Patents by Inventor Rosemary B. Duda

Rosemary B. Duda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant mycobacterial vaccines
    Patent number: 5776465
    Abstract: The present invention relates to recombinant mycobacteria, particularly recombinant M. bovis BCG, which express heterologous DNA encoding a product (protein or polypeptide) of interest, such a protein or polypeptide (e.g., an antigen) against which an immune response is desired, or a cytokine.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: July 7, 1998
    Assignees: Beth Israel Hospital Association, Whitehead Institute for Biomedical Research
    Inventors: Michael A. O'Donnell, Rosemary B. Duda, William C. DeWolf, Anna Aldovini, Richard A. Young
  • Recombinant BCG
    Patent number: 5591632
    Abstract: The present invention relates to recombinant mycobacteria, particularly recombinant M. bovis BCG, which express heterologous DNA encoding a product (protein or polypeptide) of interest, such a protein or polypeptide (e.g., an antigen) against which an immune response is desired or a cytokine.
    Type: Grant
    Filed: July 22, 1993
    Date of Patent: January 7, 1997
    Assignees: Beth Israel Hospital, Whitehead Institute For Biomedical Research
    Inventors: Michael A. O'Donnell, Rosemary B. Duda, William C. DeWolf, Anna Aldovini, Richard A. Young
  • Method of enhancing the biodistribution of antibody for localization in lesions
    Patent number: 4921690
    Abstract: A method for enhancing the biodistribution of antibody for localization in lesions comprising initially exposing a mammalian subject containing lesion-associated marker substance to a first antibody specific for a given epitope of the marker substance, and after a period of time such that the marker substance has associated with the antibody, exposing the mammal to a further amount of the same antibody, or a second antibody specific either for an epitope of the marker substance different from the epitope for which the first antibody is specific, or for the same epitope of the marker substance as the first antibody but of a different binding affinity from the first antibody.
    Type: Grant
    Filed: April 12, 1988
    Date of Patent: May 1, 1990
    Assignee: City of Hope
    Inventors: John D. Beatty, Barbara G. Beatty, Rosemary B. Duda