Patents by Inventor Rosemarie Grabs

Rosemarie Grabs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DNA assay for the prediction of autoimmune diabetes
    Patent number: 6534272
    Abstract: The present invention relates to a novel DNA assay for the diagnosis and/or prediction of autoimmune diabetes. The present invention relates to a DNA assay for the prediction of autoimmune diabetes in human subjects, which comprises the steps of a) obtaining a DNA sample from the subject and amplifying at least one class III allele of variable number of tandem repeats (VNTR) located upstream of the insulin gene (INS) which is associated with silencing of thymic insulin mRNA expression; and b) subjecting the sample to electrophoresis to identify the silencing class III allele.
    Type: Grant
    Filed: July 23, 2001
    Date of Patent: March 18, 2003
    Assignee: McGill University
    Inventors: Constantin Polychronakos, Petros Vafiadis, Rosemarie Grabs, Houria Ounissi-Benkalha
  • DNA assay for the prediction of autoimmune diabetes
    Publication number: 20020160376
    Abstract: The present invention relates to a novel DNA assay for the diagnosis and/or prediction of autoimmune diabetes. The present invention relates to a DNA assay for the prediction of autoimmune diabetes in human subjects, which comprises the steps of a) obtaining a DNA sample from the subject and amplifying at least one class III allele of variable number of tandem repeats (VNTR) located upstream of the insulin gene (INS) which is associated with silencing of thymic insulin mRNA expression; and b) subjecting the sample to electrophoresis to identify the silencing class III allele.
    Type: Application
    Filed: July 23, 2001
    Publication date: October 31, 2002
    Inventors: Constantin Polychronakos, Petros Vafiadis, Rosemarie Grabs, Houria Ounissi-Benkalha