 9, 1990
    Date of Patent: August 18, 1992
    Assignee: L'Oreal
    Inventors: Rose-Marie Handjani, Myriam Kauffmann, Frederic Huguenin
  • Patent number: 5079227
    Abstract: A perfume composition, with an aqueous phase, having a high concentration of perfume, which contains:a) vesicles which are obtained from at least one non-ionic lipid derived from a linear or branched polyglycerol, associated with a stabilizer present in a proportion of 1 to 10% by weight based on the lipid, the vesicles having an average diameter of between 0.01 .mu. and 1 .mu. and the lipids which form the vesicles representing 0.2 to 4% by weight of the total composition; andb) a perfume in the form of droplets having an average diameter of between 0.1 .mu. and 1 .mu. and being present in the composition in amounts of between 3 and 20% by weight based on the total composition, the total ratio of the lipid or lipids of the vesicles to the perfume being between 0.05 and 0.2.
    Type: Grant
    Filed: August 1, 1990
    Date of Patent: January 7, 1992
    Assignee: L'Oreal
    Inventors: Rose-Marie Handjani, Arlette Zabotto, Alain Ribier, Jacqueline Griat
  • Patent number: 5034217
    Abstract: An anhydrous cosmetic makeup composition for the lips and skin contains crosslinked poly .beta.-alanine microspheres impregnated with a polyhydric alcohol.
    Type: Grant
    Filed: April 24, 1989
    Date of Patent: July 23, 1991
    Assignee: Societe Anonyme dite: "L'Oreal"
    Inventors: Beatrice DeFrossez, Rose-Marie Handjani-Vila, Claudine Lapoiriere, Claude Mahieu, Christos Papantoniou, Jean-Claude Ser
  • Patent number: 5021200
    Abstract: A process for producing a dispersion of spherules of a lipid compound encapsulating an aqueous phase includes admixing a water-dispersible lipid compound with an aqueous phase to be encapsulated in the spherules, agitating the resulting mixture to form a lamellar phase, adding a liquid dispersion phase and vigorously shaking the resulting mixture.
    Type: Grant
    Filed: September 14, 1989
    Date of Patent: June 4, 1991
    Assignee: Societe Anonyme dite: L'Oreal
    Inventors: Guy Vanlerberghe, Rose-Marie Handjani
  • Patent number: 4897308
    Abstract: A mixture of at least two aqueous dispersions of non-ionic lipid spherules encapsulating an aqueous phase containing an active substance. The active substance encapsulated in the spherules of one of the dispersions is different from the active substance encapsulated in the spherules of another of the dispersions.
    Type: Grant
    Filed: June 8, 1988
    Date of Patent: January 30, 1990
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Rose-Marie Handjani nee Villa
  • Patent number: 4772471
    Abstract: A dispersion in a continuous phase or spherules comprises arranged molecular layers of a non-ionic lipid compound encapsulating an aqueous phase wherein the non-ionic lipid compound has a lipophile group/hydrophile group ratio such that the non-ionic lipid compound swells in the aqueous phase to be encapsulated therein so as to form a lamellar phase. The hydrophile group of the non-ionic compound is selected from the group consisting of polyoxyethylene groups, polyglycerol groups and esters of polyols. The spherules have a diameter between 1,000 .ANG. and 50,000 .ANG..
    Type: Grant
    Filed: December 12, 1979
    Date of Patent: September 20, 1988
    Assignee: Societe Anonyme dite: L'Oreal
    Inventors: Guy Vanlerberghe, Rose-Marie Handjani
  • Patent number: 4608211
    Abstract: A process for preparing large unilamellar lipid vesicles is disclosed which process comprises preparing unilamellar lipid vesicles having an average diameter of at least 1,000 .ANG., each of these vesicles consisting of a spheroidal lipid lamella containing a substance to be encapsulated, which process comprises dissolving one or more lipids intended to form the lamella of the vesicles in at least one water-insoluble solvent, conditioning the resulting lipid solution at a pressure P.sub.1 and at a temperature .theta..sub.1, dissolving the substance to be encapsulated in water to obtain an aqueous phase, conditioning said aqueous phase at a pressure P.sub.2 and a temperature .theta..sub.2, injecting the lipid solution into the aqueous phase at a low flow rate so as initially to form droplets and so that solvent of the lipid solution vaporises on coming into contact with the said aqueous phase, the pressure P.sub.2 being less than P.sub.
    Type: Grant
    Filed: March 8, 1984
    Date of Patent: August 26, 1986
    Assignee: L'Oreal
    Inventors: Rose-Marie Handjani, Alain Ribier, Manlio M. Maurelli
  • Patent number: 4217344
    Abstract: The present invention relates to a process for producing a dispersion of spheres comprising arranged molecular layers encapsulating an aqueous phase. The process comprises admixing a water-dispersible lipid component with the aqueous phase to be encapsulated, the liphophile/hydrophile ratio of the lipid component being such that the lipid swells in the said aqueous phase so as to form a lamellar phase. The lamellar phase is agitated and there is added thereto a dispersion liquid in an amount greater than the resulting lamellar phase and the resulting mixture is vigorously agitated for a period of time ranging from 15 minutes to 3-4 hours. The spheres can encapsulate a water-soluble pharmaceutical, a cosmetic or a food and the dispersions containing said encapsulated materials can be used particularly in the pharmaceutical and cosmetic fields.
    Type: Grant
    Filed: December 29, 1977
    Date of Patent: August 12, 1980
    Assignee: L'Oreal
    Inventors: Guy Vanlerberghe, Rose-Marie Handjani
  • Patent number: 4032628
    Abstract: An emulsion comprises an oil phase and a water phase emulsified with an emulsifying agent consisting essentially of at least one block polymer containing both at least one lipophilic sequence and at least one hydrophilic sequence.
    Type: Grant
    Filed: November 5, 1975
    Date of Patent: June 28, 1977
    Assignee: Societe Anonyme dite: L'Oreal
    Inventors: Christos Papantoniou, Rose-Marie Handjani