Abstract: The E3 ubiquitin ligases which are specific to ubiquitination of proteins relevant to bone formation are useful targets for protocols or compounds to ameliorate bond disorders. These ligases are &bgr;-TrCP, Smurf1 and Smurf2.

Abstract: An automated system and method for broadcasting meetings over a computer network. The meeting is filmed using an omni-directional camera system and capable of being presented to a viewer both live and on-demand. The system of the present invention includes an automated camera management system for controlling the camera system and an analysis module determining the location of meeting participants in the meeting environments. The method of the present invention includes using the system of the present invention to broadcast an event to a viewer over a computer network. In particular, the method includes filming the event using an omni-directional camera system. Next, the method determines the location of each event participant in the event environment. Finally, a viewer is provided with a user interface for viewing the broadcast event. This user interface allows a viewer to choose which event participant that the viewer would like to view.

Abstract: Compounds that inhibit the activity of NF-&kgr;B or inhibit the activity of the proteasome or both promote bone formation and are thus useful in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgery, and post-dental implantation.

Abstract: Compounds that inhibit the activity of NF-&kgr;B or inhibit the activity of the proteasome or both promote bone formation and hair growth and are thus useful in treating osteoporosis, bone fracture or deficiency, primary or secondary hyperparathyroidism, periodontal disease or defect, metastatic bone disease, osteolytic bone disease, post-plastic surgery, post-prosthetic joint surgery, and post-dental implantation; they also stimulate the production of hair follicles and are thus useful in stimulating hair growth, including hair density, in subject where this is desirable.

Abstract: Compounds that inhibit the activity of NF-&kgr;B or inhibit the activity of the proteasome or both promote hair growth and stimulate the production of hair follicles and are thus useful in stimulating hair growth, including hair density, in subject where this is desirable.

Abstract: Compounds that inhibit the activity of NF-&kgr;B or inhibit the activity of the proteasome or both promote hair growth and stimulate the production of hair follicles and are thus useful in stimulating hair growth, including hair density, in subject where this is desirable.

Abstract: A food or food supplement which comprises a compound that enhances bone growth in vertebrates is described wherein the food or foodstuff is formulated so as to provide the desired bone growth enhancing effect.