Patents by Inventor Rose Whelan

Rose Whelan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • A METHOD FOR CLASSIFYING THE GUT INFLAMMATION STATUS IN AVIAN SPECIES
    Publication number: 20240002943
    Abstract: The invention provides a method for classifying the gut inflammation status of an avian subject or of a group of avian subjects to be tested, the method comprising the comparison of the average methylation levels within a panel of pre-selected LMRs in the genomic DNA isolated from gut sample material deriving from the individual avian subject or of the group of avian subjects to be tested with the average methylation levels of the same panel of LMRs in the genomic DNA pertaining to one or more reference samples having a negative gut inflammation status.
    Type: Application
    Filed: November 22, 2021
    Publication date: January 4, 2024
    Applicant: Evonik Operations GmbH
    Inventors: Florian BÖHL, Frank LYKO, Walter PFEFFERLE, Andreas KAPPEL, Rose WHELAN, Günter RADDATZ, Monika FLÜGEL, Stefan PELZER, Achim MARX, Emery STEPHANS, Frank THIEMANN, Emeka Ignatius IGWE
  • A CHICKEN METHYLATION CLOCK
    Publication number: 20230051524
    Abstract: The invention provides a method of establishing a chicken methylation clock comprising: (a) determining the methylation ratio and the read coverage of the genomic CpG sites of an age-correlated training sample of a specific chicken tissue; (b) defining a set of CpG sites having reliable methylation ratios in all training samples of step (a) using a cutoff value; and (c) performing a penalized regression using the methylation ratios of step (b) as input and the age correlated to the training sample as dependent variable, by applying a penalized regression model; thereby obtaining a set of CpG sites with corresponding weighting factors and intercept of the linear model equation as parameters defining the chicken methylation clock.
    Type: Application
    Filed: December 8, 2020
    Publication date: February 16, 2023
    Applicant: Evonik Operations GmbH
    Inventors: Florian BOEHL, Frank LYKO, Rose WHELAN, Andreas KAPPEL, Emeka Ignatius IGWE, Frank THIEMANN, Guenter RADDATZ
  • strain with probiotic activity
    Patent number: 11173184
    Abstract: The current invention concerns a new B. subtilis strain with strong inhibition of C. perfringens and its use as a probiotic.
    Type: Grant
    Filed: May 29, 2017
    Date of Patent: November 16, 2021
    Assignee: Evonik Operations GmbH
    Inventors: Daniel Petri, Stefan Pelzer, Jessica Kleinbölting, Stella Molck, Maike Kipker, Claudia Borgmeier, Sandra Herbold, Guido Meurer, Rose Whelan, Kiran Doranalli
  • BACILLUS LICHENIFORMIS STRAIN WITH PROBIOTIC ACTIVITY
    Publication number: 20210228653
    Abstract: The current invention concerns a new B. licheniformis strain with strong inhibition of C. perfringens and its use as probiotic.
    Type: Application
    Filed: May 24, 2017
    Publication date: July 29, 2021
    Applicant: EVONIK DEGUSSA GMBH
    Inventors: Daniel Petri, Stefan PELZER, Jessica KLEINBÖLTING, Stella MOLCK, Maike KIPKER, Claudia BORGMEIER, Sandra HERBOLD, Guido MEURER, Rose WHELAN, Kiran DORANALLI
  • BACILLUS SUBTILIS STRAIN WITH PROBIOTIC ACTIVITY
    Publication number: 20170340683
    Abstract: The current invention concerns a new B. subtilis strain with strong inhibition of C. perfringens and its use as a probiotic.
    Type: Application
    Filed: May 29, 2017
    Publication date: November 30, 2017
    Inventors: Daniel Petri, Stefan Pelzer, Jessica Schneider, Stella Molck, Maike Kipker, Claudia Borgmeier, Sandra Herbold, Guido Meurer, Rose Whelan, Kiran Doranalli
  • PROBIOTIC BACTERIA AS CARRIER FOR A HELMINTH-DERIVED IMMUNOMODULATOR FOR THE TREATMENT OF INFLAMMATORY DISORDERS
    Publication number: 20150216932
    Abstract: The present invention is directed to a transgenic probiotic microorganism genetically engineered to express and secrete cystatin, wherein said cystatin is preferably comprises or consists of: an amino acid sequence with SEQ ID NO. 1 to 3; and an amino acid sequence that is at least 70% identical, preferably at least 80% identical, more preferably at least 90% identical and most preferably at least 99% identical to an amino acid sequence with SEQ ID NO. 1 to 3, and to its use for treatment of gastrointestinal inflammatory diseases.
    Type: Application
    Filed: September 6, 2013
    Publication date: August 6, 2015
    Inventors: Susanne Hartmann, Lothar Wieler, Rose Whelan, Sebastian Rausch