Patents by Inventor Roshni Davey

Roshni Davey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GENETIC MODIFICATION OF THE HYDROXYACID OXIDASE 1 GENE FOR TREATMENT OF PRIMARY HYPEROXALURIA
    Publication number: 20220090047
    Abstract: Disclosed are engineered nucleases that bind and cleave a recognition sequence within a hydroxyacid oxidase 1 (HAO1) gene. The present invention also encompasses methods of using such engineered nucleases to make genetically-modified cells. Further, the invention encompasses pharmaceutical compositions comprising engineered nuclease proteins or nucleic acids encoding engineered nucleases of the invention, and the use of such compositions for treatment of primary hyperoxaluria type I.
    Type: Application
    Filed: December 20, 2019
    Publication date: March 24, 2022
    Applicant: Precision BioSciences, Inc.
    Inventors: Roshni Davey, Derek Jantz, James Jefferson Smith, Gary Owens