Abstract: The present invention relates to platinum (IV) prodrug lipid-based amphiphiles and compositions thereof. In particular, it relates to cisplatin, oxaliplatin and carboplatin prodrugs with the capacity to make stable liquid crystalline nanoparticles and crystalline nanoparticles, and uses thereof to treat cancer in animals, including humans.

Abstract: The present invention relates to improved prodrugs, and compositions thereof. In particular, it relates to amphiphilic gemcitabine prodrugs or amphiphilic prodrugs of other biologically active molecules with the capacity to make liquid crystalline nanostructured nanoparticles, and uses thereof to treat animals, including humans.

Abstract: A system for introducing a fine bore catheter into a vein includes a cannula unit comprising an elongate tubular sheath, defining a distal end and a proximal end, and a hub enclosing the proximal end of the sheath. The cannula unit is adapted to receive an introducing needle for introducing the distal end of the sheath of the cannula into a vein. The system also includes a catheter unit, having a distal end and a proximal end, a body portion located at the proximal end of the catheter unit, and a catheter tube extending from the body portion to the distal end of the catheter unit.